Harmonizing Terrestrial Carbon Cycle Observations Over CONUS NEON Sites: Assessing the Information Contributions of Multiple Data Constraints. [PDF]
Zhang D +4 more
europepmc +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Absolute thermometry based on Brillouin scattering in gases. [PDF]
Yang Y, Soto MA, Thévenaz L.
europepmc +1 more source
Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan +10 more
wiley +1 more source
Do you see what I see? Linking involuntary nonretinal (phantom) vision and mental imagery in aphantasia. [PDF]
Keogh R, Kay L, Meagher C, Pearson J.
europepmc +1 more source
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu +4 more
wiley +1 more source
Technical validation of a virtual reality-based eye tracker for neuro-ophthalmic assessment: a reliability and reproducibility study. [PDF]
Karaer I +10 more
europepmc +1 more source
Development of immunocompetent models for primary and metastatic ER+ breast cancer
This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull +5 more
wiley +1 more source
High gas-pressure apparatus for nonlinear X-ray propagation and reshaping via stimulated X-ray Raman scattering. [PDF]
Magunia A +14 more
europepmc +1 more source

