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Pathological Variables and Laboratory Values in Infants with Neonatal Cholestasis Showing Nonexcretion on Tc-99m Mebrofenin Hepatobiliary Scans: A Descriptive Study. [PDF]
Nair A, Ponnusamy M.
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Pediatric Clinics of North America, 2017
Neonatal jaundice is common and usually not concerning when it is secondary to unconjugated hyperbilirubinemia, below the neurotoxic level, and resolves early. Primary care providers should be vigilant, however, about evaluating infants in whom jaundice presents early, is prolonged beyond 2 weeks of life, or presents at high levels.
Karen F. Murray
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Neonatal jaundice is common and usually not concerning when it is secondary to unconjugated hyperbilirubinemia, below the neurotoxic level, and resolves early. Primary care providers should be vigilant, however, about evaluating infants in whom jaundice presents early, is prolonged beyond 2 weeks of life, or presents at high levels.
Karen F. Murray
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Seminars in Perinatology, 2004
Any infant who is jaundiced beyond two to three weeks of life should be evaluated for neonatal cholestasis. Neonatal cholestasis is defined as accumulation of bile substances in blood due to impaired excretion. These infants should always have fractionated serum bilirubin levels checked to differentiate the conjugated hyperbilirubinemia of cholestasis ...
Sridevi, Venigalla, Glenn R, Gourley
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Any infant who is jaundiced beyond two to three weeks of life should be evaluated for neonatal cholestasis. Neonatal cholestasis is defined as accumulation of bile substances in blood due to impaired excretion. These infants should always have fractionated serum bilirubin levels checked to differentiate the conjugated hyperbilirubinemia of cholestasis ...
Sridevi, Venigalla, Glenn R, Gourley
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Neonatal Hyperbilirubinemia and Cholestasis
NeoReviews, 2021A male infant is born via vaginal delivery at 29 weeks’ estimated gestation with a birthweight of 1,490 g to a 22-year-old gravida 1, para 1 woman who presented with preterm labor. No maternal risk factors are identified; all maternal prenatal laboratory findings are negative.
Stijn, Mintjens +2 more
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Neonatal Cholestasis: A Pandora’s Box [PDF]
Neonatal cholestasis (NC) is a diagnostic dilemma frequently countered in a neonatal care unit. Early diagnosis is vital for achieving an optimal patient outcome as many causes of cholestasis such as biliary atresia are time-sensitive and amenable to treatment if analyzed and treated early. Nonetheless, it is not generally simple to analyze these cases
Aakash Pandita, Girish Gupta
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Aetiological factors in neonatal cholestasis
Acta Paediatrica, International Journal of Paediatrics, 2001The aim of the study was to investigate factors of possible importance for the aetiology of neonatal cholestasis. The medical records of 85 cholestatic infants were retrospectively reviewed. The most common diagnoses were extrahepatic biliary atresia (n= 30 patients), α1‐antitrypsin deficiency (n= 11) and progressive familial intrahepatic cholestasis ...
B Fischler
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Cholestasis in neonatal intensive care unit: incidence, aetiology and management
Aim: Prevalence, aetiology, management and outcome of cholestasis were evaluated in infants admitted to neonatal intensive care unit (NICU). Methods: Medical records of all infants admitted to two Italian level III NICUs from January 2005 to August 2007
Emanuele Nicastro +2 more
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The Journal of Pediatrics, 1985
The spectrum of diseases causing neonatal cholestasis presents intriguing problems for future investigation. There are many causes, and the eventual outcome of the specific entity has unique individual features, despite the wide areas of overlap. For example, extrahepatic biliary atresia may be the result of the sporadic occurrence of a virus-induced ...
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The spectrum of diseases causing neonatal cholestasis presents intriguing problems for future investigation. There are many causes, and the eventual outcome of the specific entity has unique individual features, despite the wide areas of overlap. For example, extrahepatic biliary atresia may be the result of the sporadic occurrence of a virus-induced ...
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Imaging of neonatal cholestasis
Seminars in Ultrasound, CT and MRI, 1994In the neonate with cholestasis, clinical features and standard tests of liver function frequently cannot distinguish between diseases of the hepatocyte and those of the biliary tree. Therefore, a multidisciplinary approach to diagnosis is required. A priority in investigation is the identification of patients requiring surgery.
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