Results 11 to 20 of about 316,235 (202)
Neonatal cholestasis must always be considered in a newborn who is jaundiced for more than 14-21 days and a measurement of the serum total and conjugated bilirubin in these infants is mandatory. Conjugated hyperbilirubinaemia, dark urine and pale stools are pathognomic of the neonatal hepatitis syndrome which should be investigated urgently.
McKiernan, Patrick
openaire +3 more sources
Neonatal Cholestasis: A Red Alert for the Jaundiced Newborn
Neonatal jaundice may indicate cholestasis rather than a benign, physiological condition. Any four-week-old newborn with persistent jaundice should have a fractionated bilirubin screen to determine whether the hyperbilirubinemia is unconjugated ...
Dinesh Pashankar, Richard A Schreiber
doaj +2 more sources
Severe Neonatal Cholestasis as an Early Presentation of McCune- Albright Syndrome [PDF]
McCune-Albright syndrome (MAS) is a rare genetic disorder characterized by café-au-lait macules, polyostotic fibrous dysplasia and multiple endocrinopathies. Liver involvement, although described, is a rare complication.
Nicole Coles +8 more
doaj +2 more sources
Isolated cortisol deficiency: A rare cause of neonatal cholestasis
For decades, congenital panhypopituitarism has been recognized to cause infantile cholestasis. However, the identity of the hormone whose deficiency causes such derangement of the liver is not clear. Here, we report four cases of isolated severe cortisol
Abdulrahman Al-Hussaini +4 more
doaj +2 more sources
Severe cholestasis in neonatal extracorporeal membrane oxygenation
Introduction: Cholestasis is a common complication of Extracorporeal Membrane Oxygenation (ECMO) secondary to patient physiology and circuit-induced factors.
Jancaric Michelle +6 more
doaj +2 more sources
Histopathological diagnosis of intra- and extrahepatic neonatal cholestasis [PDF]
The histopathology of the liver is fundamental for the differential diagnosis between intra- and extrahepatic causes of neonatal cholestasis. However, histopathological findings may overlap and there is disagreement among authors concerning those which ...
J.L. Santos +3 more
doaj +4 more sources
Serum alpha-fetoprotein levels in neonatal cholestasis [PDF]
Alpha-fetoprotein (AFP) is used as a tumor marker for hepatocellular carcinoma, hepatoblastoma and germ cell tumors. It may also be elevated in infants with some hepatobiliary disorders.
Hülya Demir +7 more
doaj +2 more sources
Neonatal cholestasis – differential diagnoses, current diagnostic procedures and treatment [PDF]
Cholestatic jaundice in early infancy is a complex diagnostic problem. Misdiagnosis of cholestasis as physiologic jaundice delays the identification of severe liver diseases.
Thomas eGötze +4 more
doaj +2 more sources
OBJECTIVE: To warn pediatricians about the early recognition of cholestasis in newborns and infants. METHODS: A bibliographic research about cholestasis was performed using Medline, and emphasizing the most relevant publications of the last 30 years. RESULTS: The concept of cholestasis and the causes of cholestatic tendency in newborns and infants are ...
F M, Karrer, D D, Bensard
+6 more sources
A Patient with neonatal cholestasis. [PDF]
The patient, a boy born in 1991, showed pronounced polyostotic fibrous dysplasia due to McCune-Albright syndrome, as well as Gilbert syndrome and Charcot-Marie-Tooth neuropathy caused by a DNM2 mutation. In addition, the patient, his sister, mother and maternal grandfather had intermittently increased plasma arginine and lysine levels, most probably ...
Claeys KG +8 more
europepmc +3 more sources

