Results 31 to 40 of about 316,235 (202)

Neonatal giant cell hepatitis secondary to extrahepatic biliary atresia associated with choledochal cyst

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2022
Neonatal hepatitis (NH) and biliary atresia (BA) are the most common causes of cholestasis in infancy. NH is a nonobstructive type of neonatal cholestatic syndrome manifesting with hepatitis. BA is an obstructive inflammatory syndrome of the extrahepatic
Abena Hidangmayum   +4 more
doaj   +1 more source

Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis [PDF]

open access: yes, 2006
Background/Aims: The expression of transporters involved in bile acid homeostasis is differentially regulated during obstructive cholestasis. Since the drug efflux transporter breast cancer resistance protein (BCRP) is known to transport bile acids, we ...
Beuers, Ulrich   +7 more
core   +1 more source

Low incidence of alpha-1-antitrypsin deficiency in Iranian patients with neonatal cholestasis

open access: yesThe Turkish Journal of Gastroenterology, 2015
Background/Aims: There is little data concerning the incidence of alpha-1-antitrypsin”(AAT) deficiency, the most common genetic cause of liver disease, among children with neonatal cholestasis in Iran.
Farzaneh Motamed   +13 more
doaj   +1 more source

Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids. [PDF]

open access: yesPediatr Res, 2023
BACKGROUND: Cyp2c70-/- mice with a human-like bile acid (BA) composition display features of neonatal cholestasis. We assessed whether perinatal ursodeoxycholic acid (UDCA) exposure prevents neonatal cholestasis in Cyp2c70-/- mice and reduces ...
de Vries HD   +9 more
europepmc   +3 more sources

Prevalence and Pregnancy Outcomes of Intrahepatic Cholestasis of Pregnancy

open access: yesJournal of Nepal Health Research Council, 2021
Background: Intrahepatic cholestasis of pregnancy is a common pregnancy-specific liver disease associated with increased risk of adverse fetal and maternal outcomes. We sought to determine its prevalence, risk factors and feto-maternal outcomes. Methods:
Deekshanta Sitaula   +4 more
doaj   +1 more source

Diversity of disorders causing neonatal cholestasis – the experience of a tertiary paediatric centre in Germany

open access: yesFrontiers in Pediatrics, 2014
Background and Objective: Rapidly establishing the cause of neonatal cholestasis is an urgent matter. The aim of this study was to report on the prevalence and mortality of the diverse disorders causing neonatal cholestasis in an academic center in ...
André eHoerning   +8 more
doaj   +1 more source

Case Report: Dramatic Cholestasis Responsive to Steroids in a Newborn Homozygous for H63D HFE Variant

open access: yesFrontiers in Pediatrics, 2022
In a newborn with very precocious liver failure, cholestatic jaundice, and low γ-glutamyl transpeptidase, progressive hepatosplenomegaly induced a progressively worsening respiratory distress, that was successfully treated with steroids.
Luca Filippi   +7 more
doaj   +1 more source

Neonatal cholestasis, when to check your cortisol?

open access: yes, 2012
Introduction. Hypocortisolism is a treatable cause of neonatal cholestasis, but untreated it is potentially dangerous in procedures like a liver biopsy.
Claessen, Femke   +5 more
core   +2 more sources

Cholestasis Reveals Severe Cortisol Deficiency in Neonatal Pituitary Stalk Interruption Syndrome. [PDF]

open access: yesPLoS ONE, 2016
Cholestasis has been reported during the course of congenital hypothalamic-pituitary deficiency, but crucial information is lacking regarding both its origin and prognosis. We aimed to characterize the course of cholestasis and factors contributing to it
Francois-Xavier Mauvais   +4 more
doaj   +1 more source

Aetiology and outcome of neonatal cholestasis in Malaysia [PDF]

open access: yes, 2010
Introduction: Little is known about the epidemiology, causes and outcomes of neonatal cholestasis in the Asian population beyond Japan and Taiwan.
Lee, Way Seah   +3 more
core   +3 more sources

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