Results 51 to 60 of about 34,890 (296)

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Analysis of the disease burden of neonatal encephalopathy due to birth asphyxia and trauma in China from 1990 to 2019 [PDF]

Yixue xinzhi zazhi
Objective To analyze the disease burden and its trend of neonatal encephalopathy due to birth asphyxia and trauma in China from 1990 to 2019.Methods From the Global Burden of Disease Study 2019, data about disability-adjusted life years (DALYs), DALY ...
HUANG Zirui, CHENG Yan, CHEN Guo, YANG Min   +3 more
doaj   +1 more source

Quantitative EEG in the neonatal intensive care unit: Current application and future promise

Annals of the Child Neurology Society, 2023
Importance Quantitative electroencephalography (qEEG) has been used in the neonatal intensive care unit (NICU) for several decades. Recent innovations have led to renewed interest in expanding its role in the NICU with the goal of improving both acute ...
Jennifer C. Keene, Giulia M. Benedetti, Stuart R. Tomko, Réjean M. Guerriero   +3 more
doaj   +1 more source

Genome-wide expression in neonatal encephalopathy [PDF]

, 2019
Developing new treatments for babies with birth asphyxia related brain injury (neonatal encephalopathy) and preventing cerebral palsy is hampered by two major roadblocks.
Montaldo, Paolo
core   +1 more source

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source

Placental pathology and neonatal encephalopathy

International Journal of Gynecology & Obstetrics, 2022
AbstractNeonatal encephalopathy (NE) is an important cause of neonatal morbidity and mortality worldwide; however, there remain gaps in our knowledge about its pathogenesis. The placenta has been implicated in the pathogenesis of this disease but conclusive evidence related to the placental factors that influence it is sparse.
Aine Fox, Emma Doyle, Michael Geary, Breda Hayes   +3 more
openaire   +2 more sources

Ante- and intrapartum risk factors for neonatal hypoxic ischemic encephalopathy

, 2017
To identify obstetrical risk factors for the diagnosis of neonatal hypoxic ischemic encephalopathy (HIE). A secondary aim was to determine the incidence of HIE.
Lars Brudin, Marie Blomberg, Anna-Stina Wanby, Cedergren, Marie,, Lundgren, Cecilia,, Brudin, Lars,, Wanby, Anna-Stina,, Cecilia Lundgren   +7 more
core   +1 more source

Bilirubin Metabolism and Bilirubin Encephalopathy [PDF]

, 2013
During the last 30 years, there has been much advances in the understanding of pathogenisis of neonatal hyperbilirubinemia, but the risk of bilirubin encephalopathy are still remained for the high risk neonates. The mechanisms of bilirubin encephalopathy
이순민, 이철, 남궁란
core   +1 more source

Diagnostic Odyssey of Atypical Long‐Chain 3‐Hydroxyacyl‐CoA Dehydrogenase Deficiency (LCHADD) Explained by Three Allelic Products From Two Pathogenic Variants

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency (LCHADD) is an autosomal recessive mitochondrial defect of long‐chain fatty acid β‐oxidation, caused by biallelic pathogenic variants in HADHA or HADHB. We report a 22‐year‐old male with an atypically mild presentation of LCHADD who was referred to the Undiagnosed Diseases Network (UDN ...
Yutaka Furuta, Lynette C. Rives, T. Andrew Burrow, Thomas A. Cassini, Rory J. Tinker, Amy K. Robertson, Kimberly M. Ezell, Rizwan Hamid, Joy D. Cogan, John A. Phillips III   +9 more
wiley   +1 more source

Perinatal brain damage: The term infant

Neurobiology of Disease, 2016
Perinatal brain injury at term is common and often manifests with neonatal encephalopathy including seizures. The most common aetiologies are hypoxic–ischaemic encephalopathy, intracranial haemorrhage and neonatal stroke. Besides clinical and biochemical
Henrik Hagberg, A. David Edwards, Floris Groenendaal   +2 more
doaj   +1 more source