Results 61 to 70 of about 34,890 (296)

Sex differences in neonatal brain injury and inflammation

Frontiers in Immunology, 2023
Neonatal brain injury and associated inflammation is more common in males. There is a well-recognised difference in incidence and outcome of neonatal encephalopathy according to sex with a pronounced male disadvantage.
Lynne A. Kelly, Lynne A. Kelly, Lynne A. Kelly, Aoife Branagan, Aoife Branagan, Aoife Branagan, Aoife Branagan, Gergana Semova, Gergana Semova, Gergana Semova, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy   +15 more
doaj   +1 more source

Response of an Infant With Presumed Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta, Kaitlyn N. Bloom, Jerry Vockley, Angela R. Grochowsky, Neena S. Agrawal, Ellen W. Strickler, Natalie N. Owen, Erica T. Gray, B. Lakshitha A. Perera, Eric R. Gamazon, Lynette C. Rives, Hua‐Chang Chen, Qi Liu, Rizwan Hamid, Joy D. Cogan, John A. Phillips III, Thomas A. Cassini, Bryce A. Schuler   +17 more
wiley   +1 more source

The role of lymphocytes in neonatal encephalopathy

Brain, Behavior, & Immunity - Health, 2021
Neonatal encephalopathy is a syndrome characterised by abnormal neurological function often caused by a hypoxic insult during childbirth. Triggers such as hypoxia-ischaemia result in the release of cytokines and chemokines inducing the infiltration of neutrophils, natural killer cells, B cells, T cells and innate T cells into the brain.
Ashanty M. Melo, Nawal AB. Taher, Derek G. Doherty, Eleanor J. Molloy   +3 more
openaire   +5 more sources

Cerebral function monitoring in term or near term neonates at MDH : preliminary experience and proposal of a guideline [PDF]

, 2012
Introduction: Cerebral function monitoring (CFM) is a simplified EEG device that is used to monitor cerebral function at the cot-side. Various studies have shown its value in detecting neonatal encephalopathy and electrographic seizures, prognostication ...
Attard, Stephen, Soler, Doriette, Soler, Paul   +2 more
core  

Therapeutic hypothermia in mild neonatal encephalopathy: a national survey of practice in the UK [PDF]

, 2017
Although major cooling trials (and subsequent guidelines) excluded babies with mild encephalopathy, anecdotal evidence suggests that cooling is often offered to these infants.
Dev Prya Singhvi, Oliveira, V, Seetha Shankaran, Vânia Oliveira, Singhvi, DP, Sudhin Thayyil, Paolo Montaldo, Manerkar, S, Shankaran, S, Thayyil, S, Montaldo, P, Josephine Mendoza, Mendoza, J, Peter J Lally, Swati Manerkar, Lally, PJ   +15 more
core   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Ultrasonographic Evaluation of the Neonatal Brain in Cases of Birth Asphyxia [PDF]

International Journal of Anatomy Radiology and Surgery, 2016
Introduction: Hypoxic ischemic encephalopathy (HIE) is a common condition in newborns as a result of birth asphyxia. Affected neonates display a number of clinical features by which the condition may be suspected.
Susmita Giri, Tapan Kumar Jana, Arunabha Tapadar   +2 more
doaj   +1 more source

Disrupted brain connectivity in children treated with therapeutic hypothermia for neonatal encephalopathy

NeuroImage: Clinical, 2021
Therapeutic hypothermia following neonatal encephalopathy due to birth asphyxia reduces death and cerebral palsy. However, school-age children without cerebral palsy treated with therapeutic hypothermia for neonatal encephalopathy still have reduced ...
Arthur P.C. Spencer, Jonathan C.W. Brooks, Naoki Masuda, Hollie Byrne, Richard Lee-Kelland, Sally Jary, Marianne Thoresen, James Tonks, Marc Goodfellow, Frances M. Cowan, Ela Chakkarapani   +10 more
doaj   +1 more source

Communication Challenges in Neonatal Encephalopathy [PDF]

Pediatrics, 2016
BACKGROUND: Families must process complex information related to neonatal encephalopathy and therapeutic hypothermia. METHODS: In this mixed methods study, semi-structured interviews were performed with parents whose infants were enrolled in an ...
Monica E, Lemmon, Pamela K, Donohue, Charlamaine, Parkinson, Frances J, Northington, Renee D, Boss   +4 more
openaire   +2 more sources

Refining Domain‐Based Prognostication in DNM1 Encephalopathy: A Mild Phenotype Associated With a GTPase Domain Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT DNM1 encephalopathy is a rare autosomal dominant genetic condition characterized by a range of neurological and developmental manifestations. The typical phenotype is severe, including profound intellectual disability, treatment‐resistant epilepsy, ataxia, and structural brain abnormalities. However, milder presentations have increasingly been
Caroline Crain, Hope Northrup, Laura S. Farach, Sureni V. Mullegama, Kathleen Shields, Gretchen Von Allmen, Kate Richardson   +6 more
wiley   +1 more source