Results 151 to 160 of about 4,213 (269)

Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy [PDF]

open access: bronze, 2010
Pingguo Chen   +7 more
openalex   +1 more source

Inpatient vaginal dinoprostone vs outpatient balloon catheters for cervical ripening in induction of labor: An individual participant data meta‐analysis of randomized controlled trials

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Cervical ripening in the induction of labor with outpatient balloon catheters is probably less effective than inpatient vaginal dinoprostone, specifically in maternal overweight and obesity during pregnancy. The perinatal and maternal safety profiles are comparable.
Fei Chan   +9 more
wiley   +1 more source

The potential for therapeutic drug monitoring of belatacept and other biologicals in solid organ transplantation

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract In solid organ transplantation (SOT), biologicals such as recombinant therapeutic proteins, monoclonal antibodies, fusion proteins and conjugates are increasingly used for immunosuppression, desensitization, ABO (blood group) incompatibility, antibody‐mediated rejections and atypical haemolytic uremic syndrome.
Stein Bergan, Nils Tore Vethe
wiley   +1 more source

Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport [PDF]

open access: green, 2011
Yu Bai   +7 more
openalex   +1 more source

Pharmacokinetic characterization and exposure–response relationship of crovalimab in the COMMODORE 1, 2 and 3 and COMPOSER trials of patients with paroxysmal nocturnal haemoglobinuria

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Crovalimab is a novel C5 inhibitor administered first intravenously and then subcutaneously in patients with paroxysmal nocturnal haemoglobinuria (PNH) naive to complement inhibition or switching from eculizumab or ravulizumab. Crovalimab showed efficacy and safety comparable to eculizumab in the pivotal COMMODORE 2 and supporting studies.
Valérie Cosson   +19 more
wiley   +1 more source

TReND: Transformer derived features and Regularized NMF for neonatal functional network Delineation [PDF]

open access: yesarXiv
Precise parcellation of functional networks (FNs) of early developing human brain is the fundamental basis for identifying biomarker of developmental disorders and understanding functional development. Resting-state fMRI (rs-fMRI) enables in vivo exploration of functional changes, but adult FN parcellations cannot be directly applied to the neonates ...
arxiv  

Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and high‐throughput RNA sequencing

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Nimodipine, an L‐type voltage‐gated calcium channel blocker, is an approved cerebral vasorelaxant. We hypothesized that nimodipine attenuates the pro‐inflammatory shift in microglial phenotypes. Here, we analysed the effects of nimodipine on morphological and functional microglial phenotypes as well as their transcriptomic ...
István Pesti   +10 more
wiley   +1 more source

Characterization and Localization of the Neonatal Fc Receptor in Adult Human Kidney

open access: bronze, 2000
Jean‐Philippe Haymann   +8 more
openalex   +1 more source

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