Results 161 to 170 of about 55,479 (259)

Midwifery Students' Definitions of Normal Labor and Birth: A Study From Five Countries

open access: yesBirth, EarlyView.
The image brings together the seven aspects considered most important in defining ‘normal/physiological birth’ according to research carried out among 664 student midwives across five countries. ABSTRACT Introduction Internationally, many women and birthing people are receiving maternity care interventions as a routine with no medical indication for ...
International Network Exploring Midwifery Students' Confidence in Physiological Birth   +12 more
wiley   +1 more source

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

open access: yesBrain Pathology, EarlyView.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma   +12 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja   +11 more
wiley   +1 more source

Functionalized zein nanoparticles targeting neonatal Fc receptor to enhance lung absorption of peptides. [PDF]

open access: yesDrug Deliv Transl Res, 2023
Hameedat F   +4 more
europepmc   +1 more source

Safer Access With Fewer Transfusions: Revisiting Platelet Thresholds in Pediatric Central Venous Catheterization

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Central venous catheters (CVCs) are essential in pediatric hematology‐oncology, for the administration of chemotherapy and supportive therapy. Thrombocytopenia increases the risk of bleeding and current guidelines recommend prophylactic platelet transfusions below 40–50 × 109/L, though evidence is limited and transfusions entail ...
Alessandro Raffaele   +8 more
wiley   +1 more source

The Neonatal Fc Receptor Is Elevated in Monocyte-Derived Immune Cells in Pancreatic Cancer. [PDF]

open access: yesInt J Mol Sci, 2022
Thomas J   +20 more
europepmc   +1 more source

An update on the landscape of collagen bioactive fragments

open access: yesThe FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Home - About - Disclaimer - Privacy