Results 151 to 160 of about 1,686,776 (208)

Developmental Toxicity Study for the Antimalarial Drug Combination Cabamiquine‐Pyronaridine Using a Translational Approach

Birth Defects Research, Volume 118, Issue 10, October 2026.
ABSTRACT Background The safety of pharmacological treatments during pregnancy is a significant concern, as many medications lack comprehensive reproductive safety data. This creates gaps in therapeutic options for pregnant women, particularly malaria, which poses serious risks to maternal and fetal health.
Wookyung Kim, Geum‐Sil Cho, Andreas Gado, Tobias Hyun Ho Baeurle, Habib Karimi, Filippo Venezia, Claude Oeuvray, Thomas Spangenberg, Sebastian G. Wicha, Claudia Demarta‐Gatsi   +9 more
wiley   +1 more source

Recurrent steroid-intolerant Hashimoto's encephalopathy responsive to single-dose neonatal Fc receptor antagonist: a case report and literature review. [PDF]

BMC Neurol
Wang X, Wang G, Xu J, Bai Y, Yan W, Liu X, Zhang S, Shen R.   +7 more
europepmc   +1 more source

Current advances in 2025: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee

Transfusion, EarlyView.
Nabiha H. Saifee, Jennifer Andrews, Mary Berg, Stella T. Chou, Mischa Covington, Elizabeth P. Crowe, Ruchika Goel, Juliana A. Guarente, Tina Ipe, Jeremy W. Jacobs, Jessica Jacobson, Cyril Jacquot, Jenna Khan, Thane A. Kubik, Theodros Mamo, Michael F. Murphy, Kerry O'Brien, Monica B. Pagano, Anil K. Panigrahi, Jacqueline N. Poston, Scott E. Potter, Simon J. Stanworth, Moritz Stolla, Alyssa Ziman, Ryan A. Metcalf   +24 more
wiley   +1 more source

Peripartum Management of Vagus Nerve Stimulation and Antiseizure Medications During Two Pregnancies in a Woman With Drug‐Resistant Epilepsy: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT There are limited reports on vagus nerve stimulation (VNS) therapy during pregnancy. We report a case of two pregnancies in a woman with drug‐resistant epilepsy (DRE) managed with VNS. A woman with epilepsy underwent implantation of a VNS device because antiseizure medications (ASMs) and a lobectomy were not sufficient to control seizures ...
Motoki Ono, Ryoichi Asaka, Yasuhiro Tanaka, Chiho Fuseya, Norihiko Kikuchi, Tsutomu Miyamoto   +5 more
wiley   +1 more source

Dynamics of intracellular neonatal Fc receptor-ligand interactions in primary macrophages using biophysical fluorescence techniques. [PDF]

Mol Biol Cell, 2022
Pannek A, Houghton FJ, Verhagen AM, Dower SK, Hinde E, Gleeson PA.   +5 more
europepmc   +1 more source

Long Term Follow Up of Hereditary Thrombotic Thrombocytopenic Purpura on Plasma Therapy for 9 Years: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 7.6‐year‐old boy with hTTP had fever‐induced hemorrhagic rash, MAHA, cerebral infarction, and renal impairment. After plasma therapy, symptoms were partially relieved; 9‐year follow‐up showed regular plasma transfusion was needed, with CKD Stage 3.
Dai Xiaomei, Chen Ruyue, Wu Shuang, Tang Hanyun, Lin Qiang, Li Xiaozhong   +5 more
wiley   +1 more source

Safety and Efficacy of a Neonatal Fc Receptor Antagonist in Patients With Anti-NMDAR Encephalitis. [PDF]

CNS Neurosci Ther
Bian Z, Cai H, Wu H, Liu P, Zuo Y, Peng F, Qiu W, Lu Z, Zhang B.   +8 more
europepmc   +1 more source

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults

Clinical Pharmacology in Drug Development, Volume 15, Issue 10, October 2026.
Abstract REGN17092, a fully human immunoglobulin (Ig) G1 antibody with M252Y/S254T/T256E (YTE) modification in the Fc portion, was assessed in a first‐in‐human study (ClinicalTrials.gov, NCT05923424). REGN17092 was designed to target the severe acute respiratory coronavirus 2 (SARS‐CoV‐2) S protein.
Maria Rosario, Jan de Hoon, Flonza Isa, Kenneth Turner, Jing Li, Joel Kantrowitz, Samit Ganguly, Sasha Fraser, Zhongqing Will He, Hong Yan, Ana Gonzalez Ortiz, Lori Faria, Ingeborg Heirman, Alina Baum, Thomas D Norton, Yogesh Patel, Veronica Mas Casullo, John D Davis   +17 more
wiley   +1 more source

Blocking the neonatal Fc receptor as a novel approach to prevent cardiac neonatal lupus: a proof-of-concept study. [PDF]

Ann Rheum Dis
Carlucci PM, Masson M, Cuneo BF, Brandt JS, Worthing AB, Izmirly P, Fraser N, Sachan N, Donofrio MT, Clancy R, Buyon JP.   +10 more
europepmc   +1 more source

Deciphering the Interaction between Neonatal Fc Receptor and Antibodies Using a Homogeneous Bioluminescent Immunoassay. [PDF]

J Immunol, 2021
Nath N, Godat B, Flemming R, Urh M.
europepmc   +1 more source