Results 151 to 160 of about 55,479 (259)

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

Fc-empowered exosomes with superior epithelial layer transmission and lung distribution ability for pulmonary vaccination

Bioactive Materials
Mucosal vaccines offer potential benefits over parenteral vaccines for they can trigger both systemic immune protection and immune responses at the predominant sites of pathogen infection.
Fan Meng, Haonan Xing, Jingru Li, Yingqi Liu, Li Tang, Zehong Chen, Xiran Jia, Zenglin Yin, Jing Yi, Mei Lu, Xiuli Gao, Aiping Zheng   +11 more
doaj   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Case report: Rapid symptom relief in autoimmune encephalitis with efgartigimod: a three-patient case series

Frontiers in Immunology
IntroductionAutoimmune encephalitis (AE) comprises a group of inflammatory brain disorders mediated by autoimmune responses. Anti–N-methyl-D-aspartate receptor (NMDAR) encephalitis, anti–leucine-rich glioma-inactivated 1 (LGI1) encephalitis, and anti–γ ...
Qianqian Zhang, Wenping Yang, Yun Qian, Yu Zhang, Huihui Zhao, Mingzhu Shu, Qingyang Li, Yanan Li, Yu Ding, Shiyu Shi, Yaxi Liu, Xi Cheng, Qi Niu   +12 more
doaj   +1 more source

Transport of antibody into the skin is only partially dependent upon the neonatal Fc-receptor. [PDF]

PLoS One, 2023
Nasir G, Sinnis P.
europepmc   +1 more source

Early Maturation of Heart Rate Variability in Very Preterm Infants Depends on Neonatal Factors and Is Associated With Neurodevelopmental Risk

Acta Paediatrica, EarlyView.
ABSTRACT Aim This study investigated central autonomic network maturation deviations using a previously defined machine learning model set to estimate a functional maturation age (FMA) from heart rate variability (HRV) analysis. We investigated whether these deviations were associated with maternal, fetal, perinatal, or postnatal complications and with
Léa Bonneau, Cyril Flamant, Maxime Esvan, Jean Michel Roué, Géraldine Favrais, Géraldine Gascoin, Sandie Cabon, Fabienne Porée, Guy Carrault, Patrick Pladys   +9 more
wiley   +1 more source

The Role of Inflammation in Infant Colic—A Systematic Review and Meta‐Analysis

Acta Paediatrica, EarlyView.
ABSTRACT Aim Despite being a self‐limiting condition, infant colic is associated with negative consequences for caregivers and infants. Gut inflammation is hypothesised as a contributing factor. We collected and meta‐analysed the most recent evidence on the association between infant colic and gut inflammation.
Dan Boëtius Andersen, Julius Fog, Marie V. Vestergaard, Ida Scheel Rasmussen, Philip Wilson, Gritt Overbeck, Louise Bidstrup Jørgensen, Jakob Kragstrup, Betina Hebbelstrup Jensen   +8 more
wiley   +1 more source

Comparing Fenton and INTERGROWTH‐21st Growth Charts in Assessing Preterm Infant Growth Below 33 Weeks' Gestation

Pediatric Discovery, EarlyView.
Vitor dos Santos Andrade, Juliana Dantas de Araújo Santos Camargo, Sávio Ferreira Camargo, Amanda Karoline da Costa Bezerra, Raionara Cristina de Araújo Santos, Cijara Leonice de Freitas, Camiliane Azevedo Ferreira, Ricardo Ney Cobucci, Claudia Rodrigues Souza Maia   +8 more
wiley   +1 more source

Bowel Habits and Functional Constipation in Healthy Children—A Longitudinal Birth‐Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim Functional constipation is common during childhood. Parents' concerns about their child's bowel habits are often the reason for seeking healthcare. We aim to report data on normal bowel habits, prevalence of functional constipation, long‐term outcome, and a search for risk factors in children during the first 2.5 years of life.
C. Gatzinsky, U. Sillén, M. Bräutigam, C. Kullberg‐Lindh, S. Thornberg, S. Sjöström   +5 more
wiley   +1 more source

Benefits and Harms of Antenatal/Intrapartum Screening for Maternal Group B Streptococcus and Use of Intrapartum Antibiotic Prophylaxis Versus Risk‐Based Protocols or No Intervention: A Rapid Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim To synthesise evidence on the effectiveness, harms and benefits of different approaches to prevent early‐onset Group B Streptococcus (EOGBS) and identify gaps in short and longer‐term outcomes. Methods A two‐phase rapid review. Phase 1 included an overview of systematic reviews (SRs).
Pauline Campbell, Cathryn Broderick, Candida Fenton, Bridget Davis, Wei Xu, Alex Todhunter‐Brown, Narendra Aladangady, Richard F. Chin, Rosie Hill, Ryan Kean, Charlotte‐Eve Short, Julie Cowie, NESSIE—NIHR Evidence Synthesis Scotland InitiativE   +12 more
wiley   +1 more source