Results 181 to 190 of about 1,686,776 (208)

The neonatal Fc receptor (FcRn) is required for porcine reproductive and respiratory syndrome virus uncoating. [PDF]

J Virol
Yang K, Dong J, Li J, Zhou R, Jia X, Sun Z, Zhang W, Li Z.   +7 more
europepmc   +1 more source

Cross-Species Extrapolation of Neonatal Fc Receptor (FcRn) Binding Affinity to Predict Monoclonal Antibody Pharmacokinetics in Humans Using Physiologically Based Pharmacokinetic Modeling (PBPK): Are We There Yet? [PDF]

ACS Pharmacol Transl Sci
Benamara S, Troisi C, Gattacceca F, Sjögren E, Nguyen L, Teutonico D.   +5 more
europepmc   +1 more source

Pharmacokinetics and Pharmacodynamics of Nipocalimab, a Neonatal Fc Receptor Blocker, in Healthy Japanese Volunteers. [PDF]

Clin Drug Investig
Matsushima N, Shibata S, Leu JH, Vermeulen A, Duffner J, Ling LE, Schwartz LB, Harigae H.   +7 more
europepmc   +1 more source

Current state and potential applications of neonatal Fc receptor (FcRn) inhibitors in hematologic conditions. [PDF]

Am J Hematol
Jacobs JW, Booth GS, Raza S, Clark LM, Fasano RM, Gavriilaki E, Abels EA, Binns TC, Duque MA, McQuilten ZK, Mingot-Castellano ME, Savani BN, Sharma D, Tran MH, Tormey CA, Moise KJ, Bloch EM, Adkins BD.   +17 more
europepmc   +1 more source

Dose Optimization of rhIL-7-hyFc for Patients With Lymphopenia Using a Neonatal Fc Receptor-Mediated Recycling-Based and Target-Mediated Drug Disposition Pharmacokinetic Model. [PDF]

Clin Transl Sci
Jeon HS, Lee SW, Jung W, Jung H, Choi D, Byun MS, Yun HY, Lee S, Kim A, Chae JW, Lee H.   +10 more
europepmc   +1 more source

Baicalein Ameliorates Experimental Ulcerative Colitis Recurrency by Downregulating Neonatal Fc Receptor via the NF-κB Signaling Pathway. [PDF]

ACS Omega
Hu H, Lu F, Guan X, Jiang X, Wen C, Wang L.   +5 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Neonatal Fc Receptor Inhibitor Rozanolixizumab: An Ethnic Sensitivity Study in Healthy Japanese, Chinese, and White Participants. [PDF]

Clin Pharmacol Drug Dev
El Baghdady A, Lledó-García R, Gayfieva M, Lowcock R, Watanabe S, Sidhu J, Wilkes D.   +6 more
europepmc   +1 more source

Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. [PDF]

MAbs
Schlein E, Andersson KG, Dallas T, Syvänen S, Sehlin D.   +4 more
europepmc   +1 more source

Association of the neonatal Fc receptor promoter variable number of tandem repeat polymorphism with immunoglobulin response in patients with chronic inflammatory demyelinating polyneuropathy. [PDF]

Eur J Neurol
Fisse AL, Schäfer E, Hieke A, Schröder M, Klimas R, Brünger J, Huckemann S, Grüter T, Sgodzai M, Schneider-Gold C, Gold R, Nguyen HP, Pitarokoili K, Motte J, Arning L.   +14 more
europepmc   +1 more source

Endocytotic Albumin Uptake Pathways in Human Adipose Stem Cells and Connection to Intracellular Calcium Oscillations and the Neonatal Fc receptor.

Cells Tissues Organs
Morshed MT, Bernhardt A, Wartenberg M, Sauer H.   +3 more
europepmc   +1 more source