Results 191 to 200 of about 55,479 (259)

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic, Boris Novakovic, Barbara Leopold‐Posch, Magdalena Mühlberger, Denise Hoch, Jelena Lögl, Eva M. Bernhart, Richard Saffery, Gernot Desoye, Ursula Hiden   +9 more
wiley   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

The Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford, Georgia Fakonti, Ziyu Shao, Sharanam Soni, Sophie L. Earle, Muath Bajarwan, Lara C. Morley, Beth Holder, Eleanor M. Scott, Karen Forbes   +9 more
wiley   +1 more source

Lack of neonatal Fc receptor does not diminish the efficacy of the HSV-1 0ΔNLS vaccine against ocular HSV-1 challenge. [PDF]

Vaccine, 2021
Carr DJJ, Berube AN, Filiberti A, Gmyrek GB.   +3 more
europepmc   +1 more source

Immunoglobulin G Levels in Yemeni Preterm Newborns: Infant Factors Predominate

Reproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Background IgG levels in preterm infants play a crucial role in response to infection and inflammation. Infectious disease burden in the low‐income countries, such as Yemen, exacerbates the problem. The preterm infant's IgG sources are either maternal or fetal immune system.
Antar F. A. M. Al‐Badani, Jamil M. A. S. Obaid, Safana M. H. Al‐Sofi, Rahma A. S. Al‐Mansoub   +3 more
wiley   +1 more source

Targeting the neonatal Fc receptor (FcRn) is not beneficial in an animal model of chronic neuritis. [PDF]

Immunol Res
Mausberg AK, Szepanowski F, Eggert B, Liebig KC, Kleinschnitz C, Kieseier BC, Stettner M.   +6 more
europepmc   +1 more source

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Comprehensive Review of Types, Pathophysiology, and Treatment Approaches

Brain and Behavior, Volume 16, Issue 5, May 2026.
Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan, Arsal Khan, Kuldeep Dalpat Rai, Anzel Saeed, Harsh Kumar, Aneesh Kumar Sangtiani, Tehreem Fatima, Muhammad Tanveer Alam, Faiza Rajput, Sakshi Chawla, Hussain Haider Shah, Humaira Kalam   +11 more
wiley   +1 more source

Reducing IgG accumulation via neonatal Fc receptor (FcRn) blockade relieves neuropathic pain. [PDF]

Brain Behav Immun
Fiore NT, Willcox KF, Dayani D, Zuberi YA, Heijnen CJ, Grace PM.   +5 more
europepmc   +1 more source

The Ubiquitin Ligase Zinc Finger SWIM Domain‐Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA‐7 Axis

Glia, Volume 74, Issue 5, May 2026.
ZSWIM8, an E3 ubiquitin ligase that broadly targets IDR‐rich proteins, drives MiR‐7‐dependent AGO2 degradation and the turnover of many RBPs. Loss of ZSWIM8 leads to MiR‐7 accumulation in oligodendrocyte progenitor cells and myelination defects in the developing brain. ABSTRACT Proteostasis of proteins with intrinsically disordered regions (IDRs) is of
Jing Lei, Siming Zhong, Rong Fan, Xin Shu, Guan Wang, Jiansheng Guo, Shuting Xue, Luqian Zheng, Aiming Ren, Junfang Ji, Bing Yang, Shumin Duan, Zhiping Wang, Xing Guo   +13 more
wiley   +1 more source

Microglial Inhibition Promotes Proliferation and Differentiation of Neural Stem Cells via STAT3/SDF‐1/CXCR4 Signaling Pathway in Hypoxic–Ischemic Encephalopathy

Glia, Volume 74, Issue 5, May 2026.
Partial microglial depletion indirectly promoted the activity of the STAT3 signaling pathway in neural cells and increased the proliferation and/or differentiation of NSCs in areas of infarction to exert neuroprotective effects via the paracrine effects of NSCs and immature neurons in HIE.
Ao Ding, Guiqin Duan, Mingwei Zhu, Li Chen, Jie Luo, Ting Tan, Zilin Li, Wenhui Wang, Jun Wang, Yuan Chen, Ya‐Ping Tang   +10 more
wiley   +1 more source

Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium. [PDF]

Bioact Mater, 2022
Martins JP, Figueiredo P, Wang S, Espo E, Celi E, Martins B, Kemell M, Moslova K, Mäkilä E, Salonen J, Kostiainen MA, Celia C, Cerullo V, Viitala T, Sarmento B, Hirvonen J, Santos HA.   +16 more
europepmc   +1 more source