Results 191 to 200 of about 4,213 (269)
Certolizumab pegol for plaque psoriasis in women of childbearing potential, pregnant or breastfeeding in clinical settings: One‐year outcomes from the international noninterventional CIMREAL study
Journal of the European Academy of Dermatology and Venereology, EarlyView.Tom Hillary, Fiona Lovegrove, Thierry Boye, Evangelia Papadavid, Luca Bianchi, Ángeles Flórez Menéndez, Alberto Barea, Frederik Fierens, Ines Dueñas Pousa, Jackie Hee, Paulette Williams, Khusru Asadullah +11 morewiley +1 more sourceTherapeutic hypothermia success for hypoxic‐ischaemic encephalopathy in Latin America: Eight‐year experience in EpicLatino Neonatal Network
Acta Paediatrica, Volume 114, Issue 5, Page 922-928, May 2025.Abstract Aim
A study reported that therapeutic hypothermia (TH) did not reduce the combined prognosis of mortality and disability at 18 months, in low‐ and middle‐income countries for patients with hypoxic ischaemic encephalopathy (HIE) who received TH, suggesting its no implementation in these regions.Carlos Fajardo, Marco Belzu, Manuel Bernal Benitez, Ángela Hoyos, Rubén Hernández Patiño, Luis Monterrosa, Carolina Villegas, EpicLatino Neonatal Network +7 morewiley +1 more sourceFc-empowered exosomes with superior epithelial layer transmission and lung distribution ability for pulmonary vaccination
Bioactive MaterialsMucosal vaccines offer potential benefits over parenteral vaccines for they can trigger both systemic immune protection and immune responses at the predominant sites of pathogen infection.Fan Meng, Haonan Xing, Jingru Li, Yingqi Liu, Li Tang, Zehong Chen, Xiran Jia, Zenglin Yin, Jing Yi, Mei Lu, Xiuli Gao, Aiping Zheng +11 moredoaj Protective immune response against Rhodococcus equi: An innate immunity‐focused review
Equine Veterinary Journal, Volume 57, Issue 3, Page 563-586, May 2025.Abstract
Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune Bibiana Petri da Silveira, Noah D. Cohen, Sara D. Lawhon, Robert O. Watson, Angela I. Bordin +4 morewiley +1 more sourceMaternal IgE Influence on Fetal and Infant Health
Immunological Reviews, Volume 331, Issue 1, May 2025.ABSTRACT
Immunoglobulin E (IgE) is the most recently discovered and evolved mammalian antibody type, best known for interacting with mast cells (MCs) as immune effectors. IgE‐mediated antigen sensing by MC provides protection from parasites, venomous animals, bacteria, and other insults to barrier tissues exposed to the environment.Jozef Balla, Abhay P. S. Rathore, Ashley L. St. John +2 morewiley +1 more sourceEuropean S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment
Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 899-941, May 2025.HS treatment algorithm. Abstract Introduction
This second part of the S2k guidelines is an update of the 2015 S1 European guidelines. Objective
These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS ...C. C. Zouboulis, F. G. Bechara, F. Benhadou, V. Bettoli, Z. Bukvić Mokos, V. Del Marmol, M. Dolenc‐Voljč, E. J. Giamarellos‐Bourboulis, Ø. Grimstad, P. Guillem, B. Horváth, R. E. Hunger, J. R. Ingram, D. Ioannidis, E. Just, L. Kemény, B. Kirby, A. I. Liakou, B. M. McGrath, A. V. Marzano, Ł. Matusiak, A. Molina‐Leyva, A. Nassif, M. Podda, E. P. Prens, F. Prignano, H. Raynal, M. Romanelli, D. M. L. Saunte, A. Szegedi, J. C. Szepietowski, T. Tzellos, S. Valiukevičienė, H. H. van der Zee, K. R. van Straalen, B. Villumsen, G. B. E. Jemec +36 morewiley +1 more sourceAdvances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases
Advanced Science, Volume 12, Issue 13, April 3, 2025.This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...Shuna Hou, Jiachen Yu, Yongshuang Li, Duoyi Zhao, Zhiyu Zhang +4 morewiley +1 more sourceCongenital Titinopathy: Comprehensive Characterization of the Most Severe End of the Disease Spectrum
Annals of Neurology, Volume 97, Issue 4, Page 611-628, April 2025.Congenital titinopathy has recently emerged as one of the most common congenital muscle disorders. Objective
To better understand the presentation and clinical needs of the under‐characterized extreme end of the congenital titinopathy severity spectrum.Sandra Coppens, Nicolas Deconinck, Patricia Sullivan, Andrei Smolnikov, Joshua S. Clayton, Kaitlyn R. Griffin, Kristi J. Jones, Catheline N. Vilain, Hazim Kadhim, Samantha J. Bryen, Fathimath Faiz, Leigh B. Waddell, Frances J. Evesson, Madhura Bakshi, Jason R. Pinner, Amanda Charlton, Susan Brammah, Nicole S. Graf, Michael Krivanek, Chee Geap Tay, Nicola C. Foulds, Marjorie A. Illingworth, Neil H. Thomas, Sian Ellard, Ingrid Mazanti, Soo‐Mi Park, Courtney E. French, Jennifer Brewster, Gusztav Belteki, Shazia Hoodbhoy, Kieren Allinson, Deepa Krishnakumar, Gareth Baynam, Bradley M. Wood, Michelle Ward, Kayal Vijayakumar, Amber Syed, Archana Murugan, Anirban Majumdar, Ingrid J. Scurr, Miranda P. Splitt, Corina Moldovan, Deepthi C. de Silva, Kumudu Senanayake, Thatjana Gardeitchik, Yvonne Arens, Sandra T. Cooper, Nigel G. Laing, F. Lucy Raymond, Heinz Jungbluth, Erik‐Jan Kamsteeg, Adnan Manzur, Susan M. Corley, Gianina Ravenscroft, Marc R. Wilkins, Mark J. Cowley, Mark Pinese, Titin Research Consortium, Ana Ferreiro, Isabelle Richard, Carsten G. Bönnemann, Sandra Donkervoort, Ho‐Ming Luk, Hugo Sampaio, Michelle A. Farrar, David Mowat, Robin B. Fitzsimons, Carole Vuillerot, Rahul Phadke, Mark R. Davis, Francesco Muntoni, Emily C. Oates +71 morewiley +1 more source