Pharmacokinetics and Pharmacodynamics of Nipocalimab, a Neonatal Fc Receptor Blocker, in Healthy Japanese Volunteers. [PDF]
Matsushima N +7 more
europepmc +1 more source
Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis. [PDF]
Dylewski JF +4 more
europepmc +1 more source
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Neonatal Fc Receptor Inhibitor Rozanolixizumab: An Ethnic Sensitivity Study in Healthy Japanese, Chinese, and White Participants. [PDF]
El Baghdady A +6 more
europepmc +1 more source
Quality of Life in Chronic Heart Failure With Obstructive Sleep Apnea: A Systematic Review
ABSTRACT Aim To describe the quality of life in patients with chronic heart failure and coexisting obstructive sleep apnoea, and to examine the effect of common sleep‐disordered breathing treatments on quality of life, functional capacity and cardiac outcomes. Design Systematic review.
Francesco Limonti +7 more
wiley +1 more source
ABSTRACT Background The optimal methods and settings for induction of labour (IOL) in terms of effectiveness, safety, and women's experience are still not elucidated. Objective To compare the effectiveness and safety of outpatient versus inpatient cervical ripening settings for IOL. Search Strategy MEDLINE, Embase, Emcare, CINAHL Plus, Scopus, Cochrane
Malitha Patabendige +22 more
wiley +1 more source
ABSTRACT Background and Aim Alagille syndrome (ALGS) is a rare disorder characterised by cholestasis and extrahepatic manifestations. Given the current era of ileal bile acid transporter (IBAT) inhibitor therapies that reduce serum bile acid (SBA) levels, we evaluated whether SBA predicts liver disease outcomes in ALGS.
Carla Fiorella Murillo Perez +97 more
wiley +1 more source
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. [PDF]
Schlein E +4 more
europepmc +1 more source
Treatment with anti-neonatal Fc receptor (FcRn) antibody ameliorates experimental epidermolysis bullosa acquisita in mice. [PDF]
Kasprick A +7 more
europepmc +1 more source
Abstract Introduction Joint‐ill in neonatal lambs, primarily caused by Streptococcus dysgalactiae subspecies dysgalactiae (SDSD), results in increased mortality and morbidity. An effective vaccine is needed to prevent the disease. Methods A blinded randomised controlled trial was carried out using an autologous SDSD vaccine in a commercial sheep flock ...
Joseph W. Angell +5 more
wiley +1 more source
Association of the neonatal Fc receptor promoter variable number of tandem repeat polymorphism with immunoglobulin response in patients with chronic inflammatory demyelinating polyneuropathy. [PDF]
Fisse AL +14 more
europepmc +1 more source

