Results 71 to 80 of about 897,682 (280)

Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma

Scientific Reports, 2016
Melanoma is a highly malignant neoplasm of melanocytes with considerable metastatic potential and drug resistance, explaining the need for new candidates that inhibit tumor growth and metastasis. The signal transducer and activator of the transcription 3
Yongxia Zhu, Tinghong Ye, Xi Yu, Qian Lei, Fangfang Yang, Yong Xia, Xuejiao Song, Li Liu, H. Deng, Tiantao Gao, Cuiting Peng, Weiqiong Zuo, Ying Xiong, Lidan Zhang, Ningyu Wang, Lifeng Zhao, Yongmei Xie, Luoting Yu, Yuquan Wei   +18 more
semanticscholar   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

DEP domain containing 1 predicts prognosis of hepatocellular carcinoma patients and regulates tumor proliferation and metastasis

Cancer Science, 2018
DEP domain containing 1 (DEPDC1) protein is a novel oncoantigen upregulated in multiple types of cancers which present oncogenic activity and high immunogenicity. However, the function and therapeutic potential of DEPDC1 in hepatocellular carcinoma (HCC)
D. Qu, F. Cui, D. Lu, Yu Yang, Yuqing Xu
semanticscholar   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Development and comparison of novel bioluminescent mouse models of pancreatic neuroendocrine neoplasm metastasis. [PDF]

Sci Rep, 2021
Kaemmer CA, Umesalma S, Maharjan CK, Moose DL, Narla G, Mott SL, Zamba GKD, Breheny P, Darbro BW, Bellizzi AM, Henry MD, Quelle DE.   +11 more
europepmc   +1 more source

Bilateral choroidal metastasis from carcinoma of the submandibular gland

Indian Journal of Ophthalmology, 2008
Metastatic tumor is the most common uveal malignancy. However, choroidal metastasis from a salivary gland neoplasm is extremely rare. We report a case of bilateral, multifocal choroidal metastasis from carcinoma of the submandibular gland.
John Sheeja, Horo Saban, Braganza Andrew, Kuriakose Thomas   +3 more
doaj  

Descoberta simultânea de carcinomatose disseminada e carcinoma de cólon, após colecistectomia laparoscópica

Revista do Colégio Brasileiro de Cirurgiões
A particularly rapid and fatal outcome has been noted in cases of malignant soft-tissue metastases occurring after cancer surgery. Abdominal wall metastases occurring in scars after laparotomy for cancer resection show a similar poor outcome.
João Luiz M. C. Azevedo, Délcio Mattos, Otávio Azevedo   +2 more
doaj   +1 more source

EVALUATION OF LYMPHATIC SPREAD, VISCERAL METASTASIS AND TUMORAL LOCAL INVASION IN ESOPHAGEAL CARCINOMAS

ABCD: Arquivos Brasileiros de Cirurgia Digestiva, 2016
Background: Knowing esophageal tumors behavior in relationship to lymph node involvement, distant metastases and local tumor invasion is of paramount importance for the best esophageal tumors management.
Francisco TUSTUMI, Cintia Mayumi Sakurai KIMURA, Flavio Roberto TAKEDA, Rubens Antônio Aissar SALLUM, Ulysses RIBEIRO-JUNIOR, Ivan CECCONELLO   +5 more
doaj   +2 more sources

miR-206 inhibits metastasis-relevant traits by degrading MRTF-A in anaplastic thyroid cancer.

International Journal of Oncology, 2015
Thyroid cancer develops from follicular or parafollicular thyroid cells. A higher proportion of anaplastic thyroid cancer has an adverse prognosis. New drugs are being used in clinical treatment.
Wen-long Zhang, W. Lv, Suo-zhu Sun, Xi-Zhao Wu, Jian-hua Zhang   +4 more
semanticscholar   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source