The relationship of site to transplantability [PDF]
Thesis (M.A.)--Boston ...
Anderson, Leonard L.
core
MicroRNAs Implicated in Dysregulation of Gene Expression Following Human Lung Transplantation [PDF]
Lung transplantation remains the only viable treatment option for the majority of patients with advanced lung diseases. However, 5-year post-transplant survival rates remain low primarily secondary to chronic rejection. Novel insights from global gene expression profiles may provide molecular phenotypes and therapeutic targets to improve outcomes after
arxiv +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Brain and bone metastasis of hepatocellular carcinoma after a liver transplantation – Case report
Liver transplantation has improved the disease-free survival of patients with hepatocellular carcinoma, although local tumor recurrence, and less often extra hepatic metastasis are a possible outcome.
Ilka de Fátima Santana Ferreira Boin+3 more
doaj +1 more source
Allogeneic Hematopoietic Stem Cell Transplantation in a Rare Case of Tonsillar Mast Cell Sarcoma
Mast cell sarcoma comprises a rare aggressive mast cell neoplasia with histological, clinical, and genetic features distinct from other mast cell neoplasm.
Anne Sophie Kubasch+10 more
doaj +1 more source
Immunotherapy for hepatocellular carcinoma in liver transplant patients (Literature review)
Hepatocellular carcinoma (HCC) is the third cause of cancer-related mortality worldwide, accounting for more than 800,000 deaths annually. Surgical removal of the neoplasm remains the most effective treatment option.
I. A. Dzhanyan+9 more
doaj +1 more source
Cutaneous and mucosal neoplasms in bone marrow transplant recipients [PDF]
Fifty-six long-term survivors of bone marrow allografts were followed for a minimum of 40 months after bone marrow transplantation (BMT) to determine the frequency of secondary malignancies. The 56 patients included ten with severe aplastic anemia (SAA), 16 with acute myeloblastic leukemia (AML), 11 with acute lymphoblastic leukemia (ALL), and 19 with ...
B. Patterson+7 more
openaire +3 more sources
Interplay of integrins and selectins in metastasis
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva+2 more
wiley +1 more source
Subsequent Malignant Neoplasms after Hematopoietic Cell Transplantation
Subsequent malignant neoplasms (SMNs) developing after hematopoietic cell transplantation (HCT) are a well-described complication (1–6). The magnitude of risk of SMNs after HCT ranges from 4-fold to 11-fold that of the general population. The estimated actuarial incidence is reported to be 3.5% at 10 years, increasing to 12.8% at 15 years among ...
Smita Bhatia+2 more
openaire +3 more sources
Regime and Treatment Effects in Duration Models: Decomposing Expectation and Transplant Effects on the Kidney Waitlist [PDF]
This paper proposes a causal decomposition framework for settings in which an initial regime randomization influences the timing of a treatment duration. The initial randomization and treatment affect in turn a duration outcome of interest. Our empirical application considers the survival of individuals on the kidney transplant waitlist.
arxiv