Results 91 to 100 of about 340,830 (293)

P632: ORAL AND GUT MICROBIAL DIVERSITY CORRELATES WITH PROGNOSTIC FEATURES IN CHRONIC LYMPHOCYTIC LEUKEMIA

HemaSphere, 2022
M. Szelest, M. Paziewska, M. Kiełbus, M. Masternak, J. Zaleska, E. Wawrzyniak, E. Kalicińska, P. Jabłonowska, T. Wróbel, A. Wolska-Washer, J. Z. Błoński, K. Giannopoulos   +11 more
doaj   +1 more source

NPCMF: Nearest Profile-based Collaborative Matrix Factorization method for predicting miRNA-disease associations

BMC Bioinformatics, 2019
Background Predicting meaningful miRNA-disease associations (MDAs) is costly. Therefore, an increasing number of researchers are beginning to focus on methods to predict potential MDAs.
Ying-Lian Gao, Zhen Cui, Jin-Xing Liu, Juan Wang, Chun-Hou Zheng   +4 more
doaj   +1 more source

Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with carcinogenesis [PDF]

, 2006
Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several investigations support the view that common fragile sites play a role in carcinogenesis.
A Caputo, A Matsuyama, A Musio, Alda Maria Puliti, AM Casper, Angela Re, CD Hou, CT Miller, D Corà, D Corà, D Iliopoulos, Davide Cora, E Birney, H Ishii, I Sbrana, I Sbrana, Isabella Sbrana, ISCN, J Bartkova, J Hoshen, K Mimori, KA Cimprich, KA Nyberg, LV O'Keefe, M Ashburner, M Fabbri, M Schwartz, Michele Caselle, Newman MEJ, NS Chang, P Hoglund, RS Cha, S Corbin, S Gasser, SL Reiner, T Oyama, TW Glover, U Krummrei, VG Gorgoulis, Y Zhu   +39 more
core   +5 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

P1258: MOLECULAR CYTOGENETICS CHARACTERIZATION OF CLASSICAL HODGKIN LYMPHOMA. ROL OF 9P24.1 (PD-L1/PD-L2) POLYSOMIES

HemaSphere, 2022
M. García-Montenegro, M. Narbaitz, M. F. Metrebian, A. Pavlovsky, I. Slavutsky   +4 more
doaj   +1 more source

Hypothesis of the basic biological sense of cancer revisited: a putative explanation of Peto's paradox [PDF]

, 2017
The conventional interpretation of cancer, summarized in the unified genetic theory of carcinogenesis, assumes that the malignant cell is the anatomical and physiological unit of cancer.
Bustuoabad, Oscar David, Ruggiero, Raul Alejandro   +1 more
core  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Mutations and thrombosis in essential thrombocythemia

Blood Cancer Journal, 2021
Paola Guglielmelli, Naseema Gangat, Giacomo Coltro, Terra L. Lasho, Giuseppe Gaetano Loscocco, Christy M. Finke, Erika Morsia, Benedetta Sordi, Natasha Szuber, Curtis A. Hanson, Animesh Pardanani, Alessandro M. Vannucchi, Ayalew Tefferi   +12 more
doaj   +1 more source

PB1915: THE MULTI-FACETED ROLE OF ORAL AND GUT MICROBIOME IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA

HemaSphere, 2023
Magdalena Paziewska, Monika Szelest, Joanna Zaleska, Michal Kielbus, Marta Masternak, Ewa Wawrzyniak, Aleksandra Kotkowska, Monika Siemieniuk-Ryś, Marta Morawska, Elzbieta Kalicinska, Paula Jabłonowska, Tomasz Wróbel, Anna Wolska-Washer, Jerzy Błoński, Krzysztof Giannopoulos   +14 more
doaj   +1 more source