Results 71 to 80 of about 6,505,244 (310)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Índice de los trabajos publicados en los números del 1 al 6 de Cine experimental [PDF]

, 1945
Cine experimental (1945). Índice de los trabajos publicados en los números del 1 al 6 de Cine experimental.
Cine experimental
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Journal of Multivariate Experimental Personality and Clinical Psychology, First Number, v.1, no.1 (complete version) 

, 1973
The first issue of the Journal of Multivariate Experimental Personality and Clinical Psychology edited by G.R. Pierson. Editorial policy board: Raymond B. Cattell, Hans J. Eysenck, Joy P. Guilford and Paul E. Meehl.Digitized and published in SOAR:Shocker
Western Institute of Multivariate Experimental Psychology
core   +1 more source

Effect of colostomy on experimentally produced neoplasms of the colon of the rat [PDF]

Cancer, 1967
As a means of determining the effect of the fecal stream in the pathogenesis of experimentally produced colonic tumors in Wistar strain rats, simple colostomies were performed in the left colon of 57 female rats at approximately 4 cm above the anus. Fifty-four rats received daily subcutaneous injections, 5 days per week, of the carcinogen 3:2'dimethyl ...
A, Navarrete, H J, Spjut
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Journal of Multivariate Experimental Personality and Clinical Psychology, v.1, no.3 (complete version)

, 1975
The third issue of the Journal of Multivariate Experimental Personality and Clinical Psychology edited by G.R. Pierson. Editorial policy board: R.B. Cattell, H.J. Eysenck, J.P. Guilford and P.E.

core   +1 more source

Rat mammary carcinogenesis following neutron- or X-radiation [PDF]

, 1974
Female 61 to 63 - day - old Sprague-Dawley rats were exposed once to a single dose of either 0.43 - MeV neutrons or 250 - kVX - rays . For neutrons 23 rats were exposed in plastic tubes rotated around and 31 c m from a water-cooled tritium impregnated ...
Rossi, H. H., Mills, R. E., Kellerer, Albrecht M., Goodman, L. J., Rao, A. R., Bond, V. P., Brown, R. D., Shellabarger, C. J., Shanley, J. P.   +8 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source