Results 81 to 90 of about 574,487 (311)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Mathematical modeling of tumor growth and treatment [PDF]
, 2014 Using mathematical models to simulate dynamic biological processes has a long history. Over the past couple of decades or so, quantitative approaches have also made their way into cancer research.
Chaplain, Mark A. J., Enderling, Heiko
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The role of α-acidic glycoprotein in formation of bleeding abnormalities in patients with myeloproliferative neoplasms [PDF]
, 2014 Aim: To compare glycoforms of alpha-acid glycoprotein (AGP) in myeloproliferative neoplasms (MPN) with hepatic lesions. Materials and Methods: 110 patients with MPN (31 with polycythaemia vera (PV), 75 with primary myelofibrosis (PMF), 4 with essential ...
Nikolaenko-Kamyshova, T.P.
core
HaematologicaBackground: Myelofibrosis (MF) is the most symptomatic form of MPN and carries the worst outcome. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and systemic inflammation response index
G. Capecchi +9 more
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Clinical Application and Advances in Radiofrequency Ablation of Lung Neoplasms [PDF]
, 2010 Lung cancer is the leading cause of cancer-related mortality worldwide. In recent years, radiofrequency ablation (RFA), as a minimally invasive therapy, has been increasing utilized as a non-surgical treatment option for patients with primary and ...
Yong ZHANG, Xiaoqun LI
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HaematologicaBackground Mild BM fibrosis (MF-1) can be identified in up to 20% of patients (pts) with polycythemia vera (PV) and essential thrombocytemia (ET), and may play a role –albeit still poorly defined–in pathophysiology, clinical presentation ad long-term ...
G. Coltro +6 more
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Raman Spectroscopy in Optical Non-Invasive Diagnostics of Skin Neoplasms
Креативная хирургия и онкологияIntroduction. Recent decades indicate a significant increase in the incidence of skin cancer. Aim. To upgrade the specialized device and to improve the quality of skin neoplasm diagnostics. Materials and methods.
O. I. Kaganov +6 more
doaj +1 more source