Results 111 to 120 of about 9,124 (231)
Background: Treatment of choice for patients with refractory germ cell tumors (GCT) or recurrence after platinum containing chemotherapy regimens is not yet well recognized.
Seied Asadollah Mousavi +8 more
doaj
Single‐cell and spatial analysis revealed distinct CRC microenvironments by tumour laterality. Right‐sided tumours showed enhanced germinal centre B cells, CXCL13+ T cells, and organized TLS‐immune crosstalk via CCL19/21‐CCR7, suggesting better immunotherapy response.
Zongnai Zhang +8 more
wiley +1 more source
CD30 antigen in embryonal carcinoma and embryogenesis and release of the soluble molecule
The expression, serological detection, and possible functional role of the CD30 antigen in Hodgkin's disease and anaplastic large cell lymphoma is well documented.
F. Eitelbach +8 more
core +1 more source
Wt1 expressed in the MD mesenchyme promotes MD regression by inducing Wif1 and Osx transcription. In male mice, mesenchyme‐specific inactivation of Wt1 results in MD retention. ABSTRACT In mammals, Müllerian ducts (MDs) are the precursors of the female reproductive tract which regress in males during embryonic development.
Min Chen +12 more
wiley +1 more source
The human germ cell lineage: pluripotency, tumourigenesis and proliferation
EThOS - Electronic Theses Online ServiceGBUnited ...
Perrett, Rebecca Mary
core +2 more sources
Chromosomes and Expression in Human Testicular Germ‐Cell Tumors
Human germ-cell tumors (GCTs) are a heterogeneous group of neoplasms. Based on epidemiology, anatomical site of presentation, histology, chromosomal constitution, and pattern of genomic imprinting, GCTs are classified into five entities.
LEENDERT H. J. LOOIJENGA +9 more
core +1 more source
Liver Organoids: From Disease Modelling to Regenerative Medicine
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang +5 more
wiley +1 more source
Lipoprotein lipase and endothelial lipase in human testis and in germ cell neoplasms
The aim of this study was to investigate endothelial lipase (EL, LIPG) and lipoprotein lipase (LPL) mRNA and protein expression in normal human testis and testicular germ cell tumours (GCT).
Nielsen, J E +13 more
core +1 more source
Ploidy‐Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells
Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Guy Haim‐Abadi, Nissim Benvenisty
wiley +1 more source
Expression of candidate biomarkers in human testicular germ cell tumor
Tumori zametnih stanica testisa (TGCT, od eng. testicular germ cell tumor) su heterogena skupina neoplazmi koja se dijeli na seminome i neseminome. Često se javljaju kao miješani tumori zametnih stanica.
Vanjorek, Vedran
core

