Results 131 to 140 of about 8,661 (199)

Zebrafish as an Anti‐Isogenic Vertebrate Model and What It Reveals About Genetic Background and Reproducibility

open access: yesBioEssays, Volume 48, Issue 6, June 2026.
Zebrafish illustrates how polygenic sex determination, maternal germline bottlenecks, and a structurally restless genome jointly destabilize deep homozygosity. These interlocking constraints make fully isogenic zebrafish lines effectively unattainable, turning this model into a natural “stress test” for assumptions about genetic background and ...
Álvaro J. Arana, Laura Sánchez
wiley   +1 more source

Stage IIIC Bilateral Dysgerminoma in a 16‐Year‐Old Phenotypic Female With 46,XY Complete Gonadal Dysgenesis and Primary Amenorrhea: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Dysgerminoma, the most common malignant ovarian germ cell tumor, has a significantly increased incidence in individuals with 46,XY complete gonadal dysgenesis (Swyer syndrome). However, primary amenorrhea is the hallmark presentation of Swyer syndrome in adolescence.
Mahshid Vasef   +4 more
wiley   +1 more source

Clinicopathological Features, Treatment Patterns, and Long‐Term Survival in Patients With Testicular Cancer: A Retrospective Cohort Study

open access: yesCancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Testicular cancer represents the most common solid tumor in young adult males and is associated with excellent long‐term survival outcomes. Aim The aim of this study is to evaluate clinical and pathological characteristics, treatment strategies, and survival outcomes of a large Romanian institutional cohort.
Emanuiela Florentina Rohozneanu   +2 more
wiley   +1 more source

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development

open access: yesComprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu   +6 more
wiley   +1 more source

Talin1 is downregulated in testicular germ cell tumors according to combined bioinformatics and experimental approaches. [PDF]

open access: yesSci Rep
Razmi M   +7 more
europepmc   +1 more source

Development and functional adaptation of intestinal macrophages across the lifespan

open access: yesClinical &Translational Immunology, Volume 15, Issue 6, 2026.
This article discusses intestinal macrophage development, including the influence of developmental origins and life stages; ontogeny and functional heterogeneity; preclinical and clinical evidence. Abstract Macrophages of the gastrointestinal system are central regulators of gut development, homeostasis and disease, yet their origin, functional ...
Baha Mustafa   +2 more
wiley   +1 more source

Generation and Characterization of Twist1 Acetyl‐Mimic and Acetyl‐Deficient Mouse Models

open access: yesgenesis, Volume 64, Issue 3, June 2026.
ABSTRACT TWIST1 encodes a highly conserved basic helix–loop–helix transcription factor essential for embryonic development from Drosophila to humans. TWIST1 activity is regulated by post‐translational modifications, including phosphorylation during development and cancer metastasis. Recent cancer studies identified acetylation of lysines K73 and K76 as
Mary Elmeniawi   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy