Clinical Features of Malignant Ovarian Germ Cell Tumors According to Demographic and Pathologic Characteristics. [PDF]
Agah J +3 more
europepmc +1 more source
Zebrafish illustrates how polygenic sex determination, maternal germline bottlenecks, and a structurally restless genome jointly destabilize deep homozygosity. These interlocking constraints make fully isogenic zebrafish lines effectively unattainable, turning this model into a natural “stress test” for assumptions about genetic background and ...
Álvaro J. Arana, Laura Sánchez
wiley +1 more source
Outcomes of Pediatric and Adolescent Girls with Malignant Ovarian Germ Cell Tumors after Chemotherapy and Surgery: A Single Institutional Experience. [PDF]
Ali N +7 more
europepmc +1 more source
Epidemiology of Primary Intracranial Neoplasms: A Single-Institute Cross-Sectional Study in Iran. [PDF]
Mortazavi N, Novin K.
europepmc +1 more source
ABSTRACT Dysgerminoma, the most common malignant ovarian germ cell tumor, has a significantly increased incidence in individuals with 46,XY complete gonadal dysgenesis (Swyer syndrome). However, primary amenorrhea is the hallmark presentation of Swyer syndrome in adolescence.
Mahshid Vasef +4 more
wiley +1 more source
ABSTRACT Background Testicular cancer represents the most common solid tumor in young adult males and is associated with excellent long‐term survival outcomes. Aim The aim of this study is to evaluate clinical and pathological characteristics, treatment strategies, and survival outcomes of a large Romanian institutional cohort.
Emanuiela Florentina Rohozneanu +2 more
wiley +1 more source
Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu +6 more
wiley +1 more source
Talin1 is downregulated in testicular germ cell tumors according to combined bioinformatics and experimental approaches. [PDF]
Razmi M +7 more
europepmc +1 more source
Development and functional adaptation of intestinal macrophages across the lifespan
This article discusses intestinal macrophage development, including the influence of developmental origins and life stages; ontogeny and functional heterogeneity; preclinical and clinical evidence. Abstract Macrophages of the gastrointestinal system are central regulators of gut development, homeostasis and disease, yet their origin, functional ...
Baha Mustafa +2 more
wiley +1 more source
Generation and Characterization of Twist1 Acetyl‐Mimic and Acetyl‐Deficient Mouse Models
ABSTRACT TWIST1 encodes a highly conserved basic helix–loop–helix transcription factor essential for embryonic development from Drosophila to humans. TWIST1 activity is regulated by post‐translational modifications, including phosphorylation during development and cancer metastasis. Recent cancer studies identified acetylation of lysines K73 and K76 as
Mary Elmeniawi +6 more
wiley +1 more source

