Results 41 to 50 of about 8,404 (197)

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

Supporting doctors' professional identity development through specialist training

Anatomical Sciences Education, EarlyView.
Abstract Anatomy‐centric specialties such as surgery, radiology, and anatomical pathology (AP) have workforce shortages, with attrition during the training phase proposed as a contributing factor. Current understanding of the reasons behind trainee attrition is limited, and there have been calls to increase the depth and richness of research in this ...
Shemona Y. Rozario, Melanie K. Farlie, Mahbub Sarkar, Michelle D. Lazarus   +3 more
wiley   +1 more source

Supposed pituitary-production of human chorionic Gonadotropin induced by androgen deprivation therapy

International Brazilian Journal of Urology
Introduction: The main cause of slightly elevated human chorionic gonadotropin (HCG) after successful treatment of male germ cell tumors is considered to be pituitary-derived HCG.
Koji Yoshimura, Yoshiharu Nakashima, Kyohei Sugiyama, Naoki Kohei, Akitoshi Takizawa   +4 more
doaj   +1 more source

Central nervous system tumours in children in Ibadan, Nigeria: a histopathologic study

The Pan African Medical Journal, 2016
INTRODUCTION: contrary to some earlier teachings that central nervous system (CNS) tumours are uncommon in black children, these neoplasms are the fourth most common paediatric tumours in Ibadan. Our centre is the major referral centre for CNS tumours in
Gabriel Olabiyi Ogun, Amos Olufemi Adeleye, Olaosebikan Babatunde, Olufunmilola Abimbola Ogun, Ayodeji Salami, Biobele Jotham Brown, Effiong Akang   +6 more
doaj   +1 more source

Umbilical KeyPort bilateral laparoscopic orchiectomy in patient with complete androgen insensitivity syndrome

International Brazilian Journal of Urology, 2012
MAIN FINDINGS: A 22-year-old woman with complete androgen insensitivity syndrome (CAIS) presenting with primary amenorrhea and normal female external genitalia was referred for laparoscopic gonadectomy.
Felipe P. Andrade, Pedro M. Cabrera, Felipe Cáceres, Belen Gil, José M. Rodríguez-Barbero, Javier C. Angulo   +5 more
doaj   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Clinical analysis of 28 cases with pediatric germ cell tumors in pineal region

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To summarize the treatment methods and effects of pediatric germ cell tumors in pineal region. Methods and Results Clinical data of 28 children with primary intracranial pineal region germ cell tumors from March 2012 to December 2019 were ...
Ju⁃lei WANG, Tao HUANG, Qi⁃long TIAN, Jia⁃hua ZHOU, Liang WANG, Yan QU   +5 more
doaj  

Incidence of childhood CNS tumours in Britain and variation in rates by definition of malignant behaviour: population-based study

BMC Cancer, 2019
Background Intracranial and intraspinal tumours are the most numerous solid tumours in children. Some recently defined subtypes are relatively frequent in childhood.
Charles A. Stiller, Anita M. Bayne, Aruna Chakrabarty, Tom Kenny, Paul Chumas   +4 more
doaj   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source