Results 31 to 40 of about 9,124 (231)

Expression of teratocarcinoma-derived growth factor-1 (TDGF-1) in testis germ cell tumors and its effects on growth and differentiation of embryonal carcinoma cell line NTERA2/D1.

, 1997
The teratocarcinoma-derived growth factor-1 (TDGF-1) gene codes for a 188-aminoacid glycoprotein that shares structural homology with the epidermal growth factor (EGF) family of growth factors. TDGF-1 is highly expressed in the undifferentiated embryonal
G. BALDASSARRE, G. SALVATORE, M. G. PERSICO, PEPE, Stefano, I. PAOLETTI, M. RAMBALDI, C. SANDOMENICO, F. ARMENANTE, G. VIGLIETTO, A. ROMANO, G. DE ROSA, S. STAIBANO, Sandomenico C, Persico MG, DE ROSA, GAETANO, Paoletti I, Romano A, Viglietto G., Baldassarre G, Pepe S, Salvatore G, Armenante F, Rambaldi M, STAIBANO, STEFANIA   +23 more
core   +2 more sources

Mature Teratoma Presenting as a Large Nonfunctional Adrenal Lesion: A Case Report and Literature Review

Endocrinology Research and Practice
Primary adrenal teratomas are an exceptionally rare subset of extragonadal germ cell tumors. In this report, we describe a mature adrenal teratoma in a 22-year-old female and provide an updated comprehensive review of adult cases published to date ...
Neslihan Koray Fedai, Emre Hepşen, Ahmet Nihat Koyunlu, Orkun Akman, Ceren Karaçalık Ünver, Sema Hepşen, Erman Çakal   +6 more
doaj   +1 more source

“A tumour registry initiative”

World Neurosurgery: X, 2023
Background: Published literature on epidemiological profile of paediatric brain tumours in India is limited. Aim: To present a retrospective analysis of the histological spectrum of 158 paediatric age group central nervous system tumours operated in a ...
Rajesh Nair, Bhavna Nayal, Saurabh Beedkar, Girish Menon   +3 more
doaj   +1 more source

Signalling events controlling early cell fate decisions in a human embryonal carcinoma cell line, with relation to neural versus non-neural transitions m human ectoderm development [PDF]

, 2007
In this study the human embryonal carcinoma cell line TERA2.cl.spl2 (TERA2.spl2) was utilised as an in vitro model in which to study mechanisms governing neural versus non- neural transitions in the human ectoderm.
Horrocks, Grace Mary
core  

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Treatment of pediatric intracranial germ cell tumors: Tiantan experience

Chinese Journal of Contemporary Neurology and Neurosurgery
Pediatric intracranial germ cell tumors (GCT) are clinically rare but highly heterogeneous tumors, primarily occurring in children and adolescents. The treatment method depends on the tumor type.
LI Xiang, LU Li-juan, GONG Jian
doaj   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Hematopoietic stem cell transplantation for extracranial germ cell tumors

Journal of Bone Marrow Transplantation and Cellular Therapy
Malignant extracranial germ cell tumors (GCT) are uncommon in the pediatric population. Most affected children can achieve cure using conventional chemotherapy combined with appropriate local control.
Neysimelia Costa Villela, Patricia Shimoda Ikeuti, Paulo Henrique dos Santos Klinger, Antonella Zanette, Cláudio Galvão de Castro Junior, Luiz Fernando Lopes   +5 more
doaj   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source