Results 11 to 20 of about 9,124 (231)

Identification of ERβ1 and ERβ2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia [PDF]

Reproductive Biology and Endocrinology, 2009
Background Estrogens exert a role on germ cell physiology of normal human testis through the mediation of the estrogen receptor (ER) beta subtypes. Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-
Rago Vittoria, Romeo Francesco, Giordano Francesca, Ferraro Aurora, Andò Sebastiano, Carpino Amalia   +5 more
doaj   +2 more sources

Gastric teratoma in a 6-month-old boy

African Journal of Paediatric Surgery, 2012
Gastric teratomas are very rare embryonal neoplasms, accounting for 2.6% of all perinatal diagnosed germ cell tumours. About 85% are well-differentiated mature lesions and about 15% are immature tumours with the potential of malignant transformation. The
Peer Wildbrett, Hagen Graf Einsiedel, Björn Lange, Holger Lode, Winfried Barthlen   +4 more
doaj   +2 more sources

Mullerian adenosarcoma-like tumor arising from an extragonadal germ cell tumor: Case Report and Literature Review [PDF]

Human Pathology Reports
Extragonadal germ cell tumors (GCTs) are rare neoplasms, accounting for 1–5 % of all germ cell tumors. Mixed germ cell tumors are neoplasms with more than one GCT component.
Pauline Biesemans, Marcella Baldewijns, Steven Joniau, Tim Van Assche, Marc Claessens, Robert Hente, Wies Vanderbruggen, Wim Volders, Anne-Sophie Van Rompuy   +8 more
doaj   +2 more sources

Diagnosis and management of a rare bilateral ovarian mixed germ cell tumor: a case report [PDF]

Frontiers in Oncology
BackgroundMixed ovarian malignant germ cell tumors (MOGCTs) are rare neoplasms composed of two or more malignant germ cell components, representing less than 1% of all ovarian germ cell tumors.
Xuanling Li, Min You, Xiaoyun Zhang, Jingjing Wei, Guangyao Lin, Qianjue Tang, Lianwei Xu   +6 more
doaj   +2 more sources

Germline Sequencing Identifies Rare Variants in Finnish Subjects with Familial Germ Cell Tumors [PDF]

The Application of Clinical Genetics, 2020
Erin L Crowgey,1 Tea Soini,2 Nidhi Shah,1 Satu-Liisa Pauniaho,2,3 Pekka Lahdenne,2 David B Wilson,4 Markku Heikinheimo,2,4 Todd E Druley4 1Nemours Center for Cancer and Blood Disorders, Nemours Alfred I. duPont Hospital for Children, Wilmington, DE, USA;
Crowgey EL, Soini T, Shah N, Pauniaho SL, Lahdenne P, Wilson DB, Heikinheimo M, Druley TE   +7 more
doaj   +2 more sources

What is new about germ cell ovarian tumors? [PDF]

, 2022
Germ cell tumors of the ovary are the second most frequently found ovarian neoplasms following epithelial ovarian cancers. It is a heterogeneous group with an origin in a primitive germ cells.
Grabska, Kinga; Students’ Scientific Organization of Cancer Cell Biology, Department of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland, Deptała, Andrzej; Department of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland, Fudalej, Marta; Department of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland, Pilarska, Izabela; Students’ Scientific Organization of Cancer Cell Biology, Department of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland, Badowska-Kozakiewicz, Anna; Department of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland, Marta Fudalej, Anna Badowska-Kozakiewicz, Kinga Grabska, Izabela Pilarska, Andrzej Deptała   +9 more
core   +1 more source

Higher LSD1 in Non-Seminomatous Germ Cell Tumors and LSD1 Inhibition by NCL1 Suppresses Embryonal Carcinoma Growth. [PDF]

Cancer Sci
LSD1 expression was higher in non‐seminomatous than in seminomatous testicular germ cell tumor components. In embryonal carcinoma models, selective LSD1 inhibition by NCL1 induced epigenetic and apoptotic responses, reduced viability including in cisplatin‐adapted cells, and suppressed early xenograft outgrowth, supporting LSD1 as a potential ...
Shimizu N, Etani T, Naiki T, Naiki-Ito A, Sugiyama Y, Nagai T, Murakami A, Kato H, Morikawa T, Aoki M, Gonda M, Suzuki H, Tsubouchi Y, Ishikawa D, Suzuki T, Takahashi S, Yasui T.   +16 more
europepmc   +2 more sources

Proton beam therapy in paediatric cancer: Anticipating the opening of the Australian Bragg Centre for Proton Therapy and Research

Journal of Medical Imaging and Radiation Oncology, EarlyView., 2023
Summary Proton Beam Therapy (PBT) has the potential to improve paediatric cancer care by reducing radiation exposure and thus long‐term toxicities. Ethical concerns and debates surrounding the treatment, such as eligibility and accessibility, are ongoing in Australia. The Australian Bragg Centre for Proton Therapy and Research (ABCPTR) (named after Sir
Jeremy Khong, Hui Tee, Peter Gorayski, Hien Le, Michael Penniment, Sophie Jessop, Jordan Hansford, Melanie Penfold, Julia Green, Kelly Skelton, Frank Saran   +10 more
wiley   +1 more source

A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report

Journal of Cardiothoracic Surgery, 2023
Background Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations.
Parviz Mardani, Hooman Kamran, Rezvan Ghaderpanah, Bita Geramizadeh, Damoun Fouladi, Reza Shahriarirad, Armin Amirian   +6 more
doaj   +1 more source

A case series and literature review on 98 pediatric patients of germ cell tumor developing growing teratoma syndrome

Cancer Medicine, 2023
Introduction Malignant germ cell tumors (MGCTs) can develop either extracranially or intracranially. Growing teratoma syndrome (GTS) may develop in these patients following chemotherapy.
Ming‐Yun Hsieh, Hsin‐Hung Chen, Chih‐Ying Lee, Giun‐Yi Hung, Tsung‐Yen Chang, Shih‐Hsiang Chen, Jin‐Yao Lai, Tang‐Her Jaing, Chao‐Neng Cheng, Jiann‐Shiuh Chen, Hsin‐Lin Tsai, Ting‐Yen Yu, Ming‐Hsin Hou, Cheng‐Yin Ho, Hsiu‐Ju Yen   +14 more
doaj   +1 more source