Low-grade glial neoplasms of germ cell origin may represent maturation of embryonic-type neuroectodermal elements. [PDF]
Aims Glial tumours of germ cell origin are relatively rare in men, occurring predominantly after chemotherapy. Many exhibit low‐grade histological features within a spectrum that includes teratomas with mature glial/ganglioglial elements and pure low‐grade tumours with glial/ganglioglial phenotype (LGGT) that ...
Lobo J +10 more
europepmc +3 more sources
A rare case of pure-type embryonal carcinoma in a 75-year-old woman mimicking epithelial ovarian carcinoma [PDF]
Embryonal carcinoma, a very rare ovarian germ cell tumor, involves pure and mixed phenotypes. Pure-type embryonal carcinoma has never been reported in postmenopausal women. The current case was, thus, misdiagnosed as an epithelial ovarian carcinoma based
Hyun Been Jo +7 more
doaj +1 more source
Introduction: sacrococcygeal teratoma (TSC) is the most common tumor of the neonatal period. Alphafetoprotein is an important tumor marker and is used in the follow-up period as a marker of malignancy.
VANESSA DO NASCIMENTO SANTOS +2 more
doaj +2 more sources
Spermatocytic tumor – case report [PDF]
According to the newest WHO classification tumors of the testis are divided into germ cell tumors derived from germ cell neoplasia in situ, germ cell tumors unrelated to germ cell neoplasia in situ, sex cord-stromal tumors, tumors containing both germ ...
Tonći Vodopić +5 more
doaj +1 more source
Primitive neuroectodermal tumors in patients with testicular germ cell tumors usually resemble pediatric-type central nervous system embryonal neoplasms and lack chromosome 22 rearrangements [PDF]
Primitive neuroectodermal tumors (PNETs) are one of the most frequent types of 'non-germ cell' tumor in patients with testicular germ cell tumors and have a guarded prognosis when present in metastatic sites after cisplatin-based chemotherapy. Improved treatments, including targeted therapy, require understanding the biology of these neoplasms.
Thomas M, Ulbright +6 more
openaire +2 more sources
The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior [PDF]
Purpose: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers.
Abbas Basiri +4 more
doaj +1 more source
Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment [PDF]
Primary extragonadal germ-cell tumors (EGCTs) are a rare group of neoplasms, that can exist anywere along the midline of the body, without the evidence of a primary gonadal tumor.
Lucian IORGA +8 more
doaj +1 more source
Rare complication of chemotherapy in testicular cancer [PDF]
Testicular neoplasms metastasizing to the retroperitoneum rarely involve the upper gastrointestinal tract. We describe an unusual case of contained small bowel perforation as a complication of chemotherapy treatment of metastatic non seminomatous germ ...
Goad Abdel Helmy Ehab
doaj +1 more source
Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy [PDF]
PurposeTo evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution.MethodsSixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study ...
Jinsup Kim +7 more
doaj +1 more source
Background Estrogens exert a role on germ cell physiology of normal human testis through the mediation of the estrogen receptor (ER) beta subtypes. Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-
Rago Vittoria +5 more
doaj +1 more source

