The Neoplasia as embryological phenomenon and its implication in the animal evolution and the origin of cancer. I. A presentation of the neoplastic process and its connection with cell fusion and germline formation [PDF]
, 2022 The decisive role of Embryology in understanding the evolution of animal forms is founded and deeply rooted in the history of science. It is recognized that the emergence of multicellularity would not have been possible without the formation of the first embryo.
arxiv +1 more source
Detection of bovine papillomavirus type 2 in the peripheral blood of cattle with urinary bladder tumours: possible biological role [PDF]
, 2008 Bovine papillomavirus type 2 (BPV-2) infection has been associated with urinary bladder tumours in adult cattle grazing on bracken fern-infested land. In this study, we investigated the simultaneous presence of BPV-2 in whole blood and urinary bladder ...
A. Venuti +10 more
core +1 more source
The rotational and divergent components of atmospheric circulation on tidally locked planets [PDF]
Proc. Nat. Acad. Sci., 118 (13), e2022705118 (2021), 2021 Tidally locked exoplanets likely host global atmospheric circulations with a superrotating equatorial jet, planetary-scale stationary waves and thermally-driven overturning circulation. In this work, we show that each of these features can be separated from the total circulation by using a Helmholtz decomposition, which splits the circulation into ...
arxiv +1 more source
The role of ras gene in the development of haemic neoplasia in Mytilus trossulus [PDF]
, 2006 Disseminated neoplasia has been reported in mussels (Mytilus spp) from numerous locations worldwide. This condition is progressive and fatal and the aetiology is unknown.
Barber +9 more
core +2 more sources
Neoplastic circulating endothelial cells in multiple myeloma with 13q14 deletion
Blood, 2006 Abstract In multiple myeloma (MM), circulating endothelial cells (CECs) represent a vascular marker of angiogenesis and may reflect tumor mass. In this report, we showed that, in 5 MM patients with 13q14 deletion, CECs carried the same chromosome aberration as the neoplastic plasma cells (11%-32% of CECs with 13q14 deletion). Most of the
RIGOLIN, Gian Matteo +8 more
openaire +5 more sources
Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells [PDF]
, 2012 DNA methylation might be the earliest somatic genome changes in prostate cancer that also play an important role in the process of tumor invasion, growth and metastasis.
D'Alessandro, Anna Maria +9 more
core +1 more source
What information could the main actors of liquid biopsy provide? A representative case of non-small cell lung cancer (NSCLC) [PDF]
, 2018 In non-small cell lung cancer (NSCLC), there is a consensus regarding the use of liquid biopsy, generally, to detect "druggable" mutations and, in particular, to monitor tyrosine kinase inhibitor (TKI) treatments. However, whether circulating tumor cells
Manicone, M. +6 more
core +1 more source
Forward Modeling Helioseismic Signatures of One- and Two-cell Meridional Circulation [PDF]
ApJ, 911, 90 (2021), 2021 Using a 3D global solver of the linearized Euler equations, we model acoustic oscillations over background velocity flow fields of single-cell meridional circulation with deep and shallow return flows as well as double-cell meridional circulation with strong and weak reversals.
arxiv +1 more source
Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms. [PDF]
, 2018 Many patients with B-cell malignancies can be successfully treated, although tumor eradication is rarely achieved. T-cell-directed killing of tumor cells using engineered T-cells or bispecific antibodies is a promising approach for the treatment of ...
Aliberti S +24 more
core +1 more source
Blood and skin-derived Sezary cells: differences in proliferation-index, activation of PI3K/AKT/mTORC1 pathway and its prognostic relevance [PDF]
, 2019 Sézary syndrome (SS) is a rare and aggressive variant of Cutaneous T-Cell Lymphoma characterized by neoplastic distribution mainly involving blood, skin, and lymph-node.
Benucci, Roberto +15 more
core +1 more source