Results 21 to 30 of about 206,954 (242)

Neoplastic circulating endothelial cells in multiple myeloma with 13q14 deletion

Blood, 2006
Abstract In multiple myeloma (MM), circulating endothelial cells (CECs) represent a vascular marker of angiogenesis and may reflect tumor mass. In this report, we showed that, in 5 MM patients with 13q14 deletion, CECs carried the same chromosome aberration as the neoplastic plasma cells (11%-32% of CECs with 13q14 deletion). Most of the
RIGOLIN, Gian Matteo, FRAULINI, Chiara, CICCONE, Maria, MAURO, Endri, BUGLI, Anna Maria, DE ANGELI, Cristiano, NEGRINI, Massimo, CUNEO, Antonio, CASTOLDI, Gianluigi   +8 more
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Sensitivity of canine hematological cancers to BH3 mimetics

Journal of Veterinary Internal Medicine, 2023
Background Inhibition of antiapoptotic B‐cell lymphoma 2 (BCL2) proteins by small molecule Bcl‐2 homology 3 (BH3) mimetics causes rapid induction of apoptosis of human hematological cancers in vitro and in vivo.
Selvi Jegatheeson, Claire Cannon, Caroline Mansfield, Joanne Devlin, Andrew Roberts   +4 more
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Pivotal Role of Pervasive Neoplastic and Stromal Cells Reprogramming in Circulating Tumor Cells Dissemination and Metastatic Colonization [PDF]

Cancer Microenvironment, 2014
Reciprocal interactions between neoplastic cells and their microenvironment are crucial events in carcinogenesis and tumor progression. Pervasive stromal reprogramming and remodeling that transform a normal to a tumorigenic microenvironment modify numerous stromal cells functions, status redox, oxidative stress, pH, ECM stiffness and energy metabolism.
Didier, Meseure, Kinan, Drak Alsibai, Andre, Nicolas   +2 more
openaire   +2 more sources

Less micrometastatic risk related to circulating tumor cells after endoscopic breast cancer surgery compared to open surgery

BMC Cancer, 2019
Background Increase of circulating tumor cells (CTCs) has been found after surgery for various carcinomas but not confirmed for breast cancer, and whether endoscopic surgery confers identical effect to CTCs as open surgery did is not clear.
Shichao Li, Wenting Yan, Xinhua Yang, Li Chen, Linjun Fan, Haoxi Liu, Kun Liu, Yi Zhang, Jun Jiang   +8 more
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From Bench to Bedside in Tongue Muscle Cancer Invasion and Back again: Gross Anatomy, Microanatomy, Surgical Treatments and Basic Research

Life, 2020
Tongue squamous cell carcinoma is the most common malignancy in the oral cavity. Despite advances in diagnosis and treatment, the prognosis of advanced states has not significantly improved.
Luca Calabrese, Maria Eleonora Bizzoca, Roberto Grigolato, Fausto Antonio Maffini, Marta Tagliabue, Rosa Negro, Stefania Leuci, Michele Davide Mignogna, Lorenzo Lo Muzio   +8 more
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Prognostic Value of Multiple Reverse Transcription-PCR Tyrosinase Testing for Circulating Neoplastic Cells in Malignant Melanoma [PDF]

Clinical Chemistry, 2003
Abstract Background: The reverse transcription-PCR tyrosinase assay (TYR test) cannot reliably detect malignant melanoma (MM) cells in blood as the cells often circulate at low concentrations. We evaluated the prognostic value of multiple TYR testing, the prognostic significance of individual positive TYR test results (TYR+) in ...
Jolanta, Szenajch, Bogdan, Jasiński, Agnieszka, Synowiec, Jadwiga, Kulik, Małgorzata, Chomicka, Jerzy, Struzyna, Zbigniew, Nowecki, Piotr, Rutkowski, Włodzimierz, Ruka, Witold, Kupść, Janusz A, Siedlecki, Wiesław, Wiktor-Jedrzejczak   +11 more
openaire   +2 more sources

Reduction of T Lymphoma Cells and Immunological Invigoration in a Patient Concurrently Affected by Melanoma and Sezary Syndrome Treated With Nivolumab

Frontiers in Immunology, 2020
Despite the recent availability of several new drugs in hemato-oncology, T-cell lymphomas are still incurable and PD-1 blockade could represent a therapeutic chance for selected patients affected by these malignancies, although further studies are ...
Maria Grazia Narducci, Anna Tosi, Alessandra Frezzolini, Enrico Scala, Francesca Passarelli, Laura Bonmassar, Alessandro Monopoli, Maria Pina Accetturi, Maria Cantonetti, Gian Carlo Antonini Cappellini, Federica De Galitiis, Antonio Rosato, Antonio Rosato, Mario Picozza, Giandomenico Russo, Stefania D’Atri   +15 more
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Unique Immune Gene Expression Patterns in Bronchoalveolar Lavage and Tumor Adjacent Non-Neoplastic Lung Tissue in Non-Small Cell Lung Cancer

Frontiers in Immunology, 2018
BackgroundThe immune cells in the local environments surrounding non-small cell lung cancer (NSCLC) implicate the balance of pro- and antitumor immunity; however, their transcriptomic profiles remain poorly understood.MethodsA transcriptomic microarray ...
Chih-Hsi Scott Kuo, Chih-Hsi Scott Kuo, Chien-Ying Liu, Stelios Pavlidis, Yu-Lun Lo, Yen-Wen Wang, Chih-Hung Chen, How-Wen Ko, Fu-Tsai Chung, Tin-Yu Lin, Tsai-Yu Wang, Kang-Yun Lee, Yi-Ke Guo, Tzu-Hao Wang, Cheng-Ta Yang   +14 more
doaj   +1 more source

Tumor-Infiltrating Macrophages in Post-Transplant, Relapsed Classical Hodgkin Lymphoma Are Donor-Derived. [PDF]

PLoS ONE, 2016
Tumor-associated inflammatory cells in classical Hodgkin lymphoma (CHL) typically outnumber the neoplastic Hodgkin/Reed-Sternberg (H/RS) cells. The composition of the inflammatory infiltrate, particularly the fraction of macrophages, has been associated ...
Genevieve M Crane, Mark A Samols, Laura A Morsberger, Raluca Yonescu, Michele L Thiess, Denise A S Batista, Yi Ning, Kathleen H Burns, Milena Vuica-Ross, Michael J Borowitz, Christopher D Gocke, Richard F Ambinder, Amy S Duffield   +12 more
doaj   +1 more source

Circulating Tumor Cell Number Is Associated with Primary Tumor Volume in Patients with Lung Adenocarcinoma

Tuberculosis and Respiratory Diseases, 2020
Background Circulating tumor cells (CTCs) are frequently detected in patients with advanced-stage malignant tumors and could act as a predictor of poor prognosis.
Byung Ju Kang, M.D., Ph.D., Seung Won Ra, M.D., Ph.D.,, Kyusang Lee, Ph.D., Soyeoun Lim, M.D., M.S., So Hee Son, M.S., Jong-Joon Ahn, M.D., Ph.D., Byung Chul Kim, Ph.D.   +6 more
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