Results 51 to 60 of about 432,951 (336)

Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate [PDF]

Oncotarget, 2017
Mesenchymal Stem Cells (MSCs) have been identified in prostate cancer, raising the critical question of their physical and temporal source. Therefore, MSCs were quantified and characterized in benign and malignant prostate tissue representing different disease states and a wide range of age groups from fetal development through adult death using ...
Brennen, W Nathaniel, Zhang, Baohui, Kulac, Ibrahim, Kisteman, L Nelleke, Antony, Lizamma, Wang, Hao, Meeker, Alan K, De Marzo, Angelo M, Garraway, Isla P, Denmeade, Samuel R, Isaacs, John T   +10 more
openaire   +4 more sources

A Murine Model With JAK2V617F Expression in Both Hematopoietic Cells and Vascular Endothelial Cells Recapitulates the Key Features of Human Myeloproliferative Neoplasm

Frontiers in Oncology, 2021
The myeloproliferative neoplasms (MPNs) are characterized by an expansion of the neoplastic hematopoietic stem/progenitor cells (HSPC) and an increased risk of cardiovascular complications.
Haotian Zhang, Amar Yeware, Sandy Lee, Huichun Zhan, Huichun Zhan   +4 more
doaj   +1 more source

Cytoplasmic expression of LGR5 in pancreatic adenocarcinoma.

Frontiers in Physiology, 2013
Background: CD133 has been identified as a cancer stem cell (CSC) marker for pancreatic ductal adenocarcinoma. Although leucine-rich-repeat-containing G-protein-coupled receptor 5 (LGR5), a marker of intestinal stem cells, has been shown to be on a ...
Nobumasa eMizuno, Yasushi eYatabe, Kazuo eHara, Susumu eHijioka, Hiroshi eImaoka, Yasuhiro eShimizu, Shigeru B.H. Ko, Kenji eYamao   +7 more
doaj   +1 more source

Prolactin and its receptor as therapeutic targets in glioblastoma multiforme [PDF]

, 2019
Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore their contribution in GBM pathogenesis.
Abt, Araceli, Asad, Antonela Sofía, Boutillon, Florence, Candolfi, Marianela, de Simone, Emilio Adrian, Ferraris, Maria Jimena, Goffin, Vincent, González, Nazareno, Nicola Candia, Alejandro Javier, Orrillo, Santiago Jordi, Pisera, Daniel Alberto, Seilicovich, Adriana, Yael, Lastra, Zuccato, Camila Florencia   +13 more
core   +1 more source

Complexity of the Genetic Background of Oncogenesis in Ovarian Cancer—Genetic Instability and Clinical Implications

Cells
Ovarian cancer is a leading cause of death among women with gynecological cancers, and is often diagnosed at advanced stages, leading to poor outcomes.
Marek Murawski, Adam Jagodziński, Aleksandra Bielawska-Pohl, Aleksandra Klimczak   +3 more
doaj   +1 more source

Stromal CD10 expression in breast cancer correlates with tumor invasion and cancer stem cell phenotype

BMC Cancer, 2018
Background Previous investigations have indicated that CD10 is associated with biological aggressivity in human cancers, but the use of this marker for diagnosis and prognosis is more complex.
Tahani Louhichi, Hanene Saad, Myriam Ben Dhiab, Sonia Ziadi, Mounir Trimeche   +4 more
doaj   +1 more source

A preclinical model for the ATLL lymphoma subtype with insights into the role of microenvironment in HTLV-1-mediated lymphomagenesis [PDF]

, 2018
\uef7f View references (83) Adult T cell Leukemia/Lymphoma (ATLL) is a mature T cell malignancy associated with Human T cell Leukemia Virus type 1 (HTLV-1) infection.
Adriana Mattiolo, Alberto Amadori, Alberto Amadori, Barbara Montini, Ilaria Cavallari, Luigi Chieco-Bianchi, Maria Assunta Piano, Maria Luisa Calabrò, Mattia Vicario   +8 more
core   +2 more sources

Adult human mesenchymal stem cell as a target for neoplastic transformation [PDF]

Oncogene, 2004
The neoplastic process may involve a cancer stem cell. This concept has emerged largely from the careful analysis of tumour biopsy systems from haematological, breast and brain tumours. However, the experimental systems necessary to provide the cellular and molecular evidence to support this important concept have been lacking.
Serakinci N, Guldberg P, Burns JS, Abdallah B, Schrodder H, Jensen T, Kassem M   +6 more
openaire   +4 more sources

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Transformed bone marrow cells generate neoplasms of distinct histogenesis. a murine model of cancer transplantation

Stem Cell Research, 2019
The last several years have witnessed renewed interest regarding the contribution of cancer stem cells in tumorigenesis and neoplastic heterogeneity. It has been reported that patients who undergo bone marrow transplantation are more prone to develop a ...
Mireia Castillo-Martin, Nataliya Gladoun, Dan Han, Adolfo Firpo-Betancourt, Jose M. Silva, Carlos Cordon-Cardo   +5 more
doaj   +1 more source