Results 131 to 140 of about 314,513 (244)

Tumor necrosis factor promotes doublecortin-like kinase 1 expression and cellular reprogramming in intestinal epithelial cells leading to neoplastic transformation. [PDF]

Cell Commun Signal
Huang L, Li T, Huang X, Chen X, Ju Y, Xu L, Ma C, Tao Y, Yang Y, Bian X, Huycke MM, Wang X.   +11 more
europepmc   +1 more source

Hemangioblastomas might derive from neoplastic transformation of neural stem cells/progenitors in the specific niche [PDF]

, 2010
Dexuan Ma, Mingchang Zhang, Liang Chen, Qisheng Tang, Xu Tang, Ying Mao, Liangfu Zhou   +6 more
openalex   +1 more source

Data from Polycomb Group Protein Enhancer of Zeste 2 Is an Oncogene That Promotes the Neoplastic Transformation of a Benign Prostatic Epithelial Cell Line

, 2023
Breanne D.W. Karanikolas, Marxa L. Figueiredo, Lily Wu   +2 more
openalex   +1 more source

Imaging Flow Cytometry Detection of Cytogenetic Abnormalities in Circulating CD34+ Cells Predicts Leukemic Transformation in Myelofibrosis

Cytometry Part A, EarlyView.
ABSTRACT Myelofibrosis is a myeloproliferative neoplasm with potential to transform to acute myeloid leukemia. This evolution is unpredictable and current assays lack the sensitivity and applicability needed to predict this transformation. While population‐level data utilizing comprehensive genomic profiling can identify subgroups at higher risk of ...
Ruby M. Hamilton, Ryan J. Collinson, Henry Y. Hui, Zi Yun Ng, Hun S. Chuah, Malcolm Webb, Belinda B. Guo, Wendy N. Erber, Kathy A. Fuller   +8 more
wiley   +1 more source

The endonuclease activity of MCPIP1 controls the neoplastic transformation of epithelial cells via the c-Met/CD44 axis. [PDF]

Cell Commun Signal
Marona P, Myrczek R, Piasecka I, Gorka J, Kwapisz O, Pospiech E, Rys J, Jura J, Miekus K.   +8 more
europepmc   +1 more source

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

Developmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara   +9 more
wiley   +1 more source

Endoscopic and pathological features of neoplastic transformation of gastric hyperplastic polyps: Retrospective study of 4010 cases. [PDF]

World J Gastrointest Oncol
Zhang DX, Niu ZY, Wang Y, Zu M, Wu YH, Shi YY, Zhang HJ, Zhang J, Ding SG.   +8 more
europepmc   +1 more source

Inhibitors of endogenous nitrogen oxide formation block the promotion of neoplastic transformation in C3H 10T1/2 fibroblasts [PDF]

, 1993
Lawrence J. Mordan, Terrilea Burnett, Lixin Zhang, Jaimie Tom, Robert V. Cooney   +4 more
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

miR-1297 is frequently downmodulated in flat epithelial atypia of the breast and promotes mammary neoplastic transformation via EphrinA2 regulation. [PDF]

J Exp Clin Cancer Res
Scafetta G, Rampioni Vinciguerra GL, Giglio S, Faruq O, Cirombella R, Segatto I, Citron F, Mattevi MC, Di Renzi E, Cascione L, Gasparini P, Belletti B, Baldassarre G, Sacconi A, Blandino G, Vecchione A.   +15 more
europepmc   +1 more source