Results 181 to 190 of about 331,839 (297)

Identification of tumor initiating cells and early marker genes in histologically normal colonic mucosa that lead to neoplastic transformation. [PDF]

Neoplasia
Jaiswal S, The S, Chang TS, Shi J, Wang TD.   +4 more
europepmc   +1 more source

E.: Neoplastic transformation of mouse and hamster cells in vitro with and without polyoma virus

, 1967
SUMMARY-Several cell lines were examined under different culture conditions in an effort to find one that would not undergo "spontaneous" neoplastic transformation but could be transformed by polyoma virus.
Katherine K. Sanford, Robert E. Hoemann, Sanford, K K, Hoemann, R E   +3 more
core  

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

A Modified Arthroscopic Trans‐Septal Approach via the Figure‐to‐4 Position of the Knee

Arthroscopy Techniques, EarlyView.
Abstract Standard anterior and posterior portals offer limited access to pathologies in the posterior compartment of the knee. The trans‐septal portal facilitates comprehensive visualization and instrumentation in the posterolateral and posteromedial compartments.
Ning Sheng, Li Sun, Junrong Chen, Qiuyue Ding, Zhihui Yan   +4 more
wiley   +1 more source

METTL3-dependent m6A RNA methylation suppresses aberrant mammary epithelial differentiation and neoplastic transformation. [PDF]

Proc Natl Acad Sci U S A
Li Y, Qiu X, Sandusky Z, Tagliaferri K, Li R, Yang X, Zhang T, Liu S, Yan P, Lu F, Jones M, Xiao T, Li W, Goldman S, Cui J, Polyak K, Liu XS, Long HW, Gregory RI, Adelman K, Rosenbluth JM, Brown M.   +21 more
europepmc   +1 more source

Osteopontin mRNA expression by rat mesothelial cells exposed to multi-walled carbon nanotubes as a potential biomarker of chronic neoplastic transformation in vitro. [PDF]

Toxicol In Vitro, 2021
Sridharan S, Taylor-Just A, Bonner JC.
europepmc   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Endo180 and basement membrane stiffness induce OXPHOS and neoplastic transformation in aging prostate epithelia. [PDF]

NPJ Aging
Pastro L, Martínez J, Fontenla S, Chiale AC, Faulord A, Frade MP, Díaz AS, Martino-Kunsch R, Castro L, Schenk L, Quijano C, Sturge J, Rodríguez-Teja M.   +12 more
europepmc   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Tumor necrosis factor promotes doublecortin-like kinase 1 expression and cellular reprogramming in intestinal epithelial cells leading to neoplastic transformation. [PDF]

Cell Commun Signal
Huang L, Li T, Huang X, Chen X, Ju Y, Xu L, Ma C, Tao Y, Yang Y, Bian X, Huycke MM, Wang X.   +11 more
europepmc   +1 more source