Food Safety and Health, EarlyView.In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
The endonuclease activity of MCPIP1 controls the neoplastic transformation of epithelial cells via the c-Met/CD44 axis. [PDF]
Cell Commun SignalMarona P +8 more
europepmc +1 more source
Null Effects of the State Pension Age on Mortality in the Netherlands
Health Economics, EarlyView.ABSTRACT Increasing the state pension (SP) age in the Netherlands from 65 years in 2012 to 67 in 2024 has been shown to cause individuals to work longer. This study addresses a concern regarding possible adverse health effects of an increased SP‐age, for example, because individuals trade health investments for working time. We empirically investigated
Adriaan Kalwij, Arie Kapteyn
wiley +1 more source
Carcinogenic Mechanisms of Hexavalent Chromium: From DNA Breaks to Chromosome Instability and Neoplastic Transformation. [PDF]
Curr Environ Health RepMeaza I +4 more
europepmc +1 more source
Head &Neck, EarlyView.ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell +11 more
wiley +1 more source
miR-1297 is frequently downmodulated in flat epithelial atypia of the breast and promotes mammary neoplastic transformation via EphrinA2 regulation. [PDF]
J Exp Clin Cancer ResScafetta G +15 more
europepmc +1 more source
The Utility of Nucleolar Organizer Regions Quantitation in Early Prediction of Lung Neoplastic Transformation. [PDF]
Cureus, 2020 Ahmed HG +7 more
europepmc +1 more source
Head &Neck, EarlyView.ABSTRACT Background Frailty and sarcopenia may influence head and neck cancer (HNC) treatment outcomes, including dysphagia. Current understanding of this relationship, however, remains limited. This scoping review aimed to synthesize existing evidence on the relationship between frailty and/or sarcopenia and dysphagia in adults with HNC.
Rishni Perera +4 more
wiley +1 more source
Head &Neck, EarlyView.ABSTRACT Background Fanconi anemia (FA) is associated with markedly increased risk for early‐onset oral squamous cell carcinoma (OSCC). Methods We report an aggressive mandibular squamous cell carcinoma in a 26‐year‐old non‐transplanted woman with FA initially interpreted as localized periodontal disease adjacent to a tongue leukoplakia.
Cassius Carvalho Torres‐Pereira +4 more
wiley +1 more source
The <i>plk1</i> Gene Regulatory Network Modeling Identifies Three Circuits for <i>plk1</i>-mediated Genomic Instability Leading to Neoplastic Transformation. [PDF]
Life (Basel)Suescum-Holguín JF +3 more
europepmc +1 more source