Results 191 to 200 of about 383,457 (302)

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Endoscopic and pathological features of neoplastic transformation of gastric hyperplastic polyps: Retrospective study of 4010 cases. [PDF]

World J Gastrointest Oncol
Zhang DX, Niu ZY, Wang Y, Zu M, Wu YH, Shi YY, Zhang HJ, Zhang J, Ding SG.   +8 more
europepmc   +1 more source

Endoscopic Resection of Bizarre Parosteal Osteochondromatous Proliferation of the Calcaneocuboid Joint

Arthroscopy Techniques, EarlyView.
Abstract Bizarre parosteal osteochondromatous proliferation (BPOP), or Nora's lesion, is an unusual, benign, parosteal lesion comprising bone, fibrous tissue, and cartilage. Clinically, the lesions present as slowly growing hard protuberances that are painless in most cases unless they cause local symptoms due to mass effect, including pain, palpable ...
Tun Hing Lui, Kit Leung
wiley   +1 more source

miR-1297 is frequently downmodulated in flat epithelial atypia of the breast and promotes mammary neoplastic transformation via EphrinA2 regulation. [PDF]

J Exp Clin Cancer Res
Scafetta G, Rampioni Vinciguerra GL, Giglio S, Faruq O, Cirombella R, Segatto I, Citron F, Mattevi MC, Di Renzi E, Cascione L, Gasparini P, Belletti B, Baldassarre G, Sacconi A, Blandino G, Vecchione A.   +15 more
europepmc   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Carcinogenic Mechanisms of Hexavalent Chromium: From DNA Breaks to Chromosome Instability and Neoplastic Transformation. [PDF]

Curr Environ Health Rep
Meaza I, Williams AR, Wise SS, Lu H, Wise JP.   +4 more
europepmc   +1 more source

The Utility of Nucleolar Organizer Regions Quantitation in Early Prediction of Lung Neoplastic Transformation. [PDF]

Cureus, 2020
Ahmed HG, El Hag AB, Binsaleh NK, Elhussein GEMO, Hussain MA, Bealy MABI, Abboh EAA, Sherfi H.   +7 more
europepmc   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

The <i>plk1</i> Gene Regulatory Network Modeling Identifies Three Circuits for <i>plk1</i>-mediated Genomic Instability Leading to Neoplastic Transformation. [PDF]

Life (Basel)
Suescum-Holguín JF, Clavijo-Buriticá DC, Carrillo-Borda EF, Quimbaya MA.   +3 more
europepmc   +1 more source

Multifaceted Roles of DNA Methylation in Neoplastic Transformation, from Tumor Suppressors to EMT and Metastasis. [PDF]

Genes (Basel), 2020
Casalino L, Verde P.
europepmc   +1 more source