Results 211 to 220 of about 314,513 (244)
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ONCOGENES: THEIR ROLE IN NEOPLASTIC TRANSFORMATION
Annual Review of Microbiology, 1985Revue centree sur les oncogenes myc, myb, fes/fps et sis, avec insistance sur l'analyse structurale de ces genes dans les cellules humaines en comparaison de leurs homologues viraux, leur localisation chromosomique en rapport avec les translocations specifiques dans les affections malignes, les mecanismes et types d'activation transcriptionnelle et ...
L, Ratner, S F, Josephs, F, Wong-Staal
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Organoids as Models for Neoplastic Transformation
Annual Review of Pathology: Mechanisms of Disease, 2016Cancer models strive to recapitulate the incredible diversity inherent in human tumors. A key challenge in accurate tumor modeling lies in capturing the panoply of homo- and heterotypic cellular interactions within the context of a three-dimensional tissue microenvironment.
James T, Neal, Calvin J, Kuo
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Mechanisms of neoplastic transformation.
Cancer investigation, 1984This paper introduces a series of invited essays on current controversies in basic cancer research. The initial group of essays focuses on the detection and interpretation of molecular and cellular changes suspected to be of importance in the cause and pathogenesis of cancer. There are two formats: (i) differing viewpoints are presented in parallel, or
R J, Monnat, L A, Loeb
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GAP junctions during neoplastic transformation
2000Publisher Summary This chapter focuses on the gap junctions during neoplastic transformation. It examines the role of gap junctional communication during normal cell proliferation, describes the cellular machinery that controls gap junctional communication, and describes the many mechanisms that can modify gap junctional communication during ...
Mark J. Neveu, John Bertram
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Angiogenesis and Neoplastic Transformation
1992The major symptom of the neoplastic diseases is the unrestrained growth of cell populations with formation in most cases of solid tumors. Passage of cells into circulation and metastases formation completes the lethal outcome of the disease. When an agglomerate of cells is being formed in vivo, the increment in volume is conditioned by the supply ...
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Neoplastic transformation arising in Peutz-Jeghers polyposis
Diseases of the Colon & Rectum, 1993To clarify the potential for malignancy of Peutz-Jeghers polyposis, we investigated 75 gastrointestinal polyps resected surgically or endoscopically from seven patients with this syndrome.There were 19 polyps in the stomach, 18 in the duodenum, 22 in the small intestine, and 16 in the large intestine, and these were histologically composed of 1 ...
K, Hizawa +5 more
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Glycosaminoglycans and neoplastic transformation.
Anticancer research, 1983Two classes of mammalian glycosaminoglycans (GAGs) are distinguished: hyaluronic acid and chondroitin sulphate homopolymers, exhibiting identical repetitive building blocks, versus heparan and dermatan sulphate co-polymers, with differently substituted disaccharidic units.
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Cell Surfaces in Neoplastic Transformation
1971Publisher Summary This chapter describes the properties, and the chemical and physiological aspects of cell surfaces in neoplastic transformation. Immunological surface disparities between normal and tumor cells have been studied for decades, while attempts to bring them into the realm of biochemistry have been extremely rare.
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Neoplastic transformation in vitro.
Polish journal of pharmacology and pharmacy, 1980Oncogenic transformation of cultured cells is considered to be analogous to the induction of tumors in animals. Two properties of transformed cells: the capacity to grow in soft agar and morphological alterations were used as a basis for quantitative studies on the transforming properties of chemicals.
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Sex Hormones and Neoplastic Transformation
1996Hormones have pervasive effects on cellular processes, since they can regulate cell growth and differentiation, metabolic activity, and the metabolism of both endogenous and exogenous substances. Moreover, hormones can affect neoplastic processes by acting either as the sole etiologic agent or in conjunction with nonhormonal chemical carcinogens or ...
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