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Proceedings of the Conference on Transformation Groups
Conference on Transformation Groups
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[Chromosomal translocation and neoplastic transformation].
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Neoplastic Transformation Induced by Carbon Ions
International Journal of Radiation Oncology Biology Physics, 2009The objective of this experiment was to compare the oncogenic potential of carbon ion beams and conventional photon beams for use in radiotherapy.The HeLa X human skin fibroblast cell line CGL1 was irradiated with carbon ions of three different energies (270, 100, and 11.4 MeV/u). Inactivation and transformation data were compared with those for 15 MeV
Claudio Giustino Stucchi
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ONCOGENES: THEIR ROLE IN NEOPLASTIC TRANSFORMATION
Annual Review of Microbiology, 1985Revue centree sur les oncogenes myc, myb, fes/fps et sis, avec insistance sur l'analyse structurale de ces genes dans les cellules humaines en comparaison de leurs homologues viraux, leur localisation chromosomique en rapport avec les translocations specifiques dans les affections malignes, les mecanismes et types d'activation transcriptionnelle et ...
L, Ratner, S F, Josephs, F, Wong-Staal
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Organoids as Models for Neoplastic Transformation
Annual Review of Pathology: Mechanisms of Disease, 2016Cancer models strive to recapitulate the incredible diversity inherent in human tumors. A key challenge in accurate tumor modeling lies in capturing the panoply of homo- and heterotypic cellular interactions within the context of a three-dimensional tissue microenvironment.
James T, Neal, Calvin J, Kuo
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Lipoprotein(a) in neoplastic transformation
Clinica Chimica ActaCardiovascular diseases and cancer are top global causes of death, sharing risk factors and treatment strategies. Although dyslipidemia is linked to both, its exact roles are unclear. Recent studies suggest a potential association between plasma lipoprotein(a) levels and cancer risk.
Dan-Qi, Han +5 more
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The mechanisms of neoplastic transformation
European Journal of Cancer, 2001Historically, the contemporary understanding of tumours developed hand in hand with Virchow’s notion that the cell was the basic element of many diseases. Indeed, classical pathology began early on to describe a multitude of cancers, but, at the same time, it was also quick to recognise features that were common to them all, and this led to the concept
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The cytology of spontaneous neoplastic transformation in culture
In Vitro, 1977Thirteen cell lines derived from embryos of the mouse, rat and hamster were sampled at closely spaced intervals for cytology and spontaneous neoplastic transformation. Transformation, determined by growth of the cells as malignant neoplasms in compatible hosts, occurred in eight lines and appeared to be unrelated to time in culture, passage number ...
S L, Handleman +3 more
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Pulsed ultrasound and neoplastic transformation in vitro
Ultrasound in Medicine & Biology, 1991C3H/10T1/2 mouse embryo fibroblast cells grown as 1.2 cm diameter monolayers were assayed for cytotoxicity and neoplastic transformation following 30 min insonations with three types of pulsed ultrasound (US). Two of the US beams, with a repetition frequency of 1 kHz, center frequencies of 2.5 and 3.5 MHz and time-averaged intensities (ITA) of 31 and 6.
G H, Harrison, E K, Balcer-Kubiczek
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The Neoplastic Transformation of SCID Cells by Radiation
Radiation Research, 1999Severe combined immunodeficiency (SCID) cells are hypersensitive to killing by ionizing radiation because of deregulation of DNA-dependent protein kinase (DNA-PK) and a concomitant deficiency in the repair of DNA double-strand breaks. The effect of this condition on the neoplastic transformation of SCID fibroblasts, designated SCID 3T1, has been ...
M, Lun +4 more
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