Results 241 to 250 of about 1,988,958 (283)
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Neoplastic Cell Transformation by Heavy Ions
Radiation Research, 1989We have studied the induction of morphological transformation by heavy ions. Golden hamster embryo cells were irradiated with 95 MeV 14N ions (530 keV/microns), 22 MeV 4He ions (36 keV/microns), and 22 MeV 4He ions with a 100-microns Al absorber (77 keV/microns) which were generated by a cyclotron at the Institute of Physical and Chemical Research in ...
M, Suzuki +4 more
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Angiogenesis and Neoplastic Transformation
1992The major symptom of the neoplastic diseases is the unrestrained growth of cell populations with formation in most cases of solid tumors. Passage of cells into circulation and metastases formation completes the lethal outcome of the disease. When an agglomerate of cells is being formed in vivo, the increment in volume is conditioned by the supply ...
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Mechanisms of neoplastic transformation.
Cancer investigation, 1984This paper introduces a series of invited essays on current controversies in basic cancer research. The initial group of essays focuses on the detection and interpretation of molecular and cellular changes suspected to be of importance in the cause and pathogenesis of cancer. There are two formats: (i) differing viewpoints are presented in parallel, or
R J, Monnat, L A, Loeb
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The role of selection in progressive neoplastic transformation
2001Mathematical modeling indicates that selective growth of cells with biallelic mutations in tumor suppressor genes is the driving force in the development of most human tumors, and that increased mutation rate is not required. Spontaneous neoplastic transformation of cells in culture offers the opportunity for quantitative analysis of all stages of ...
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Glycosaminoglycans and neoplastic transformation.
Anticancer research, 1983Two classes of mammalian glycosaminoglycans (GAGs) are distinguished: hyaluronic acid and chondroitin sulphate homopolymers, exhibiting identical repetitive building blocks, versus heparan and dermatan sulphate co-polymers, with differently substituted disaccharidic units.
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Neoplastic transformation in vitro.
Polish journal of pharmacology and pharmacy, 1980Oncogenic transformation of cultured cells is considered to be analogous to the induction of tumors in animals. Two properties of transformed cells: the capacity to grow in soft agar and morphological alterations were used as a basis for quantitative studies on the transforming properties of chemicals.
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Mutation and Neoplastic Transformation
Annals of the New York Academy of Sciences, 1988J C, Barrett +3 more
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Sex Hormones and Neoplastic Transformation
1996Hormones have pervasive effects on cellular processes, since they can regulate cell growth and differentiation, metabolic activity, and the metabolism of both endogenous and exogenous substances. Moreover, hormones can affect neoplastic processes by acting either as the sole etiologic agent or in conjunction with nonhormonal chemical carcinogens or ...
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Cell Surfaces in Neoplastic Transformation
1971Publisher Summary This chapter describes the properties, and the chemical and physiological aspects of cell surfaces in neoplastic transformation. Immunological surface disparities between normal and tumor cells have been studied for decades, while attempts to bring them into the realm of biochemistry have been extremely rare.
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Tyrosine kinase activities and neoplastic transformation
Biochemical Society Transactions, 1990Felice, G, Horvath, AR, Kellie, S
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