Results 51 to 60 of about 8,276 (115)
Abstract INTRODUCTION Biomarkers (BMs) are valuable tools to facilitate early diagnosis of (subtypes of) diseases, improve patient selection and stratification, and detect therapeutic effects or safety concerns. This study explores the extent to which BMs are utilized in the development of treatments for neurodegenerative diseases (NDDs), as well as ...
Audrey M. M. Hermans+8 more
wiley +1 more source
Dopa-responsive dystonia and hyperprolactinaemia : a novel association in two sisters [PDF]
Dopa-Responsive Dystonia (DRD) is a rare hereditary condition of childhood-onset dystonia which responds dramatically to treatment with levodopa. It was first described in 1971 as a "hereditary progressive basal ganglia disease with marked diurnal ...
Cachia, Mario J., Galea, Janabel
core
Determination of Urinary Neopterin/Creatinine Ratio to Distinguish Active Tuberculosis from Latent Mycobacterium tuberculosis Infection. [PDF]
BACKGROUND: Biomarkers to distinguish latent from active Mycobacterium (M.) tuberculosis infection in clinical practice are lacking. The urinary neopterin/creatinine ratio can quantify the systemic interferon-gamma effect in patients with M. tuberculosis
Eisenhut, M+5 more
core +3 more sources
Analytical validation of an enzyme immunoassay for the extraction and measurement of secretory immunoglobulin A in feces of redfronted lemurs (Eulemur rufifrons), confirmed the existence of sIgA in lemurs and concentration stability of frozen extracts at –20°C for at least 3 months. ABSTRACT The measurement of biomarkers in blood and excreta can enable
Leonie Pethig+4 more
wiley +1 more source
Urinary neopterin concentrations in patients with Balkan endemic nephropathy (BEN) [PDF]
Urinary neopterin concentrations in patients with Balkan endemic nephropathy (BEN).BackgroundBalkan endemic nephropathy (BEN) is of great clinical importance in restricted areas of Bulgaria, Serbia, Croatia, Bosnia, Herzegovina, and Romania, since the ...
Atanassova, Srebrena+6 more
core +1 more source
Neopterin and Kynurenine in Mesangioproliferative Glomerulonephritis
Summary Serum kynurenine and neopterin concentrations were determined in patients with chronic mesangioproliferative glomerulonephritis with normal renal function and in patients with chronic renal failure. Significantly increased kynurenine and neopterin levels have been observed in 28% of mesangioproliferative glomerulonephritis patients.
Bernhard Widner+3 more
openaire +3 more sources
Procalcitonin and Neopterin in Infectious Diseases
Summary Procalcitonin, a new inflammation parameter, has been shown to be markedly increased in patients with severe bacterial and parasitic infections, septic shock, and multiple organ failure. In contrast, in severe viral infections or inflammatory reactions of non-infectious origin (e.g.
Petra Innerhofer+4 more
openaire +2 more sources
Diagnosis of tetrahydrobiopterin deficiency using filter paper blood spots: further development of the method and 5 years experience [PDF]
In every newborn with even mild hyperphenylalaninemia (HPA) tetrahydrobiopterin (BH4) deficiencies need to be excluded as soon as possible. Differential diagnosis is most commonly performed by analysis of urinary neopterin and biopterin.
Abu Seda, Bettina+5 more
core
Interventions for neurocognitive dysfunction [PDF]
Purpose of review: To evaluate current barriers to HIV cure strategies and interventions for neurocognitive dysfunction with a particular focus on recent advancements over the last three years. Recent findings: Optimal anti-retroviral therapy (ART) poses
Brew, B, Ellero, J, Lubomski, M
core +2 more sources
Determination of neopterin in serum and urine.
Abstract Concentrations of neopterin, a product of activated macrophages, in serum from 662 apparently healthy individuals (ages 1 to 97 years, median 22 years) were measured by radioimmunoassay and the results statistically analyzed. Consistent with prior investigations on the urinary excretion of neopterin, we found no significant sex ...
H. Hetzel+8 more
openaire +3 more sources