Results 61 to 70 of about 22,017 (305)

Metabolomics Identifies multiple candidate biomarkers to diagnose and stage human African trypanosomiasis [PDF]

, 2016
Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the disease (stage 1 defined by parasites being present in blood and lymphatics whilst for stage 2, parasites are found beyond the
Barrett, Michael P., Bisser, Sylvie, Biéler, Sylvain, Cattanach, Amy M., Courtioux, Bertrand, Daly, Rónán, Ndung’u, Joseph M., Vincent, Isabel M.   +7 more
core   +5 more sources

Determination of Urinary Neopterin/Creatinine Ratio to Distinguish Active Tuberculosis from Latent Mycobacterium tuberculosis Infection. [PDF]

, 2016
BACKGROUND: Biomarkers to distinguish latent from active Mycobacterium (M.) tuberculosis infection in clinical practice are lacking. The urinary neopterin/creatinine ratio can quantify the systemic interferon-gamma effect in patients with M. tuberculosis
Eisenhut, M, Hargreaves, DS, Housley, D, Mulla, R, Scott, A, Walters, A   +5 more
core   +8 more sources

Neopterin and 7,8-dihydroneopterin are generated within atherosclerotic plaques

Pteridines, 2015
Plasma neopterin correlates with the level of cardiovascular disease. Neopterin is the oxidation product of 7,8-dihydroneopterin, which is released by γ-interferon-stimulated macrophages. 7,8-Dihydroneopterin is a potent antioxidant, which inhibits lipid
Janmale Tejraj, Genet Rebecca, Crone Elizabeth, Flavall Elizabeth, Firth Carol, Pirker John, Roake Justin A., Gieseg Steven P.   +7 more
doaj   +1 more source

Neopterin serum level does not reflect the disease activity in rheumatoid arthritis: A systematic review and meta‐analysis

IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2020
Rheumatoid arthritis (RA) is a chronic autoimmune disease caused by established chronic inflammation. Neopterin levels have extensively been considered as a marker of immune activation during inflammation.
Alireza Hejrati, M. Taghadosi, Reza Alizadeh-Navaei, S. Hosseinzadeh, D. Bashash, Mozhgan Esmaili, P. Zafari   +6 more
semanticscholar   +1 more source

The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question [PDF]

, 2017
Human African trypanosomiasis (HAT), also known as sleeping sickness, puts millions of people at risk in sub-Saharan Africa and is a neglected parasitic disease that is almost always fatal if untreated or inadequately treated. HAT manifests itself in two
Gettinby, George, Kennedy, Peter G.E., Njamnshi, Alfred K.   +2 more
core   +1 more source

Influence of Three Different Diet Modes Combined with Exercise Loads on Urinary and Plasma Neopterin Concentrations: A Longitudinal Study

Pteridines, 1997
During six months, we studied the influence of three extremely different diet modes (normal diet, carbohydrate- rich diet, fat-rich diet) combined with three defined exercise loads (step test, endurance test fo r 30 minutes, endurance test for 90 minutes)
Lamprecht Manfred, Mlekusch Walter, Vrecko Karoline, Reibnegger Gilbert   +3 more
doaj   +1 more source

Effect of Neopterin on the Hematopoietic System

Pteridines, 2009
Neopterin is produced by monocytes and is a useful biomarker for inflammation. We recently found that neopterin is biologically active against hematopoiesis during inflammatory processes.
Tsuboi Isao, Aizawa Shin
doaj   +1 more source

Urinary Neopterin in Malignant Lymphoma

The International Journal of Biological Markers, 1991
Urinary neopterin levels were studied in 96 patients with malignant lymphomas. Twenty-eight had Hodgkin's disease and 68 non-Hodgkin's lymphoma. Neopterin excretion was significantly related to the clinical stage of the disease. Mean neopterin excretion in patients with active disease (634 ± 527 μmol neopterin/mol creatinine) was significantly higher (
PICCININI, Lino, Zironi S., FEDERICO, Massimo, PINI, Luigi Alberto, Luppi G.   +4 more
openaire   +3 more sources

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 287-294, February 2026.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve, Claire‐Marine Bérat, Sylvain Hanein, Cyril Gitiaux, ATAD3 Study Group, Julie Steffann, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia, Brian Sperelakis‐Beedham, Zahra Assouline, Marie‐Thérèse Abi‐Warde, Rukhshona Abdullazoda, Agnès Guichet, Céline Bris, Aurélien Caux, Marlène Rio, Jérémy Bertrand, Pauline Gaignard, Alice Lepelley, Arnold Munnich, Manuel Schiff, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia   +26 more
wiley   +1 more source

Urinary Neopterin in Patients with Diabetes Mellitus and Foot Ulcers

Pteridines, 2007
Increased urinary or serum concentrations of neopterin have been reported in disorders associated with systemic immune activation, e.g. viral infections, cancer, or autoimmune diseases, but the data on neopterin concentrations in patients with diabetes ...
Melicharova Karolina, Kusalova Marie, Smahelova Alena, Hyspler Radomir, Solichova Dagmar, Melichar Bohuslav   +5 more
doaj   +1 more source