Results 11 to 20 of about 34,514 (311)

Successful Use of Conbercept to Treat Choroidal Neovascularization: A Case Report

Case Reports in Ophthalmology, 2022
Chronic urticaria is a dermatological condition characterized by the appearance of wheals or angioedema longer than 6 weeks. It could cause serious complications such as laryngeal edema, vasculitis, and diarrhea.
Jin Yang, Zheng Liu, Tao Liu
doaj   +1 more source

Evaluation of a novel deep learning based screening system for pathologic myopia [PDF]

International Journal of Ophthalmology, 2023
AIM: To evaluate the clinical application value of the artificial intelligence assisted pathologic myopia (PM-AI) diagnosis model based on deep learning. METHODS: A total of 1156 readable color fundus photographs were collected and annotated based on the
Pei-Fang Ren, Xu-Yuan Tang, Chen-Ying Yu, Li-Li Zhu, Wei-Hua Yang, Ye Shen   +5 more
doaj   +1 more source

ADAM9 Is Involved in Pathological Retinal Neovascularization [PDF]

Molecular and Cellular Biology, 2009
Pathological ocular neovascularization, caused by diabetic retinopathy, age-related macular degeneration, or retinopathy of prematurity, is a leading cause of blindness, yet much remains to be learned about its underlying causes. Here we used oxygen-induced retinopathy (OIR) and laser-induced choroidal neovascularization (CNV) to assess the ...
Victor, Guaiquil, Steven, Swendeman, Tsunehiko, Yoshida, Sai, Chavala, Peter A, Campochiaro, Carl P, Blobel   +5 more
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Lipid Mediators, M2 Macrophages, and Pathological Neovascularization [PDF]

Trends in Molecular Medicine, 2018
Sasaki and colleagues [1] (JCI Insight 2018;3,e96902) identified the leukocyte inflammatory lipid mediator leukotriene B4 (LTB4)/LTB4 receptor 1 receptor-signaling axis in M2 macrophages as a causal pathway for the vascular endothelial growth factor-dependent pathological neovascularization in a mouse model that mimics wet age-related macular ...
Steven L, Swendeman, Timothy, Hla
openaire   +2 more sources

Myeloid lineage contributes to pathological choroidal neovascularization formation via SOCS3 [PDF]

EBioMedicine, 2021
Pathological neovascularization in neovascular age-related macular degeneration (nAMD) is the leading cause of vision loss in the elderly. Increasing evidence shows that cells of myeloid lineage play important roles in controlling pathological endothelium formation.
Tianxi Wang, Pingzhu Zhou, Xuemei Xie, Yohei Tomita, Steve Cho, Demetrios Tsirukis, Enton Lam, Hongbo Robert Luo, Ye Sun   +8 more
openaire   +4 more sources

An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

BMC Molecular and Cell Biology, 2020
Background Transplantation of gene transfected endothelial progenitor cells (EPCs) has provided novel methods for tumor neovascularization therapy but not for ocular disease therapy.
Jing Ai, Jian Ma, Zhi-Qing Chen, Jun-Hui Sun, Ke Yao   +4 more
doaj   +1 more source

Specific ablation of PDGFRβ-overexpressing pericytes with antibody-drug conjugate potently inhibits pathologic ocular neovascularization in mouse models

Communications Medicine, 2021
Lee et al. use an antibody-drug conjugate to treat pathologic ocular neovascularization in mouse models. The antibody-drug conjugate targets PDGFRβ-expressing pericytes, with similar therapeutic effects to an anti-VEGF agent and with limited unwanted ...
Seok Jae Lee, Soohyun Kim, Dong Hyun Jo, Chang Sik Cho, Su Ree Kim, Dongmin Kang, Jisu Chae, Duck Kyun Yoo, Suji Ha, Junho Chung, Jeong Hun Kim   +10 more
doaj   +1 more source

Sema3f Protects Against Subretinal Neovascularization In Vivo

EBioMedicine, 2017
Pathological neovascularization of the outer retina is the hallmark of neovascular age-related macular degeneration (nAMD). Building on our previous observations that semaphorin 3F (Sema3f) is expressed in the outer retina and demonstrates anti ...
Ye Sun, Raffael Liegl, Yan Gong, Anima Bühler, Bertan Cakir, Steven S. Meng, Samuel B. Burnim, Chi-Hsiu Liu, Tristan Reuer, Peipei Zhang, Johanna M. Walz, Franziska Ludwig, Clemens Lange, Hansjürgen Agostini, Daniel Böhringer, Günther Schlunck, Lois E.H. Smith, Andreas Stahl   +17 more
doaj   +1 more source

Angiogenesis in squamous precancerous cervical lesions [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. Vascularisation is one of basic tumor's characteristics. Neoangiogenesis starts at the stage of the dysplastic epithelial changes, thus before the progression into invasive lesion. This study was designed to determine the relation between
Panjković Milan, Ivković-Kapicl Tatjana   +1 more
doaj   +1 more source

Tendinopathy—from basic science to treatment [PDF]

, 2008
Chronic tendon pathology (tendinopathy), although common, is difficult to treat. Tendons possess a highly organized fibrillar matrix, consisting of type I collagen and various 'minor' collagens, proteoglycans and glycoproteins.
A McCormick, AH Drummond, AJ Banes, AN Bamji, AN Corps, AN Corps, AN Corps, AP D'Vaz, B Pasternak, BL Woodley, BM Clancy, CA Speed, D Bjur, EM Badley, G Puddu, G Riley, GAC Murrell, GC Jones, GC Jones, GP Riley, GP Riley, Graham Riley, H Alfredson, H Alfredson, H Alfredson, H Alfredson, H Alfredson, H Langberg, H Langberg, H Langberg, H Nagase, HA Awad, J Archambault, JA Paoloni, JA Paoloni, JA Paoloni, JD Rompe, JE Carpenter, JL Cook, JM Archambault, L Józsa, L Ohberg, LC Almekinders, LJ McCawley, M Aström, M Benjamin, M Gotoh, M Gotoh, M Lavagnino, M Lavagnino, MD Chard, ME Jones, MH Khan, N Mafi, P Burssens, P Kannus, R Salingcarnboriboon, RA Bank, RF Ker, RK Smith, SA Fenwick, SC Fu, SG Rees, SP Arnoczky, T Pufe, T Pufe, T Samiric, TG Gerich, TW Ehlers, UM Wewer   +69 more
core   +1 more source