Results 31 to 40 of about 125,954 (295)

El cáncer en la función mitocondrial

open access: yesRevista de la Facultad de Medicina, 2018
Metabolism alterations are associated with the loss of mitochondrial function in tumor cells. Current research discuss whether such loss is evident in function itself, or if cells can provide maximum stability to its functions. More studies are needed to
Sofía Isabel Freyre-Bernal   +4 more
doaj   +1 more source

Oxidative and Nitrosative Stress in Age-Related Macular Degeneration: A Review of Their Role in Different Stages of Disease

open access: yesAntioxidants, 2021
Although the exact pathogenetic mechanisms leading to age-related macular degeneration (AMD) have not been clearly identified, oxidative damage in the retina and choroid due to an imbalance between local oxidants/anti-oxidant systems leading to chronic ...
Caterina Toma   +4 more
doaj   +1 more source

Histological changes secondary to use of anti-angiogenic therapy after interruption of vasa vasorum flow in the descending aorta: results in a porcine model

open access: yesJornal Vascular Brasileiro, 2019
Background Anti-angiogenic regulators may have therapeutic implications for onset and progression of atherosclerosis. Objectives To demonstrate histological changes secondary to the use of bevacizumab in the aorta of pigs after interruption of flow in ...
Cyro Castro Júnior   +1 more
doaj   +1 more source

Management of Myopic Maculopathy: A Review

open access: yesTürk Oftalmoloji Dergisi, 2023
Myopia, including pathologic myopia, has seen a significant increase in prevalence in recent years. It is a significant cause of irreversible vision loss worldwide and prediction models demonstrate the substantial future impact on the population.
William J. Anderson, Levent Akduman
doaj   +1 more source

Key Multimodal Fundus Imaging Findings to Recognize Multifocal Choroiditis in Patients With Pathological Myopia

open access: yesFrontiers in Medicine, 2022
Myopia represents a major socioeconomic burden with an increasing prevalence worldwide. Pathologic myopia refers to myopic patients with structural changes in the posterior pole including different patterns of chorioretinal atrophy, choroidal ...
Roberto Gallego-Pinazo   +2 more
doaj   +1 more source

Angiofluorographic Characteristics of Choroidal Neovascularization associated with Pathologic Myopia

open access: yesromanian journal of ophthalmology, 2020
Purpose: To evaluate the incidence of choroidal neovascularization (CNV) in high myopic patients who experienced recent visual loss and to describe the characteristics of CNV that develop as a complication of pathologic myopia and were detected by fluorescein angiography (FA).
Tomi, Anca, Ştefan, Irina
openaire   +3 more sources

Thymidine phosphorylase and its possible correlation with the lung cancer phenotype features

open access: yesPatologìâ, 2015
The tumor phenotype investigation is necessary for lung cancer drug therapy optimization. For this purpose is perspective to use the biochemical markers of angiogenesis. Thymidine phosphorylase may be one of them. Aim. The aim of study was to evaluate
E. M. Bakurova   +5 more
doaj   +1 more source

Suppression of pathological ocular neovascularization by a small molecule, SU1498

open access: yesBiomedicine & Pharmacotherapy, 2020
Selective inhibition of vascular endothelial growth factor receptor (VEGFR), particularly VEGFR-2, is an efficient method for the treatment of ocular neovascularization. SU1498 is a specific inhibitor of VEGFR-2. In this study, we investigated the role of SU1498 in ocular neovascularization.
Tao, Shu-Ya   +4 more
openaire   +2 more sources

FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice

open access: yesCell Reports, 2017
Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration.
Zhongjie Fu   +12 more
doaj   +1 more source

Intravitreal conbercept for choroidal neovascularisation secondary to pathological myopia in a real‐world setting in China

open access: yesBMC Ophthalmology, 2021
Background To evaluate the 12-month efficacy and safety of intravitreal conbercept for myopic choroidal neovascularization (CNV). Methods A retrospective, observational study.
Xin Nie   +3 more
doaj   +1 more source

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