Predictors of pathologic stage in prostatic carcinoma. The role of neovascularity [PDF]
Prostate adenocarcinoma is a significant cause of morbidity and mortality in older men. However, the histologic prevalence far exceeds clinically manifest disease. Increased screening has resulted in the detection of a large number of carcinomas of unknown malignant potential.
M K, Brawer +4 more
openaire +2 more sources
Thymidine phosphorylase and its possible correlation with the lung cancer phenotype features
The tumor phenotype investigation is necessary for lung cancer drug therapy optimization. For this purpose is perspective to use the biochemical markers of angiogenesis. Thymidine phosphorylase may be one of them. Aim. The aim of study was to evaluate
E. M. Bakurova +5 more
doaj +1 more source
Evidence for mechanisms underlying the functional benefits of a myocardial matrix hydrogel for post-MI treatment [PDF]
Background There is increasing need for better therapies to prevent the development of heart failure after myocardial infarction (MI). An injectable hydrogel derived from decellularized porcine ventricular myocardium has been shown to halt the post ...
Braden, Rebecca L. +8 more
core +1 more source
Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core +1 more source
Management of Myopic Maculopathy: A Review
Myopia, including pathologic myopia, has seen a significant increase in prevalence in recent years. It is a significant cause of irreversible vision loss worldwide and prediction models demonstrate the substantial future impact on the population.
William J. Anderson, Levent Akduman
doaj +1 more source
Angiofluorographic Characteristics of Choroidal Neovascularization associated with Pathologic Myopia
Purpose: To evaluate the incidence of choroidal neovascularization (CNV) in high myopic patients who experienced recent visual loss and to describe the characteristics of CNV that develop as a complication of pathologic myopia and were detected by fluorescein angiography (FA).
Tomi, Anca, Ştefan, Irina
openaire +3 more sources
FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice
Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration.
Zhongjie Fu +12 more
doaj +1 more source
Background To evaluate the 12-month efficacy and safety of intravitreal conbercept for myopic choroidal neovascularization (CNV). Methods A retrospective, observational study.
Xin Nie +3 more
doaj +1 more source
Multidimensional en-face OCT imaging of the retina. [PDF]
Fast T-scanning (transverse scanning, en-face) was used to build B-scan or C-scan optical coherence tomography (OCT) images of the retina. Several unique signature patterns of en-face (coronal) are reviewed in conjunction with associated confocal images ...
Adrian G. Podoleanu +34 more
core +1 more source
Suppression of pathological ocular neovascularization by a small molecule, SU1498
Selective inhibition of vascular endothelial growth factor receptor (VEGFR), particularly VEGFR-2, is an efficient method for the treatment of ocular neovascularization. SU1498 is a specific inhibitor of VEGFR-2. In this study, we investigated the role of SU1498 in ocular neovascularization.
Tao, Shu-Ya +4 more
openaire +2 more sources

