Results 41 to 50 of about 26,618 (266)
STUDIES OF MOLECULAR CHANGES IN INTERVERTEBRAL DISC DEGENERATION IN ANIMAL MODEL [PDF]
Acta Ortopédica Brasileira, 2016 Objective: To evaluate the structural and molecular changes in the extracellular matrix (ECM) during the process of intervertebral disc degeneration, using animal model.
Marcelo Ferraz de Campos +5 more
doaj +2 more sources
Advanced Materials, EarlyView.Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello +5 more
wiley +1 more source
International Journal of Ophthalmology, 2013 AIM: To evaluate the visual outcomes of choroidal neovascularization (CNV) secondary to pathological myopia and the impact of novel risk factors affecting the final visual outcome.
Tock-Han Lim +3 more
doaj +1 more source
Macrophage Sult2b1 promotes pathological neovascularization in age-related macular degeneration
Life Science Alliance, 2023 Sult2b1 deficiency attenuates pathologic neovascularization by inhibiting M2 macrophage polarization and promoting cholesterol efflux via the LXR–ABCA1/G1 pathway. Disordered immune responses and cholesterol metabolism have been implicated in age-related
Yafang Wang +8 more
doaj +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
ANTI-ANGIOGENIC THERAPY IN PATIENTS WITH PATHOLOGIC MYOPIA AND CHOROIDAL NEOVASCULARIZATION
Acta Biomedica Scientifica, 2016 Purpose of the study: to study the efficacy and safety of Ranibizumab in patients with pathologic myopia and choroidal neovascularization (CNV). 22 patients (22 eyes) with myopic CNV were included in the study.
S. A. Korotkikh +4 more
doaj +1 more source
Management of Choroidal Neovascularization Secondary to Pathological Myopia
Asia-Pacific Journal of Ophthalmology, 2014 Choroidal neovascularization (CNV) secondary to pathological myopia is an important cause of significant visual impairment in young adults. High myopia is particularly prevalent in Asian population. New scientific contributions have been made to the understanding of high myopia and myopic CNV.
Mary, Ho +3 more
openaire +2 more sources
Advanced Materials, EarlyView.This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris +11 more
wiley +1 more source
Perfil epidemiológico das aplicações intravítreas de Ranibizumab
Revista Brasileira de OftalmologiaResumo Objetivo: O objetivo desse trabalho é avaliar o perfil de aplicações intravítreas do Ranibizumab em uma população de adultos atendidos no Instituto Benjamin Constant, no ano de 2015, levando em consideração o efeito sobre a acuidade visual e a ...
Gabriela dos Santos Souza Barros +4 more
doaj +1 more source
Macrophages inhibit neovascularization in a murine model of age-related macular degeneration. [PDF]
PLoS Medicine, 2006 Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 y of age in at least three continents. Choroidal neovascularization (CNV) is the process by which abnormal blood vessels develop underneath the retina.
Rajendra S Apte +3 more
doaj +1 more source