Results 41 to 50 of about 26,143 (267)

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Factors affecting visual outcome of myopic choroidal neovascularization treated with verteporfin photodynamic therapy

International Journal of Ophthalmology, 2013
AIM: To evaluate the visual outcomes of choroidal neovascularization (CNV) secondary to pathological myopia and the impact of novel risk factors affecting the final visual outcome.
Tock-Han Lim, Kai-Hung Lim, Milton C. Chew, Colin S. Tan   +3 more
doaj   +1 more source

Macrophage Sult2b1 promotes pathological neovascularization in age-related macular degeneration

Life Science Alliance, 2023
Sult2b1 deficiency attenuates pathologic neovascularization by inhibiting M2 macrophage polarization and promoting cholesterol efflux via the LXR–ABCA1/G1 pathway. Disordered immune responses and cholesterol metabolism have been implicated in age-related
Yafang Wang, Yang Liu, Yan Wang, Yidong Wu, Zhixuan Chen, Feng Wang, Xiaoling Wan, Fenghua Wang, Xiaodong Sun   +8 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

ANTI-ANGIOGENIC THERAPY IN PATIENTS WITH PATHOLOGIC MYOPIA AND CHOROIDAL NEOVASCULARIZATION

Acta Biomedica Scientifica, 2016
Purpose of the study: to study the efficacy and safety of Ranibizumab in patients with pathologic myopia and choroidal neovascularization (CNV). 22 patients (22 eyes) with myopic CNV were included in the study.
S. A. Korotkikh, E. V. Bobykin, G. V. Zhiborkin, A. Y. Anashkin, A. V. Berezin   +4 more
doaj   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Perfil epidemiológico das aplicações intravítreas de Ranibizumab

Revista Brasileira de Oftalmologia
Resumo Objetivo: O objetivo desse trabalho é avaliar o perfil de aplicações intravítreas do Ranibizumab em uma população de adultos atendidos no Instituto Benjamin Constant, no ano de 2015, levando em consideração o efeito sobre a acuidade visual e a ...
Gabriela dos Santos Souza Barros, Alléxya Affonso Antunes Marcos, Gabriella Nogueira Moraes, Eduardo Henrique Morizot Leite, Abelardo de Souza Couto Junior   +4 more
doaj   +1 more source

Macrophages inhibit neovascularization in a murine model of age-related macular degeneration. [PDF]

PLoS Medicine, 2006
Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 y of age in at least three continents. Choroidal neovascularization (CNV) is the process by which abnormal blood vessels develop underneath the retina.
Rajendra S Apte, Jennifer Richter, John Herndon, Thomas A Ferguson   +3 more
doaj   +1 more source

FGF2-induced STAT3 activation regulates pathologic neovascularization

Experimental Eye Research, 2019
Cell-autonomous endothelial cell (EC) fibroblast growth factor receptor (FGFR) signaling through FGFR1/2 is essential for injury-induced wound vascularization and pathologic neovascularization as in blinding eye diseases such as age-related macular degeneration. Which FGF ligand(s) is critical in regulating angiogenesis is unknown.
Zhenyu, Dong, Andrea, Santeford, Norimitsu, Ban, Tae Jun, Lee, Craig, Smith, David M, Ornitz, Rajendra S, Apte   +6 more
openaire   +3 more sources

Irisin Attenuates Pathological Neovascularization in Oxygen-Induced Retinopathy Mice

Investigative Opthalmology & Visual Science, 2022
Abnormal angiogenesis is a defining feature in a couple of ocular neovascular diseases. The application of anti-VEGFA therapy has achieved certain benefits in the clinic, accompanying side effects and poor responsiveness in many patients. The present study investigated the role of irisin in retinal neovascularization.Western blot and quantitative PCR ...
Zhang, Jieqiong, Liu, Zhifei, Wu, Haoqian, Chen, Xi, Hu, Qiumei, Li, Xue, Luo, Linlin, Ye, Shiyang, Ye, Jian   +8 more
openaire   +2 more sources