Results 11 to 20 of about 34,701 (312)

Factors associated with the recurrence of choroidal neovascularization in pathologic myopia

Frontiers in Medicine, 2022
PurposeTo investigate the factors associated with the recurrence of pathologic myopia choroidal neovascularization (PM-CNV).MethodsForty-eight eyes of 48 patients with PM-CNV treated with conbercept at least 6 months of follow-up were included ...
Ruixia Jing, Yuxia Bo, Lei Gao, Zhen Wang   +3 more
doaj   +3 more sources

ADAM9 Is Involved in Pathological Retinal Neovascularization [PDF]

Molecular and Cellular Biology, 2009
Pathological ocular neovascularization, caused by diabetic retinopathy, age-related macular degeneration, or retinopathy of prematurity, is a leading cause of blindness, yet much remains to be learned about its underlying causes. Here we used oxygen-induced retinopathy (OIR) and laser-induced choroidal neovascularization (CNV) to assess the ...
Victor, Guaiquil, Steven, Swendeman, Tsunehiko, Yoshida, Sai, Chavala, Peter A, Campochiaro, Carl P, Blobel   +5 more
openaire   +2 more sources

Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2019
Objective— Pathological neovascularization is crucial for progression and morbidity of serious diseases such as cancer, diabetic retinopathy, and age-related macular degeneration. While mechanisms of ongoing pathological neovascularization have been extensively studied, the initiating pathological vascular remodeling (PVR ...
Ali, Zaheer, Mukwaya, Anthony, Biesemeier, Antje, Ntzouni, Maria, Ramsköld, Daniel, Giatrellis, Sarantis, Mammadzada, Parviz, Cao, Renhai, Lennikov, Anton, Marass, Michele, Gerri, Claudia, Hildesjö, Camilla, Taylor, Michael, Deng, Qiaolin, Peebo, Beatrice, del Peso, Luis, Kvanta, Anders, Sandberg, Rickard, Schraermeyer, Ulrich, Andre, Helder, Steffensen, John F., Lagali, Neil, Cao, Yihai, Kele, Julianna, Jensen, Lasse Dahl   +24 more
openaire   +8 more sources

Interleukin-18 regulates pathological intraocular neovascularization [PDF]

Journal of Leukocyte Biology, 2007
AbstractRecently, the proinflammatory cytokine IL-18 has been shown to have a role in angiogenesis. This study aimed to elucidate its role in abnormal neovascularization (NV) in an oxygen-induced retinopathy (OIR) mouse model of the retinopathy seen in human premature newborns.
Hong, Qiao, Koh-Hei, Sonoda, Yasuhiro, Ikeda, Takeru, Yoshimura, Kuniaki, Hijioka, Young-Joon, Jo, Yukio, Sassa, Chikako, Tsutsumi-Miyahara, Yasuaki, Hata, Shizuo, Akira, Tatsuro, Ishibashi   +10 more
openaire   +2 more sources

Lipid Mediators, M2 Macrophages, and Pathological Neovascularization [PDF]

Trends in Molecular Medicine, 2018
Sasaki and colleagues [1] (JCI Insight 2018;3,e96902) identified the leukocyte inflammatory lipid mediator leukotriene B4 (LTB4)/LTB4 receptor 1 receptor-signaling axis in M2 macrophages as a causal pathway for the vascular endothelial growth factor-dependent pathological neovascularization in a mouse model that mimics wet age-related macular ...
Steven L, Swendeman, Timothy, Hla
openaire   +2 more sources

Sema3f Protects Against Subretinal Neovascularization In Vivo

EBioMedicine, 2017
Pathological neovascularization of the outer retina is the hallmark of neovascular age-related macular degeneration (nAMD). Building on our previous observations that semaphorin 3F (Sema3f) is expressed in the outer retina and demonstrates anti ...
Ye Sun, Raffael Liegl, Yan Gong, Anima Bühler, Bertan Cakir, Steven S. Meng, Samuel B. Burnim, Chi-Hsiu Liu, Tristan Reuer, Peipei Zhang, Johanna M. Walz, Franziska Ludwig, Clemens Lange, Hansjürgen Agostini, Daniel Böhringer, Günther Schlunck, Lois E.H. Smith, Andreas Stahl   +17 more
doaj   +1 more source

Significance of microvessel density in prostate cancer core biopsy [PDF]

Vojnosanitetski Pregled, 2015
Background/Aim. In prostate tumors, angiogenesis, measured as microvessel density, is associated with tumor stage and Gleason score. The aim of this study was determine neovascularization of prostatic adenocarcinomas in core biopsies and ...
Salapura-Dugonjić Aleksandra, Knežević-Ušaj Slavica, Eri Živka, Tadić-Latinović Ljiljana   +3 more
doaj   +1 more source

Tendinopathy—from basic science to treatment [PDF]

, 2008
Chronic tendon pathology (tendinopathy), although common, is difficult to treat. Tendons possess a highly organized fibrillar matrix, consisting of type I collagen and various 'minor' collagens, proteoglycans and glycoproteins.
A McCormick, AH Drummond, AJ Banes, AN Bamji, AN Corps, AN Corps, AN Corps, AP D'Vaz, B Pasternak, BL Woodley, BM Clancy, CA Speed, D Bjur, EM Badley, G Puddu, G Riley, GAC Murrell, GC Jones, GC Jones, GP Riley, GP Riley, Graham Riley, H Alfredson, H Alfredson, H Alfredson, H Alfredson, H Alfredson, H Langberg, H Langberg, H Langberg, H Nagase, HA Awad, J Archambault, JA Paoloni, JA Paoloni, JA Paoloni, JD Rompe, JE Carpenter, JL Cook, JM Archambault, L Józsa, L Ohberg, LC Almekinders, LJ McCawley, M Aström, M Benjamin, M Gotoh, M Gotoh, M Lavagnino, M Lavagnino, MD Chard, ME Jones, MH Khan, N Mafi, P Burssens, P Kannus, R Salingcarnboriboon, RA Bank, RF Ker, RK Smith, SA Fenwick, SC Fu, SG Rees, SP Arnoczky, T Pufe, T Pufe, T Samiric, TG Gerich, TW Ehlers, UM Wewer   +69 more
core   +1 more source

Potential Role for ADAM15 in Pathological Neovascularization in Mice [PDF]

Molecular and Cellular Biology, 2003
ADAM15 (named for a disintegrin and metalloprotease 15, metargidin) is a membrane-anchored glycoprotein that has been implicated in cell-cell or cell-matrix interactions and in the proteolysis of molecules on the cell surface or extracellular matrix.
Keisuke, Horiuchi, Gisela, Weskamp, Lawrence, Lum, Hans-Peter, Hammes, Hui, Cai, Thomas A, Brodie, Thomas, Ludwig, Riccardo, Chiusaroli, Roland, Baron, Klaus T, Preissner, Katia, Manova, Carl P, Blobel   +11 more
openaire   +2 more sources

Angiogenesis in squamous precancerous cervical lesions [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. Vascularisation is one of basic tumor's characteristics. Neoangiogenesis starts at the stage of the dysplastic epithelial changes, thus before the progression into invasive lesion. This study was designed to determine the relation between
Panjković Milan, Ivković-Kapicl Tatjana   +1 more
doaj   +1 more source