Results 21 to 30 of about 34,514 (311)

Significance of microvessel density in prostate cancer core biopsy [PDF]

open access: yesVojnosanitetski Pregled, 2015
Background/Aim. In prostate tumors, angiogenesis, measured as microvessel density, is associated with tumor stage and Gleason score. The aim of this study was determine neovascularization of prostatic adenocarcinomas in core biopsies and ...
Salapura-Dugonjić Aleksandra   +3 more
doaj   +1 more source

Irisin Attenuates Pathological Neovascularization in Oxygen-Induced Retinopathy Mice

open access: yesInvestigative Opthalmology & Visual Science, 2022
Abnormal angiogenesis is a defining feature in a couple of ocular neovascular diseases. The application of anti-VEGFA therapy has achieved certain benefits in the clinic, accompanying side effects and poor responsiveness in many patients. The present study investigated the role of irisin in retinal neovascularization.Western blot and quantitative PCR ...
Zhang, Jieqiong   +8 more
openaire   +2 more sources

Factors associated with the recurrence of choroidal neovascularization in pathologic myopia

open access: yesFrontiers in Medicine, 2022
PurposeTo investigate the factors associated with the recurrence of pathologic myopia choroidal neovascularization (PM-CNV).MethodsForty-eight eyes of 48 patients with PM-CNV treated with conbercept at least 6 months of follow-up were included ...
Ruixia Jing   +3 more
doaj   +1 more source

Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. [PDF]

open access: yes, 2011
Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues.
Dickson, Patricia I   +6 more
core   +3 more sources

Co-existent choroidal neovascular membrane and macular hole in pathologic myopia:a long follow-up clinical outcome and literature review

open access: yesInternational Journal of Ophthalmology, 2013
Choroidal neovascularization (CNV) is an uncommon complication associated with a macular hole. In this case report of a rare condition, we present a pathologic myopia patient with a co-existent macular hole and choroidal neovascular membrane. The patient
Zhi-Qing Chen   +4 more
doaj   +1 more source

Oxidative and Nitrosative Stress in Age-Related Macular Degeneration: A Review of Their Role in Different Stages of Disease

open access: yesAntioxidants, 2021
Although the exact pathogenetic mechanisms leading to age-related macular degeneration (AMD) have not been clearly identified, oxidative damage in the retina and choroid due to an imbalance between local oxidants/anti-oxidant systems leading to chronic ...
Caterina Toma   +4 more
doaj   +1 more source

El cáncer en la función mitocondrial

open access: yesRevista de la Facultad de Medicina, 2018
Metabolism alterations are associated with the loss of mitochondrial function in tumor cells. Current research discuss whether such loss is evident in function itself, or if cells can provide maximum stability to its functions. More studies are needed to
Sofía Isabel Freyre-Bernal   +4 more
doaj   +1 more source

Long-term follow-up of myopic choroidal neovascularization treated with ranibizumab [PDF]

open access: yes, 2011
PURPOSE: To evaluate the long-term safety and efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (CNV). METHODS: Three-year retrospective, nonrandomized, interventional case series.
Cachulo, ML   +6 more
core   +1 more source

Reduced Retinal Microvascular Density, Improved Forepaw Reach, Comparative Microarray and Gene Set Enrichment Analysis with c-jun Targeting DNA Enzyme [PDF]

open access: yes, 2015
Retinal neovascularization is a critical component in the pathogenesis of common ocular disorders that cause blindness, and treatment options are limited.
Chan, Cecilia W. S   +3 more
core   +1 more source

FGF2-induced STAT3 activation regulates pathologic neovascularization

open access: yesExperimental Eye Research, 2019
Cell-autonomous endothelial cell (EC) fibroblast growth factor receptor (FGFR) signaling through FGFR1/2 is essential for injury-induced wound vascularization and pathologic neovascularization as in blinding eye diseases such as age-related macular degeneration. Which FGF ligand(s) is critical in regulating angiogenesis is unknown.
Zhenyu, Dong   +6 more
openaire   +3 more sources

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