Results 31 to 40 of about 1,067,090 (283)
Potential Role for ADAM15 in Pathological Neovascularization in Mice [PDF]
Molecular and Cellular Biology, 2003 ADAM15 (named for a disintegrin and metalloprotease 15, metargidin) is a membrane-anchored glycoprotein that has been implicated in cell-cell or cell-matrix interactions and in the proteolysis of molecules on the cell surface or extracellular matrix.
Lawrence G. Lum +13 more
openaire +3 more sources
Sema3f Protects Against Subretinal Neovascularization In Vivo
EBioMedicine, 2017 Pathological neovascularization of the outer retina is the hallmark of neovascular age-related macular degeneration (nAMD). Building on our previous observations that semaphorin 3F (Sema3f) is expressed in the outer retina and demonstrates anti ...
Ye Sun +17 more
doaj +1 more source
Investigative Ophthalmology and Visual Science, 2021 Pathologic myopia is a major cause of visual impairment worldwide. Pathologic myopia is distinctly different from high myopia. High myopia is a high degree of myopic refractive error, whereas pathologic myopia is defined by a presence of typical ...
K. Ohno-Matsui +10 more
semanticscholar +1 more source
Angiogenesis in squamous precancerous cervical lesions [PDF]
Vojnosanitetski Pregled, 2007 Background/Aim. Vascularisation is one of basic tumor's characteristics. Neoangiogenesis starts at the stage of the dysplastic epithelial changes, thus before the progression into invasive lesion. This study was designed to determine the relation between
Panjković Milan +1 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance The contribution of oxidative stress to the development of advanced age-related macular degeneration (AMD) is not fully understood. Here, we demonstrate that oxidative stress and hypoxia synergistically promote the accumulation of hypoxia ...
Savalan Babapoor-Farrokhran +15 more
semanticscholar +1 more source
Lipid Mediators, M2 Macrophages, and Pathological Neovascularization [PDF]
Trends in Molecular Medicine, 2018 Sasaki and colleagues [1] (JCI Insight 2018;3,e96902) identified the leukocyte inflammatory lipid mediator leukotriene B4 (LTB4)/LTB4 receptor 1 receptor-signaling axis in M2 macrophages as a causal pathway for the vascular endothelial growth factor-dependent pathological neovascularization in a mouse model that mimics wet age-related macular ...
Timothy Hla, Steven L. Swendeman
openaire +3 more sources
Significance of microvessel density in prostate cancer core biopsy [PDF]
Vojnosanitetski Pregled, 2015 Background/Aim. In prostate tumors, angiogenesis, measured as microvessel density, is associated with tumor stage and Gleason score. The aim of this study was determine neovascularization of prostatic adenocarcinomas in core biopsies and ...
Salapura-Dugonjić Aleksandra +3 more
doaj +1 more source
Scientific Reports, 2018 Diabetic retinopathy (DR) is a retinal microvascular disease characterized by inflammatory and angiogenic pathways. In this study, we evaluated NLRP3 inflammasome in a double transgenic mouse model, Akimba (Ins2AkitaxVEGF+/−), which demonstrates ...
S. S. Chaurasia +12 more
semanticscholar +1 more source
International Journal of Ophthalmology, 2013 Choroidal neovascularization (CNV) is an uncommon complication associated with a macular hole. In this case report of a rare condition, we present a pathologic myopia patient with a co-existent macular hole and choroidal neovascular membrane. The patient
Zhi-Qing Chen +4 more
doaj +1 more source
El cáncer en la función mitocondrial
Revista de la Facultad de Medicina, 2018 Metabolism alterations are associated with the loss of mitochondrial function in tumor cells. Current research discuss whether such loss is evident in function itself, or if cells can provide maximum stability to its functions. More studies are needed to
Sofía Isabel Freyre-Bernal +4 more
doaj +1 more source