Results 41 to 50 of about 1,067,090 (283)

Oxidative and Nitrosative Stress in Age-Related Macular Degeneration: A Review of Their Role in Different Stages of Disease

Antioxidants, 2021
Although the exact pathogenetic mechanisms leading to age-related macular degeneration (AMD) have not been clearly identified, oxidative damage in the retina and choroid due to an imbalance between local oxidants/anti-oxidant systems leading to chronic ...
Caterina Toma, Stefano De Cillà, Aurelio Palumbo, Divya Praveen Garhwal, Elena Grossini   +4 more
doaj   +1 more source

Apatinib, an Inhibitor of Vascular Endothelial Growth Factor Receptor 2, Suppresses Pathologic Ocular Neovascularization in Mice.

Investigative Ophthalmology and Visual Science, 2017
Purpose Vascular endothelial growth factor (VEGF) signaling via VEGF receptor 2 (VEGFR2) plays a crucial role in pathologic ocular neovascularization.
Koung Li Kim, W. Suh
semanticscholar   +1 more source

Inhibition of pathologic retinal neovascularization by  -defensins

Blood, 2005
Proliferative retinopathies, such as those complicating prematurity and diabetes, are major causes of blindness. A prominent feature of these retinopathies is excessive neovascularization, which is orchestrated by the hypoxia-induced vascular endothelial growth factor (VEGF) stimulating endothelial cells and the integrin-mediated adhesive interactions ...
Klaus T. Preissner, Yasmina Bdeir, Matina Economopoulou, Hans-Peter Hammes, Khalil Bdeir, Wuyuan Lu, Franz Fogt, Douglas B. Cines, Jacek Lubkowski, Triantafyllos Chavakis   +9 more
openaire   +4 more sources

VISUAL ACUITY OUTCOMES OF RANIBIZUMAB TREATMENT IN PATHOLOGIC MYOPIC EYES WITH MACULAR RETINOSCHISIS AND CHOROIDAL NEOVASCULARIZATION

Retina, 2017
Purpose: To investigate visual and morphological outcome in eyes with MRS and choroidal neovascularization (CNV) secondary to pathologic myopia treated with intravitreal (IVT) ranibizumab.
Lala Ceklic, M. Munk, U. Wolf-Schnurrbusch, M. Gekkieva, S. Wolf   +4 more
semanticscholar   +1 more source

Angiofluorographic Characteristics of Choroidal Neovascularization associated with Pathologic Myopia

romanian journal of ophthalmology, 2020
Purpose: To evaluate the incidence of choroidal neovascularization (CNV) in high myopic patients who experienced recent visual loss and to describe the characteristics of CNV that develop as a complication of pathologic myopia and were detected by fluorescein angiography (FA).
Irina Stefan, Anca Tomi
openaire   +3 more sources

Histological changes secondary to use of anti-angiogenic therapy after interruption of vasa vasorum flow in the descending aorta: results in a porcine model

Jornal Vascular Brasileiro, 2019
Background Anti-angiogenic regulators may have therapeutic implications for onset and progression of atherosclerosis. Objectives To demonstrate histological changes secondary to the use of bevacizumab in the aorta of pigs after interruption of flow in ...
Cyro Castro Júnior, Adamastor Humberto Pereira   +1 more
doaj   +1 more source

Key Multimodal Fundus Imaging Findings to Recognize Multifocal Choroiditis in Patients With Pathological Myopia

Frontiers in Medicine, 2022
Myopia represents a major socioeconomic burden with an increasing prevalence worldwide. Pathologic myopia refers to myopic patients with structural changes in the posterior pole including different patterns of chorioretinal atrophy, choroidal ...
Roberto Gallego-Pinazo, Sara Hernández, Rosa Dolz-Marco   +2 more
doaj   +1 more source

Thymidine phosphorylase and its possible correlation with the lung cancer phenotype features

Patologìâ, 2015
The tumor phenotype investigation is necessary for lung cancer drug therapy optimization. For this purpose is perspective to use the biochemical markers of angiogenesis. Thymidine phosphorylase may be one of them. Aim. The aim of study was to evaluate
E. M. Bakurova, R. V. Buzina, R. B. Kondratiuk, Yu. K. Gulkov, I. V. Vasilenko, B. G. Borzenko   +5 more
doaj   +1 more source

Predictors of pathologic stage in prostatic carcinoma. The role of neovascularity [PDF]

Cancer, 1994
Prostate adenocarcinoma is a significant cause of morbidity and mortality in older men. However, the histologic prevalence far exceeds clinically manifest disease. Increased screening has resulted in the detection of a large number of carcinomas of unknown malignant potential.
Steven D. Preston, Michael K. Brawer, Steven A. Bigler, Marianne Brown, Robert E. Deering   +4 more
openaire   +3 more sources

Intravitreal conbercept for choroidal neovascularisation secondary to pathological myopia in a real‐world setting in China

BMC Ophthalmology, 2021
Background To evaluate the 12-month efficacy and safety of intravitreal conbercept for myopic choroidal neovascularization (CNV). Methods A retrospective, observational study.
Xin Nie, Yulong Wang, Hong Yi, Yanbin Qiao   +3 more
doaj   +1 more source