Results 41 to 50 of about 34,514 (311)

Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization [PDF]

Journal of Biological Chemistry, 2020
Angiogenesis-mediated neovascularization in the eye is usually associated with visual complications. Pathological angiogenesis is particularly prominent in the retina in the settings of proliferative diabetic retinopathy, in which it can lead to permanent loss of vision.
David Gau, Lucile Vignaud, Abigail Allen, Zhijian Guo, Jose Sahel, David Boone, David Koes, Xavier Guillonneau, Partha Roy   +8 more
openaire   +2 more sources

FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice

Cell Reports, 2017
Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration.
Zhongjie Fu, Yan Gong, Raffael Liegl, Zhongxiao Wang, Chi-Hsiu Liu, Steven S. Meng, Samuel B. Burnim, Nicholas J. Saba, Thomas W. Fredrick, Peyton C. Morss, Ann Hellstrom, Saswata Talukdar, Lois E.H. Smith   +12 more
doaj   +1 more source

Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration [PDF]

, 2015
Treatment of the neovascular form of age-related macular degeneration (AMD) has been revolutionized by the introduction of such agents as ranibizumab, bevacizumab, and aflibercept.
Agrawal, Rupesh, De Salvo, Gabriella, Goverdhan, Srini, Keane, Pearse A., Sim, Dawn A., Tufail, Adnan   +5 more
core   +2 more sources

Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization Secondary to Endogenous Endophthalmitis

Kaohsiung Journal of Medical Sciences, 2009
Choroidal neovascularization is a major cause of visual loss in age-related macular degeneration. It is also a potential vision-threatening complication of pathologic myopia, uveitis, traumatic choroidal rupture and, rarely, endophthalmitis.
Shwu-Jiuan Sheu
doaj   +1 more source

Myeloid cell modulation by a GLP-1 receptor agonist regulates retinal angiogenesis in ischemic retinopathy

JCI Insight, 2021
Ischemic retinopathies including diabetic retinopathy are major causes of blindness. Although neurons and Müller glia are recognized as important regulators of reparative and pathologic angiogenesis, the role of mononuclear phagocytes (MPs ...
Lingli Zhou, Zhenhua Xu, Yumin Oh, Rico Gamuyao, Grace Lee, Yangyiran Xie, Hongkwan Cho, Seulki Lee, Elia J. Duh   +8 more
doaj   +1 more source

Significance of transvaginal Doppler ultrasonography for detection of malignant gestational trophoblastic disease [PDF]

Vojnosanitetski Pregled, 2005
Transvaginal Doppler ultrasonography has an important role in detecting and confirming the gestational trophoblastic disease (GTD). It can also be helpful in early detection of the malignant cases of GTD such as the invasion and protrusion of ...
Nikolić Branka, Rakić Snežana, Pavlović Dejan, Popovac Svetlana, Lukić Relja   +4 more
doaj   +1 more source

Overexpression of MMPs in Corneas Requiring Penetrating and Deep Anterior Lamellar Keratoplasty. [PDF]

, 2019
PurposeMatrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases involved in wound healing processes, including neovascularization and fibrosis. We assessed MMP protein expression levels in diseased corneas of patients requiring
Chan, Matilda F, Clay, Selene M, Hwang, David G, Oldenburg, Catherine E, Rose-Nussbaumer, Jennifer, Wolf, Marie   +5 more
core  

Optical coherence tomography to monitor photodynamic therapy in pathological myopia [PDF]

, 2006
To evaluate the role of optical coherence tomography (OCT) in determining choroidal neovascularisation (CNV) activity before and after photodynamic therapy (PDT) in patients with pathological myopia. METHODS: 33 patients (33 eyes) with
Garcia-Layana, A. (Alfredo), Salinas-Alaman, A. (Ángel), Maldonado, M.J. (Miguel J.), Sainz-Gomez, C. (C.), Fernandez-Hortelano, A. (A.)   +4 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Anti-Vascular Endothelial Growth Factor (Bevacizumab) Therapy Reduces Hypertrophic Scar Formation in a Rabbit Ear Wounding Model

Archives of Plastic Surgery, 2016
Background Hypertrophic scarring is a pathological condition that occurs after trauma or surgery. Angiogenesis occurs more often with hypertrophic scarring than with normotrophic scarring.
Do Hoon Kwak, Tae Hui Bae, Woo Seob Kim, Han Koo Kim   +3 more
doaj   +1 more source