Adipocytes in Aortic Stenosis: Association With Clinical and Morphological Indices
ABSTRACT Recently, great attention has been given to understanding the new pathogenetic mechanisms underlying aortic stenosis (AS). The study aims to understand the role of mature adipocytes in AS and their association with histologic, clinical, and echocardiographic data, an area previously overlooked in AS research.
Elena Zoico +9 more
wiley +1 more source
Pericyte Expression of VEGF-A Minimally Impacts Ocular Vascular Development and Neovascularization. [PDF]
Song YS +5 more
europepmc +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
AI‐assisted design of a VEGFR2 agonistic peptide that promotes angiogenesis and wound repair
Abstract Vascular endothelial growth factor (VEGF) serves as a principal regulator of neovascularization and is essential for vascular regeneration. In this study, we identified and evaluated VEGF Mimetic Peptide3 (VMP3), a novel synthetic peptide developed as a potential VEGFR‐2/VEGF‐A modulator.
Farzana Yasmeen +7 more
wiley +1 more source
Interleukin 10 enhances endothelial progenitor cell-mediated angiogenesis in extrahepatic portal venous obstruction. [PDF]
Zhang JS.
europepmc +1 more source
Hydrogen‐Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy
The combination of VSD and hydrogen‐rich saline is used to treat diabetic foot ulcers. In vitro and in vivo studies reveal that hydrogen‐enrich hyaluronic acid dressings enhance skin fibroblast repair ability by regulating mitophagy via the SIRT3 and its downstream signaling pathways, ultimately accelerating wound healing in diabetic foot ulcers ...
Ziyu Xu +8 more
wiley +1 more source
Fracture healing potential of tetracalcium phosphate: An experimental study in a rat femur standardized diaphyseal osteotomy with open approach. [PDF]
Karabak B +6 more
europepmc +1 more source
Single‐cell transcriptomics reveals that the human retina expresses a broad repertoire of steroid hormone biosynthesis and estrogen signalling genes. Functional validation in retinal explants shows that local estrogen synthesis is neuroprotective, preventing photoreceptor death and limiting microglial activation. Abstract Steroid hormones, particularly
Antolin Canto +6 more
wiley +1 more source
Bioinspired Provisional Matrix Stimulates Regenerative Healing of Diabetic Wounds. [PDF]
Short WD +11 more
europepmc +1 more source

