Results 141 to 150 of about 225,756 (386)

Minimizing projection artifacts for accurate presentation of choroidal neovascularization in OCT micro-angiography.

Biomedical Optics Express, 2015
Current optical coherence tomography (OCT) based micro-angiography is prone to a projection (or tailing) effect due to the high scattering property of blood within overlying patent vessels, creating artifacts that interfere with the interpretation of ...
Anqi Zhang, Qinqin Zhang, Ruikang K. Wang   +2 more
semanticscholar   +1 more source

Neovascularization in Ewing’s sarcoma

Neoplasma, 2018
Ewing's sarcoma is the second most common bone malignancy in adolescents and young adults after osteosarcoma. Similar to other solid tumors, Ewing's sarcomas require an adequate vascular supply to grow and survive. The development and maintenance of vascular supply is accomplished via three main mechanisms; angiogenesis, vasculogenesis, and tumor cell ...
Panayiotis D. Megaloikonomos, Stamatios Theocharis, Christos Vottis, Andreas F. Mavrogenis, George Agrogiannis   +4 more
openaire   +3 more sources

Responsive ROS‐Augmented Prodrug Hybridization Nanoassemblies for Multidimensionally Synergitic Treatment of Hepatocellular Carcinoma in Cascade Assaults

Advanced Science, EarlyView.
This study proposes a novel HCC therapy using CA‐4S2@ES‐Cu nanomedicines to amplify cuproptosis, enhancing chemotherapy and immunotherapy. CA‐4 and ES‐Cu synergistically inhibit tumor growth, induce immune responses, and reverse the immunosuppressive microenvironment, offering an effective multidimensional therapeutic strategy for HCC treatment ...
Yingjie Zeng, Yuening Cao, Senmiao Ren, Chaozheng Zhang, Jianan Liu, Ke Liu, Yan Wang, Hongyu Chen, Fengjiao Zhou, Xiuli Yang, Xian Ge, Tingting Zhang, Tianbao Wang, Yao He, Defang Li, Chuantao Zhang, Jun Lu   +16 more
wiley   +1 more source

Enhanced Integrin α4β1-Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes. [PDF]

, 2016
Diabetes is associated with a deficit of circulating endothelial progenitor cells (EPCs), which has been attributed to their defective mobilization from the bone marrow.
Abplanalp, Wesley T, Bhatnagar, Aruni, Cantor, Joseph M, Conklin, Daniel J, Ginsberg, Mark H, O'Toole, Timothy E, Wysoczynski, Marcin   +6 more
core   +2 more sources

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

Understanding Learned Models by Identifying Important Features at the Right Resolution

, 2018
In many application domains, it is important to characterize how complex learned models make their decisions across the distribution of instances. One way to do this is to identify the features and interactions among them that contribute to a model's ...
Craven, Mark, Lee, Kyubin, Sood, Akshay
core   +1 more source

Multidimensional en-face OCT imaging of the retina. [PDF]

, 2009
Fast T-scanning (transverse scanning, en-face) was used to build B-scan or C-scan optical coherence tomography (OCT) images of the retina. Several unique signature patterns of en-face (coronal) are reviewed in conjunction with associated confocal images ...
Adrian G. Podoleanu, Cucu, de Boer, George M. Dobre, Gh, Gh, Gh, Gh, Gh, Gh, Gh, Gh, Hitzenberger, Hong, Huber, Jiao, John Rogers, Justin Pedro, Leitgeb, Lim, Mark Hathaway, Masters, Merino, Patricia Garcia, Philippe Laissue, Pircher, Pircher, Pircher, Pircher, Richard B. Rosen, Rosa, Tuohy, Van Velthoven, Wojtkowski, Yasuno   +34 more
core   +1 more source

Bispecific Antibody Targeting VEGF/TGF‐β Synergizes with Local Radiotherapy: Turning Tumors from Cold to Inflamed and Amplifying Abscopal Effects

Advanced Science, EarlyView.
Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu, Ming Yi, Ji Chen, Jing Zhang, Xiaobin Ma, Xiaojun Zhang, Liang Zeng, Yan Xue, Haimei Wen, Yujiao Deng, Pengfei Zhou, Kongming Wu, Huafeng Kang, Zhijun Dai   +13 more
wiley   +1 more source

Adverse events associated with intraocular injection of anti-VEGF(bevacizumab) in retinal vein ccclusion: a case report [PDF]

, 2015
Introduction: Antiangiogenic agents are often administered for treatment of Branch Retinal Vein Occlusion (BRVO). Among them, Bevacizumab has noticeable antiangiogenic and antiedemigenic properties and possesses great capacity to penetrate the retinal ...
ARTICO, Marco, BOTTONE, Andrea, Domenica Piraino, Carmen, Mollicone, Antonella, PACELLA, Elena, PACELLA, FERNANDA, Romana Parisiella, Francesca, TURCHETTI, PAOLO   +7 more
core   +1 more source

Neovascularization of the Disc in Chronic Simple Glaucoma [PDF]

, 1954
Mandabi Sengupta
openalex   +1 more source