Results 141 to 150 of about 1,206 (172)

Piezo, Nephrocyte Function, and Slit Diaphragm Maintenance in Drosophila

Journal of the American Society of Nephrology
Visual Abstract Key Points Piezo channels, known for detecting mechanical pressure, were found to be expressed at the lacuna channel membranes of nephrocytes.
Yunpo Zhao, Jianli Duan, Iden D. Han, Joyce van de Leemput, Patricio E. Ray, Z. Han   +5 more
semanticscholar   +3 more sources

A Drug-Screening Platform for Podocytopathies in Drosophila Nephrocytes.

Journal of the American Society of Nephrology
BACKGROUND The complex cellular architecture of the glomerular filtration barrier is not recapitulated in vitro, representing a major obstacle for drug screening.
Dominik Spitz, Jost Wiggering, Chiranth Prakash, Maximilian H Ulbrich, Ronen Schneider, Tobias Hermle   +5 more
semanticscholar   +3 more sources

The Drosophila nephrocyte

Current Opinion in Nephrology and Hypertension, 2011
The functioning kidney requires proper organization in multiple cell types that mediate filtration and removal of wastes. Interest has increasingly focused on the podocyte as an important mediator of kidney function; defects in podocyte function likely mediate a broad palate of kidney dysfunctions.
R. Cagan
semanticscholar   +3 more sources

HIV-1 Protein Nef Acts in Synergy with APOL1-G1 to Impair Nephrocyte Function by Inhibiting Autophagy and Endocytosis Pathway

Journal of the American Society of Nephrology, 2023
IFN ...
Jun-Yi Zhu
semanticscholar   +1 more source

Drosophila Filamin Exhibits a Mechanoprotective Role During Nephrocyte Injury via Hypertrophy

Journal of the American Society of Nephrology, 2021
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Sybille Koehler, Barry Denholm
semanticscholar   +1 more source

Using Drosophila nephrocytes in genetic kidney disease

Cell and Tissue Research, 2017
Renal diseases are a growing health burden, and innovative models to study their pathomechanisms are greatly needed. Here, we highlight how the fruit fly Drosophila melanogaster can be used to model kidney diseases. We focus on the nephrocyte that has recently been shown to exhibit podocyte and proximal tubular cell features.
Martin, Helmstädter, Matias, Simons
openaire   +2 more sources

Impact of cypermethrin in nephrocytes of freshwater fish Catla catla

Environmental Toxicology and Pharmacology, 2021
The kidney of Catla catla, chronically exposed to sub-lethal concentrations (0.24 μg/L and 0.41 μg/L) of cypermethrin revealed a significant elevation in the activity of antioxidants superoxide dismutase (SOD), catalase (CAT), glutathione-s-transferase (GST) and reduced glutathione (GSH) after 15 days, followed by a decline of up to 45 days.
Sharma, Ritu, Jindal, Rajinder, Faggio, Caterina   +2 more
openaire   +2 more sources

Location, morphology and function of nephrocytes in termites

Arthropod Structure & Development, 2015
Insect nephrocytes are cells bathed in hemolymph and considered to have an excretory function. These cells have ambiguous nomenclature and are understudied in termites. This study is the first report on the occurrence, morphology and function of nephrocytes in different termite castes.
Ana Maria Costa-Leonardo, Vanelize Janei, Lara Teixeira Laranjo, Ives Haifig   +3 more
openaire   +3 more sources

Functional Role of the Mechanosensitive Channel Piezo for Nephrocyte Biology

Journal of the American Society of Nephrology
Karl K. Alornyo, Paris Hazelton-Cavill, Kristina Schulz, Ilka Edenhofer, Maja Lindenmeyer, Christian Lohr, Tobias B. Huber, Barry Denholm, Sybille Koehler   +8 more
semanticscholar   +2 more sources

Nephrocytes of harvestmen, Leiobunum limbatum and L. rotundum

Tissue and Cell, 1991
Nephrocytes are said to be able to take up substances from the hemolymph. In Opiliones, which were examined electron microscopically three different types of nephrocytes were found. Numerous large nephrocytes lie clustered between the muscles in the anterior region of the body.
K, Zanger, D R, Dannhorn, K A, Seitz, W, Peters   +3 more
openaire   +2 more sources