Results 71 to 80 of about 53,664 (239)
Crystallization and Stone Formation Inside the Nephron [PDF]
, 1996 A model is presented visualizing the events leading to calcium-salt, crystal- and stone-formation inside the nephron. For each nephron segment, handling of urine components relevant to stone formation is considered and urine composition determined.
Kok, Dirk J.
core +1 more source
Relationship among nephron number, cortical volume, and glomerular pressure in healthy kidney donors
Physiological ReportsGlomerular hypertension is a critical factor in kidney disease progression. Traditionally, nephron number (Nglom) was considered a determinant of glomerular hemodynamics, but emerging evidence suggests a more substantial impact of renal structural ...
Hiroki Nobayashi +10 more
doaj +1 more source
Biology, 2018 One of the significant organ systems which decline in aging is the kidney. While the causes of age-associated decline in renal function are likely multifactorial, oxidative stress and inflammation are hypothesized to play important roles in the ...
Kiran S. Panickar, Dennis E. Jewell
doaj +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
Medicinal Research Reviews, EarlyView.ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Mapping the Knowledge Structure and Thematic Trends of Wilms Tumor: Insights From Text Mining
Organ Medicine, EarlyView.This scientometric analysis of Wilms tumor research from 1945 to 2024 highlights United States research leadership, limited international collaboration, and emerging hotspots in biomarkers, nephron‐sparing surgery, and immunotherapy. ABSTRACT Background Wilms tumor (WT), also known as nephroblastoma, is one of the most common renal malignancies in ...
Boshen Shu +4 more
wiley +1 more source
, 2017 Notch signaling plays important roles during mammalian nephrogenesis. To investigate if Notch regulates nephron segmentation, we performed Notch loss-of-function and gain-of-function studies in developing nephrons in mice. Contrary to the previous notion
Eunah Chung +2 more
core +1 more source
Precision Medical Sciences, EarlyView.Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Epidemiological studies have demonstrated a link between chronic kidney disease (CKD) and environmental mercury (Hg) exposure. Colombia has a well‐documented history of artisanal and small‐scale gold mining, where Hg exposure affects miners and nearby riverside and urban populations. This study aimed to evaluate the effects of polymorphisms in
Diana M. Narváez +16 more
wiley +1 more source
Autoradiography of the Isolated Nephron.
Experimental Biology and Medicine, 1959 SummaryA method is described in which the combination of microdissection and a stripping film technic has provided autoradiograms of the isolated nephron. Accurate localization of site of action of suitable tagged materials was obtained. For example, after injection of C14 Vit.
E M, DARMADY, F, STRANACK
openaire +2 more sources
Rationale for inquiries into the tradeoff-in-the-nephron hypothesis.
, 2022 Rationale for inquiries into the tradeoff-in-the-nephron hypothesis.
Darren E. Gemoets (13184242) +2 more
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