Results 101 to 110 of about 367,294 (339)
Differential renal effects of candesartan at high-and ultra-high doses in diabetic mice: potential role of ACE2/AT2R/Mas [PDF]
, 2016 High doses of Ang II receptor (AT1R) blockers (ARBs) are renoprotective in diabetes. Underlying mechanisms remain unclear. We evaluated whether high/ultra-high doses of candesartan (ARB) up-regulate angiotensin-converting enzyme 2 (ACE2)/Ang II type 2 ...
Antunes, Tayze +10 more
core +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley +1 more source
Circ-0069561 as a novel diagnostic biomarker for progression of diabetic kidney disease
Renal FailureBackground Circular RNAs (circRNAs) are non-coding RNAs that are key regulators of the initiation and progression of various human diseases. However, the role of circRNAs in diabetic kidney disease (DKD) remains unknown.Methods Whole high-throughput RNA ...
Chaoyi Chen +7 more
doaj +1 more source
Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship [PDF]
, 2018 Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated.
Agüero, Rocio +4 more
core
5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng +14 more
wiley +1 more source
Drug Design, Development and TherapyYijing Zhou,* Chengli Lou,* Xiuqin Xu, Bo Feng, Xiaoping Fan, Xiangjing Wang Department of Nephropathy, Jiaxing Traditional Chinese Medicine Hospital, Jiaxing, People’s Republic of China*These authors contributed equally to this ...
Zhou Y +5 more
doaj
Scientific ReportsRituximab occasionally induces reactivation of hepatitis C virus (HCV) in patients with resolved HCV infection, sometimes with fatal consequences. As rituximab has become one of the first-line therapies for the treatment of phospholipase A2 receptor ...
Xiaodan Li +7 more
doaj +1 more source
Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids and its modification by Stearoyl-CoA desaturases and cyclic AMP [PDF]
, 2011 Podocyte apoptosis is a hallmark in the development and progression of diabetic nephropathy (DN). Several factors of the diabetic milieu are known to induce podocyte apoptosis. Currently, the role of free fatty acids (FFAs) for podocytopathy and podocyte
Sieber, Jonas
core +1 more source