Results 21 to 30 of about 481,070 (386)

Correlation between gut microbiome and cognitive impairment in patients undergoing peritoneal dialysis

BMC Nephrology, 2023
Background Growing evidence has demonstrated that patients undergoing peritoneal dialysis (PD) are more likely to experience cognitive impairment than patients with non-dialysis end-stage renal disease (ESRD); however, the underlying mechanisms remain ...
Jingjing Wang, Siyang Wu, Jin Zhang, Yuanyuan Li, Yonggui Wu, Xiangming Qi   +5 more
doaj   +1 more source

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.

New England Journal of Medicine, 2019
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT2), exploratory results have ...
V. Perkovic, M. Jardine, B. Neal, Severine Bompoint, H. Heerspink, D. Charytan, Robert Edwards, R. Agarwal, G. Bakris, S. Bull, C. Cannon, G. Capuano, P. Chu, D. de Zeeuw, T. Greene, A. Levin, C. Pollock, D. Wheeler, Yshai Yavin, Hong Zhang, B. Zinman, G. Meininger, B. Brenner, K. Mahaffey   +23 more
semanticscholar   +1 more source

Noninvasive Urinary Monitoring of Progression in IgA Nephropathy. [PDF]

, 2019
Standard methods for detecting and monitoring of IgA nephropathy (IgAN) have conventionally required kidney biopsies or suffer from poor sensitivity and specificity.
Fervenza, Fernando C, Lafayette, Richard A, Sarwal, Minnie M, Sarwal, Reuben D, Yang, Joshua YC   +4 more
core   +1 more source

Association between thyroid hormones and diabetic kidney disease in Chinese adults

BMC Endocrine Disorders, 2023
Objective We aimed to explore the association between thyroid hormones and different stages of diabetic kidney disease (DKD) in Chinese adults. Methods This is a retrospective study involving 2,832 participants. DKD was diagnosed and classified according
Meng-chao Liu, Jia-lin Li, Yue-fen Wang, Yuan Meng, Zhen Cai, Cun Shen, Meng-di Wang, Wen-jing Zhao, Wen-quan Niu   +8 more
doaj   +1 more source

Normal-weight central obesity: implications for diabetes mellitus

Frontiers in Nutrition, 2023
BackgroundCurrent guidelines for obesity prevention and control focus on body mass index (BMI) and rarely address central obesity. Few studies have been conducted on the association between normal-weight central obesity and the risk of diabetes mellitus (
Xueshan Jin, Jiajun Liu, Qiuyu Cao, Jiehua Lin, Guangfu Wu, Longhui Liu, Shan Jiang, Xin Zhou, Zhiqiang Li, Aicheng Yang   +9 more
doaj   +1 more source

Vogt-Koyanagi-Harada Syndrome in Two Patients with Immunoglobulin A Nephropathy [PDF]

, 2007
We describe herein 2 patients who developed Vogt-Koyanagi-Harada syndrome in the course of renal biopsy-proven immunoglobulin A (IgA) nephropathy. A 61-year-old man with an 11-year history of IgA nephropathy and a 16-year history of thyroiditis, and a 56-
Masuda, Ikuya, Matsuo, Toshihiko, Nose, Soichiro, Ota, Kosuke, Sunami, Reiko, Yamadori, Ichiro   +5 more
core   +1 more source

Hyperglycemia and Hyperlipidemia Act Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB Mice [PDF]

, 2004
Diabetic nephropathy is the leading cause of end-stage renal disease in Western countries, but only a portion of diabetic patients develop diabetic nephropathy.
Alpers, Charles E., Hudkins, Kelly L., Kirk, Elizabeth, LeBoeuf, Renée C., Mühlfeld, Anja S., Segerer, Stephan, Spencer, Min W.   +6 more
core   +1 more source

Human umbilical cord mesenchymal stem cells reduce oxidative damage and apoptosis in diabetic nephropathy by activating Nrf2

Stem Cell Research & Therapy, 2021
Background Mesenchymal stem cells (MSCs) have a therapeutic effect on diabetic nephropathy (DN) but the underlying mechanism remains unclear. This study was conducted to investigate whether human umbilical cord-MSCs (hUCMSCs) can induce oxidative damage ...
Ping Nie, Xue Bai, Yan Lou, Yuexin Zhu, Shan Jiang, Lina Zhang, Na Tian, Ping Luo, Bing Li   +8 more
doaj   +1 more source

Urinary MicroRNA Profiling in the Nephropathy of Type 1 Diabetes [PDF]

, 2013
Background: Patients with Type 1 Diabetes (T1D) are particularly vulnerable to development of Diabetic nephropathy (DN) leading to End Stage Renal Disease.
A Krupa, A Micera, Analysis The Case for Objective Bayesian, AO Phillips, B John, Christos Argyropoulos, D Lunn, D Macconi, D Shan, David Galas, David Huang, Demetrius Ellis, DP Bartel, G Ghosh, G Togliatto, G Wang, G Wang, G Wang, H Guo, H Haller, H Sun, J Hou, JA Weber, JM Lorenzen, John Johnson, Jose Bernardo, K Bhatt, K Heese, K Sharma, Kai Wang, Karin Jandeleit-Dahm, L Denby, L Held, L Mahimainathan, L Matthews, M Ashburner, M Hackl, M Kato, M Kato, M Kato, ME Molitch, MW Pfaffl, O García-Sánchez, P Dentelli, P Kantharidis, P Ruggenenti, PE Pergola, R Bonofiglio, R Liao, RC Friedman, RC Gentleman, RC Lee, RW Carthew, S Fatima, Sara McClarty, SM Titan, SW Shan, T Roweis, Sam, TD Schmittgen, Trevor Orchard, U Tran, VA Valera, W Stacklies, X Wang, X-Y Bai, Y Dai, YS Kanwar, Z Chun-Zhi   +67 more
core   +3 more sources

The emerging role of cellular senescence in renal diseases [PDF]

, 2020
Cellular senescence represents the state of irreversible cell cycle arrest during cell division. Cellular senescence not only plays a role in diverse biological events such as embryogenesis, tissue regeneration and repair, ageing and tumour occurrence ...
Alpini, Gianfranco, Chen, Rong, Francis, Heather, Glaser, Shannon, Li, Siwen, Li, Xuesen, Meng, Fanyin, Wan, Ying, Wu, Nan, Zhang, Chunmei, Zhou, Bingru, Zhou, Tianhao, Zou, Ping   +12 more
core   +1 more source