Results 31 to 40 of about 178,215 (170)

miR-374a Regulates Inflammatory Response in Diabetic Nephropathy by Targeting MCP-1 Expression

Frontiers in Pharmacology, 2018
The microRNA (mir)-374a has been implicated in several types of human cancer; however, its role in diabetic nephropathy (DN) remains unclear. Monocyte chemoattractant protein (MCP)-1 is a chemokine that recruits macrophages to inflammatory sites and is ...
Zijun Yang, Zuishuang Guo, Ji Dong, Shifeng Sheng, Yulin Wang, Lu Yu, Hongru Wang, Lin Tang   +7 more
doaj   +1 more source

Regulation of the autophagy plays an important role in acute kidney injury induced acute lung injury

Renal Failure, 2022
Aim This study aimed to investigate the regulatory role of autophagy in acute kidney injury (AKI) induced acute lung injury (ALI).Methods The male Sprague–Dawley rats were divided into four groups: normal saline-treated sham rats (sham group), normal ...
Ruolin Wang, Siheng Shen, Luyong Jian, Shuhua Liu, Qi Yuan, Huahui Guo, Jiasheng Huang, Penghui Chen, Renfa Huang   +8 more
doaj   +1 more source

Shenlian Decoction Ameliorates LPS-Related Inflammation in db/db Mice: Coupling Network Pharmacology With Experimental Verification

Journal of Diabetes Research
Conclusions: This research investigated the multigene pharmacological mechanism of SL decoction against T2DM using network pharmacology and in vivo experiments.
Yi-fan Liu, Yuan-yuan Liu, Yao Xiao, Wei-jun Huang, Rui-xi Sun, Jie Hu, Xiao-zhe Fu, Chu-xiao Tian, Qiang Fu, Jin-xi Zhao   +9 more
doaj   +1 more source

Incidence, risk factors and prognosis of acute kidney injury in patients treated with immune checkpoint inhibitors: a retrospective study

Scientific Reports, 2022
Immune checkpoint inhibitors (ICIs) change the prognosis of many cancer patients. With the increasing use of ICIs, immune-related adverse events are occurring, including acute kidney injury (AKI).
Ming-Su Ji, Rilige Wu, Zhe Feng, Yuan-Da Wang, Yong Wang, Li Zhang, Xue-Feng Sun, Xiang-Mei Chen, Kun-Lun He, Guang-Yan Cai   +9 more
doaj   +1 more source

Nomogram for thromboembolic events in primary membranous nephropathy associated with PLA2R antibody

Scientific Reports
Patients with nephrotic syndrome, particularly those with primary membranous nephropathy (pMN), are at a heightened risk of thromboembolic events.
Zihan Zhai, Yanhong Guo, Lu Yu, Yulin Wang, Liuwei Wang, Qiuhong Li, Yapei Yuan, Lin Tang   +7 more
doaj   +1 more source

Role of telitacicept in the treatment of IgA nephropathy

European Journal of Medical Research, 2023
IgA nephropathy (IgAN) is the most common primary glomerular disease in the world, and up to 40% of patients with IgAN develop end-stage renal disease (ESRD). At present, an increasing amount of evidence indicates that the pathogenesis of IgAN is related
Lijun Wu, Xinru Du, Xuehong Lu
doaj   +1 more source

Identification of potential biomarkers associated with mitochondrial oxidative stress in idiopathic pulmonary arterial hypertension via bioinformatic and experimental analysis

Scientific Reports
Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and devastating disorder. Mitochondrial oxidative stress has been found to be involved in PAH development.
Yanting Zhu, Xiaoming Wang, Xiaohui Yan, Yan Sun, Qiong Wang, Cui Zhai   +5 more
doaj   +1 more source

A preliminary study of KAT2A on cGAS-related immunity in inflammation amplification of systemic lupus erythematosus

Cell Death and Disease, 2021
Previous studies demonstrated that cGAS pathway is related to the inflammation amplification in a variety of autoimmune diseases. Lysine acetyltransferase family (KATs) can regulate the nuclear transcription or cytoplasmic activation of cGAS through ...
Youzhou Tang, Xinyu Li, Yafang Wei, Yongchao Sun, Yeyi Yang, Xianming Zhang, Zhihao Gao, Jishi Liu, Quan Zhuang   +8 more
doaj   +1 more source

Obstructive Nephropathy.

Internal Medicine, 2000
Obstructive nephropathy is a relatively common entity that is treatable and often reversible. It occurs at all ages from infancy to elderly subjects. Obstructive uropathy is classified according to the degree, duration and site of the obstruction. It is the result of functional or anatomic lesions located in the urinary tract. The causes of obstructive
openaire   +4 more sources

Diabetic Nephropathy [PDF]

Diabetes Care, 2005
Perspectives on the News commentaries are part of a free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, designates this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate.
openaire   +4 more sources