Results 11 to 20 of about 306,712 (215)

Noninvasive Urinary Monitoring of Progression in IgA Nephropathy. [PDF]

, 2019
Standard methods for detecting and monitoring of IgA nephropathy (IgAN) have conventionally required kidney biopsies or suffer from poor sensitivity and specificity.
Fervenza, Fernando C, Lafayette, Richard A, Sarwal, Minnie M, Sarwal, Reuben D, Yang, Joshua YC   +4 more
core   +1 more source

Correlation between gut microbiome and cognitive impairment in patients undergoing peritoneal dialysis

BMC Nephrology, 2023
Background Growing evidence has demonstrated that patients undergoing peritoneal dialysis (PD) are more likely to experience cognitive impairment than patients with non-dialysis end-stage renal disease (ESRD); however, the underlying mechanisms remain ...
Jingjing Wang, Siyang Wu, Jin Zhang, Yuanyuan Li, Yonggui Wu, Xiangming Qi   +5 more
doaj   +1 more source

Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance. [PDF]

, 2014
Oxidative stress has been proposed to be a unifying cause for diabetic nephropathy and a target for novel therapies. Here we apply a new endogenous reduction-oxidation (redox) sensor, hyperpolarized (HP) (13)C dehydroascorbate (DHA), in conjunction with ...
Bok, Robert, Jen, Kuang-Yu, Keshari, Kayvan R, Kurhanewicz, John, Larson, Peder, Sai, Victor, Van Criekinge, Mark, Wang, Zhen J, Wilson, David M   +8 more
core   +1 more source

Case Report: Pathogenic MYH9 c.5797delC Mutation in a Patient With Apparent Thrombocytopenia and Nephropathy

Frontiers in Genetics, 2021
MYH9-related disease or disorder (MYH9-RD) is an autosomal dominant disease caused by mutations in the MYH9 gene. Mutations in this gene initially affect the hemic system, and other manifestations may evolve with age.
Pingping Ren, Pingping Ren, Pingping Ren, Hongjun Chen, Hongjun Chen, Hongjun Chen, Yucheng Wang, Yucheng Wang, Yucheng Wang, Cuili Wang, Cuili Wang, Cuili Wang, Shi Feng, Shi Feng, Shi Feng, Hong Jiang, Hong Jiang, Hong Jiang, Jianghua Chen, Jianghua Chen, Jianghua Chen   +20 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

Membranous nephropathy

Brazilian Journal of Nephrology, 2023
ABSTRACT Membranous nephropathy is a glomerulopathy, which main affected target is the podocyte, and has consequences on the glomerular basement membrane. It is more common in adults, especially over 50 years of age. The clinical presentation is nephrotic syndrome, but many cases can evolve with asymptomatic non-nephrotic proteinuria.
Márcio Dantas, Lázaro Bruno Borges Silva, Barbhara Thaís Maciel Pontes, Marlene Antônia dos Reis, Patrícia Soares Nunes de Lima, Miguel Moysés Neto   +5 more
openaire   +5 more sources

Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA [PDF]

, 2010
Ochratoxin A (OTA) is a nephrotoxin and carcinogen that is associated with Balkan endemic nephropathy and urinary tract tumors. OTA crosses the placenta and causes adducts in the liver and kidney DNA of newborns.
Jamie E. Jennings-Gee, Mariana Tozlovanu, Richard Manderville, Mark Steven Miller, Annie Pfohl-Leszkowicz, Gary G. Schwartz, O’Brien, Pfohl-Leszkowicz, Reddy, Krogh, Stoev, Chernozemsky, Pfohl-Leszkowicz, Castegnaro, Huyghe, Schwartz, Ueta, Raymond, Mantle, Mantle, Pfohl-Leszkowicz, Petkova-Bocharova, Petkova-Bocharova, Satoh, Manderville, Faucet, Gillman, Molinié, Nguyen, Petkova-Bocharova, Faucet-Marquis, Frenette, Pfohl-Leszkowicz, Mantle, Pfohl-Leszkowicz, Pinelli, El Adlouni, Petkova-Bocharova, Pfohl-Leszkowicz, Verma, Kamataki, Gustafsson, Atanasova, Pfohl-Leszkowicz, Pfohl-Leszkowicz, Pfohl-Leszkowicz, Dimitrov, Møller, Bay, Bose, Solti, Patil, Lei   +52 more
core   +3 more sources

Association between thyroid hormones and diabetic kidney disease in Chinese adults

BMC Endocrine Disorders, 2023
Objective We aimed to explore the association between thyroid hormones and different stages of diabetic kidney disease (DKD) in Chinese adults. Methods This is a retrospective study involving 2,832 participants. DKD was diagnosed and classified according
Meng-chao Liu, Jia-lin Li, Yue-fen Wang, Yuan Meng, Zhen Cai, Cun Shen, Meng-di Wang, Wen-jing Zhao, Wen-quan Niu   +8 more
doaj   +1 more source

Normal-weight central obesity: implications for diabetes mellitus

Frontiers in Nutrition, 2023
BackgroundCurrent guidelines for obesity prevention and control focus on body mass index (BMI) and rarely address central obesity. Few studies have been conducted on the association between normal-weight central obesity and the risk of diabetes mellitus (
Xueshan Jin, Jiajun Liu, Qiuyu Cao, Jiehua Lin, Guangfu Wu, Longhui Liu, Shan Jiang, Xin Zhou, Zhiqiang Li, Aicheng Yang   +9 more
doaj   +1 more source

Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]

, 2017
IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna, Delles, Christian, Filip, Szymon, Gakiopoulou, Chara, Jankowski, Joachim, Krochmal, Magdalena, Markoska, Katerina, Mischak, Harald, Orange, Clare, Spasovski, Goce, Vlahou, Antonia, Zoidakis, Jerome   +11 more
core   +2 more sources