Results 21 to 30 of about 178,215 (170)

Preeclamptic nephropathy [PDF]

open access: yesNephrology, 2011
ABSTRACTWith the recent discovery of potential serum ‘toxins’ in human preeclampsia, it is timely to consider how these might relate to preeclamptic nephropathy. This review will discuss the clinical presentation of preeclampsia with an emphasis on renal involvement. It will explore the nature of the renal histological changes including endothelial and
Hennessy, Annemarie (R11780)   +1 more
openaire   +3 more sources

Critical Role of Cysteine-Rich Protein 61 in Mediating the Activation of Renal Fibroblasts

open access: yesFrontiers in Physiology, 2019
ObjectiveTo explore the expression of cysteine-rich protein 61 (Cyr61) in ischemic renal fibrosis and the role of Cyr61 in mediating the activation of renal fibroblasts.Methods(1) The rat model of renal fibrosis was established after ischemia-reperfusion
Hang Liu   +10 more
doaj   +1 more source

SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

open access: yesStem Cell Research & Therapy, 2020
Introduction Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis (PD). Combination therapies are emerging as a promising treatment for tissue damage.
Yanhong Guo   +6 more
doaj   +1 more source

Ameliorative role of SIRT1 in peritoneal fibrosis: an in vivo and in vitro study

open access: yesCell & Bioscience, 2021
Background Peritoneal fibrosis is one of the major complications induced by peritoneal dialysis (PD). Damaged integrity and function of peritoneum caused by peritoneal fibrosis not only limits the curative efficacy of PD and but affects the prognosis of ...
Yanhong Guo   +7 more
doaj   +1 more source

Hantavirus Nephropathy [PDF]

open access: yesJournal of the American Society of Nephrology, 2008
Pathogenic rodent-borne hantaviruses cause in humans generalized infections that involve the peripheral vascular bed and severely affect their permeability. We describe a 30-yr-old male patient with clinical symptoms characterizing five conventional phases of hemorrhagic fever with renal syndrome after an uncommonly severe hantavirus infection with the
Dusan, Ferluga, Alenka, Vizjak
openaire   +2 more sources

Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease

open access: yesFrontiers in Pharmacology, 2022
Necroptosis was elevated in both tubulointerstitial and glomerular renal tissue in patients with diabetic kidney disease (DKD), and was most pronounced on glomerulus in the stage with macroalbuminuria. This study further explored whether paeoniflorin (PF)
Xian Wang   +8 more
doaj   +1 more source

A Study on the Correlations of Anxiety and Depression With Self-Management Ability and Endogenous Creatinine Clearance Rate in Renal Transplant Recipients

open access: yesFrontiers in Psychiatry, 2021
Objective: To explore the effects of anxiety and depression on the self-management ability and endogenous creatinine clearance rate of renal transplant patients.Method: Eighty-eight renal transplant recipients who were followed up in the outpatient ...
ShiMin Hu   +7 more
doaj   +1 more source

Wogonin upregulates SOCS3 to alleviate the injury in Diabetic Nephropathy by inhibiting TLR4-mediated JAK/STAT/AIM2 signaling pathway

open access: yesMolecular Medicine
Background Diabetic nephropathy (DN) is a life-threatening renal disease and needs urgent therapies. Wogonin is renoprotective in DN. This study aimed to explore the mechanism of how wogonin regulated high glucose (HG)-induced renal cell injury.
Yufeng Liu   +5 more
doaj   +1 more source

Prognostic value of transthoracic echocardiography score for the prognosis of continuous ambulatory peritoneal dialysis patients

open access: yesBMC Nephrology
Background We devoted ourselves to proving that the initial transthoracic echocardiography score (TTES) had predictive significance for patients with continuous ambulatory peritoneal dialysis (CAPD).
Sheng Wan   +5 more
doaj   +1 more source

Association between change in serum uric acid and rapid decline in kidney function in China

open access: yesScientific Reports
While the elevation of serum uric acid (SUA) is acknowledged as a risk factor for chronic kidney disease, the independent extent to which variations in SUA levels are correlated with temporal changes in estimated glomerular filtration rate (eGFR) remains
Yu Li   +6 more
doaj   +1 more source

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