Results 21 to 30 of about 306,712 (215)
Stem Cell Research & Therapy, 2021 Background Mesenchymal stem cells (MSCs) have a therapeutic effect on diabetic nephropathy (DN) but the underlying mechanism remains unclear. This study was conducted to investigate whether human umbilical cord-MSCs (hUCMSCs) can induce oxidative damage ...
Ping Nie +8 more
doaj +1 more source
Frontiers in Immunology, 2021 Sepsis is a heterogeneous syndrome induced by infection and results in high mortality. Even though more than 100 biomarkers for sepsis prognosis were evaluated, prediction of patient outcomes in sepsis continues to be driven by clinical signs because of ...
Tingting Zhu +30 more
doaj +1 more source
Renal AA-amyloidosis in intravenous drug users - a role for HIV-infection? [PDF]
, 2012 Background: Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.
Amann, Kerstin Ute +7 more
core +2 more sources
Cleveland Clinic Journal of Medicine, 2023 Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis in the world. The etiology is unknown but a dysregulated T-cell immune response to viral, bacterial, and food antigens activating mucosal plasma cells to produce polymeric IgA has been proposed. No serological test exists to diagnosis IgAN.
Jonathan J, Taliercio, Ali, Mehdi
openaire +2 more sources
Climate change and the kidney [PDF]
, 2019 The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality.
Butler-Dawson, Jaime +12 more
core +1 more source
Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy [PDF]
, 2017 Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully elucidated. Deregulation of proteolytic systems is a known path leading to disease manifestation, therefore we hypothesized that proteases aberrantly ...
Bascands, Jean-Loup +15 more
core +2 more sources
The critical role of methylglyoxal and glyoxalase 1 in diabetic nephropathy [PDF]
, 2013 The discovery of increased formation of methylglyoxal (MG) by cell metabolism in high glucose concentration in vitro suggested possible relevance to diabetes and diabetes complications (1,2).
Rabbani, Naila, Thornalley, Paul J.
core +1 more source
Journal of the American Society of Nephrology, 2008 Pathogenic rodent-borne hantaviruses cause in humans generalized infections that involve the peripheral vascular bed and severely affect their permeability. We describe a 30-yr-old male patient with clinical symptoms characterizing five conventional phases of hemorrhagic fever with renal syndrome after an uncommonly severe hantavirus infection with the
Dusan, Ferluga, Alenka, Vizjak
openaire +2 more sources
Rituximab in patients with membranous nephropathy and kidney insufficiency
Frontiers in Pharmacology, 2022 Introduction: Patients with membranous nephropathy and kidney insufficiency have an extremely high risk of progression to end-stage renal disease. Whether rituximab can effectively treat membranous nephropathy patients with renal dysfunction remains ...
Yanhong Guo +8 more
doaj +1 more source
Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]
, 2015 Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E +14 more
core +1 more source