Results 31 to 40 of about 452,381 (401)
New England Journal of Medicine, 2001 BACKGROUND Diabetic nephropathy is the leading cause of end-stage renal disease. Interruption of the renin-angiotensin system slows the progression of renal disease in patients with type 1 diabetes, but similar data are not available for patients with ...
B. Brenner +9 more
semanticscholar +1 more source
Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice [PDF]
, 2016 Nephropathy is among the most frequent complications of diabetes and the leading cause of end-stage renal disease. Despite the success of novel drugs in animal models, the majority of the subsequent clinical trials employing those drugs targeting ...
Bascands, Jean-Loup +9 more
core +1 more source
New England Journal of Medicine, 1993 BACKGROUND Renal function declines progressively in patients who have diabetic nephropathy, and the decline may be slowed by antihypertensive drugs. The purpose of this study was to determine whether captopril has kidney-protecting properties independent
E. Lewis +3 more
semanticscholar +1 more source
Hyperglycemia and Hyperlipidemia Act Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB Mice [PDF]
, 2004 Diabetic nephropathy is the leading cause of end-stage renal disease in Western countries, but only a portion of diabetic patients develop diabetic nephropathy.
Alpers, Charles E. +6 more
core +1 more source
Association between thyroid hormones and diabetic kidney disease in Chinese adults
BMC Endocrine Disorders, 2023 Objective We aimed to explore the association between thyroid hormones and different stages of diabetic kidney disease (DKD) in Chinese adults. Methods This is a retrospective study involving 2,832 participants. DKD was diagnosed and classified according
Meng-chao Liu +8 more
doaj +1 more source
Identification of Genes Reveals the Mechanism of Cell Ferroptosis in Diabetic Nephropathy
Frontiers in Physiology, 2022 Aims/Introduction: Diabetic nephropathy (DN) is one of the main complications of diabetes. Genomics may reveal the essential pathogenesis of DN. We analyzed datasets to search for key genes to explore pathological mechanisms of DN.Materials and Methods ...
Xian Wang +11 more
doaj +1 more source
New England Journal of Medicine, 2001 BACKGROUND Microalbuminuria and hypertension are risk factors for diabetic nephropathy. Blockade of the renin-angiotensin system slows the progression to diabetic nephropathy in patients with type 1 diabetes, but similar data are lacking for hypertensive
H. Parving +5 more
semanticscholar +1 more source
Complement activation in IgA nephropathy
Seminars in Immunopathology, 2021 IgA nephropathy pathogenesis is incompletely understood, and this limits the development of disease-specific biomarkers and effective therapies. Evidence of complement activity in IgA nephropathy is well established.
N. Medjeral-Thomas +2 more
semanticscholar +1 more source
Journal of the American Society of Nephrology, 2020 BACKGROUND Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that produce short-chain fatty acids (SCFAs) through gut fermentation of fiber, in CKD and diabetes.
Y. Li +11 more
semanticscholar +1 more source