Results 31 to 40 of about 481,070 (386)

Identification of Genes Reveals the Mechanism of Cell Ferroptosis in Diabetic Nephropathy

Frontiers in Physiology, 2022
Aims/Introduction: Diabetic nephropathy (DN) is one of the main complications of diabetes. Genomics may reveal the essential pathogenesis of DN. We analyzed datasets to search for key genes to explore pathological mechanisms of DN.Materials and Methods ...
Xian Wang, Ling Jiang, Xue-Qi Liu, Yue-Bo Huang, Wei Zhu, Han-Xu Zeng, Li Gao, Li-Juan Ma, Meng-Ya Zhang, Qi-Jin Zhu, Yong-Gui Wu, Yong-Gui Wu   +11 more
doaj   +1 more source

Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]

, 2015
OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst, Cavalot, Chun Shing Kwok, Evangelos Kontopantelis, Foo, Grant Heatlie, Hermann, Iain Buchan, Kontopantelis, Lin, Maciejewski, Mamas A. Mamas, Martin K. Rutter, Phyo K. Myint, Raman, Saadia Aslam, Skriver, Sperrin, Yoon Loke   +18 more
core   +1 more source

Dietary interventions to contrast the onset and progression of diabetic nephropathy. a critical survey of new data [PDF]

, 2017
This article is a critical overview of recent contributions on the dietary corrections and the foods that have been claimed to delay or hinder the onset of diabetic nephropathy (DN) and its progression to end-stage renal disease.
Iacobini, Carla, Menini, Stefano, Pesce, Carlo, Pugliese, Giuseppe   +3 more
core   +1 more source

SDF4 Is a Prognostic Factor for 28-Days Mortality in Patients With Sepsis via Negatively Regulating ER Stress

Frontiers in Immunology, 2021
Sepsis is a heterogeneous syndrome induced by infection and results in high mortality. Even though more than 100 biomarkers for sepsis prognosis were evaluated, prediction of patient outcomes in sepsis continues to be driven by clinical signs because of ...
Tingting Zhu, Tingting Zhu, Tingting Zhu, Qun Su, Cuili Wang, Cuili Wang, Cuili Wang, Lingling Shen, Lingling Shen, Lingling Shen, Hongjun Chen, Hongjun Chen, Hongjun Chen, Shi Feng, Shi Feng, Shi Feng, Xiaofeng Peng, Xiaofeng Peng, Xiaofeng Peng, Siyu Chen, Siyu Chen, Siyu Chen, Yucheng Wang, Yucheng Wang, Yucheng Wang, Hong Jiang, Hong Jiang, Hong Jiang, Jianghua Chen, Jianghua Chen, Jianghua Chen   +30 more
doaj   +1 more source

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A.

Journal of the American Society of Nephrology, 2020
BACKGROUND Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that produce short-chain fatty acids (SCFAs) through gut fermentation of fiber, in CKD and diabetes.
Y. Li, Xiaochen Chen, Tony K Kwan, Y. Loh, J. Singer, Yunzi Liu, Jin Ma, Jian Tan, L. Macia, C. Mackay, S. Chadban, Hui-ling Wu   +11 more
semanticscholar   +1 more source

Membranous nephropathy

Brazilian Journal of Nephrology, 2023
ABSTRACT Membranous nephropathy is a glomerulopathy, which main affected target is the podocyte, and has consequences on the glomerular basement membrane. It is more common in adults, especially over 50 years of age. The clinical presentation is nephrotic syndrome, but many cases can evolve with asymptomatic non-nephrotic proteinuria.
Márcio Dantas, Lázaro Bruno Borges Silva, Barbhara Thaís Maciel Pontes, Marlene Antônia dos Reis, Patrícia Soares Nunes de Lima, Miguel Moysés Neto   +5 more
openaire   +5 more sources

Ameliorative role of SIRT1 in peritoneal fibrosis: an in vivo and in vitro study

Cell & Bioscience, 2021
Background Peritoneal fibrosis is one of the major complications induced by peritoneal dialysis (PD). Damaged integrity and function of peritoneum caused by peritoneal fibrosis not only limits the curative efficacy of PD and but affects the prognosis of ...
Yanhong Guo, Liuwei Wang, Rong Gou, Yulin Wang, Xiujie Shi, Yage Zhang, Xinxin Pang, Lin Tang   +7 more
doaj   +1 more source

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus [PDF]

, 2010
BACKGROUND: Diabetic nephropathy is a serious complication of diabetes mellitus and is associated with considerable morbidity and high mortality.
A Buja, A Helgadottir, A Subramanian, AE Teschendorff, Alexander P Maxwell, Andrew E Teschendorff, AS O'Connor, B He, B Krause, BH Ramsahoye, C Weigert, Christopher G Bell, D Ansell, D Ingrosso, DA Tregouet, David A Savage, EJ Richards, ER Seaquist, F Eckhardt, G Lund, H Al-Kateb, H Makino, HN Ibrahim, JD Storey, JF Navarro-Gonzalez, JJ Rogus, JT Leek, K Ichinose, M Bibikova, M Bibikova, M Quinn, MG Pezzolesi, MG Pezzolesi, MM Suzuki, MP Turunen, NM Goldenberg, P Katavetin, R Ihaka, R Lister, R Sladek, RA Irizarry, RC Gentleman, S Beck, S Saxonov, Stephan Beck, T Hastie, TA Down, TJ Ekstrom, TS Leak, U.S Renal Data System, Vardhman K Rakyan   +50 more
core   +4 more sources

Rituximab in patients with membranous nephropathy and kidney insufficiency

Frontiers in Pharmacology, 2022
Introduction: Patients with membranous nephropathy and kidney insufficiency have an extremely high risk of progression to end-stage renal disease. Whether rituximab can effectively treat membranous nephropathy patients with renal dysfunction remains ...
Yanhong Guo, Liuwei Wang, Yulin Wang, Xiaodan Li, Zihan Zhai, Lu Yu, Yan Liang, Peipei Liu, Lin Tang   +8 more
doaj   +1 more source

Differential renal effects of candesartan at high-and ultra-high doses in diabetic mice: potential role of  ACE2/AT2R/Mas [PDF]

, 2016
High doses of Ang II receptor (AT1R) blockers (ARBs) are renoprotective in diabetes. Underlying mechanisms remain unclear. We evaluated whether high/ultra-high doses of candesartan (ARB) up-regulate angiotensin-converting enzyme 2 (ACE2)/Ang II type 2 ...
Antunes, Tayze, Briones, Ana M., Burns, Kevin, Callera, Glaucia, Correa, Jose, Gutsol, Alexey, He, Ying, Montezano, Augusto C., Moorman, Danielle, Nguyen Dinh Cat, Aurelie, Touyz, Rhian M.   +10 more
core   +1 more source