Ameliorative role of SIRT1 in peritoneal fibrosis: an in vivo and in vitro study
Cell & Bioscience, 2021 Background Peritoneal fibrosis is one of the major complications induced by peritoneal dialysis (PD). Damaged integrity and function of peritoneum caused by peritoneal fibrosis not only limits the curative efficacy of PD and but affects the prognosis of ...
Yanhong Guo +7 more
doaj +1 more source
Rituximab in patients with membranous nephropathy and kidney insufficiency
Frontiers in Pharmacology, 2022 Introduction: Patients with membranous nephropathy and kidney insufficiency have an extremely high risk of progression to end-stage renal disease. Whether rituximab can effectively treat membranous nephropathy patients with renal dysfunction remains ...
Yanhong Guo +8 more
doaj +1 more source
Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy [PDF]
, 2017 Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully elucidated. Deregulation of proteolytic systems is a known path leading to disease manifestation, therefore we hypothesized that proteases aberrantly ...
Bascands, Jean-Loup +15 more
core +2 more sources
Renal AA-amyloidosis in intravenous drug users - a role for HIV-infection? [PDF]
, 2012 Background: Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.
Amann, Kerstin Ute +7 more
core +2 more sources
Climate change and the kidney [PDF]
, 2019 The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality.
Butler-Dawson, Jaime +12 more
core +1 more source
Environmental Health Perspectives, 1976 The purpose of this paper is to review the development of the mammalian kidney and to assess the influence that various perinatal manipulations may have on the developmental process either morphologically or functionally. Immature kidneys in general have less functional capacity than adult kidneys and a low rate of glomerular filtration, perhaps ...
openaire +2 more sources
Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]
, 2018 Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J. +2 more
core +1 more source
Critical Role of Cysteine-Rich Protein 61 in Mediating the Activation of Renal Fibroblasts
Frontiers in Physiology, 2019 ObjectiveTo explore the expression of cysteine-rich protein 61 (Cyr61) in ischemic renal fibrosis and the role of Cyr61 in mediating the activation of renal fibroblasts.Methods(1) The rat model of renal fibrosis was established after ischemia-reperfusion
Hang Liu +10 more
doaj +1 more source
Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]
, 2015 Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E +14 more
core +1 more source
Preoperative proteinuria may be a risk factor for postoperative acute kidney injury：a meta-analysis
Renal Failure, 2021 Objective To investigate the relationship between preoperative proteinuria and postoperative acute kidney injury (AKI). Methods We performed a search on databases included PubMed, Embase, the Cochrane Library, and Web of Science, from December 2009 to ...
Dan-Dan Huang +3 more
doaj +1 more source